8 research outputs found
Evolució i tendències en el disseny urbanÃstic dels parcs cientÃfics i tecnològics espanyols
L'objecte d'aquest article és presentar els resultats d'un estudi sobre l'evolució i les tendències en el disseny urbanÃstic dels parcs cientÃfics i tecnològics espanyols. Aquest estudi s'ha fet com a part dels treballs previs per a la redacció del Pla especial urbanÃstic del turó de Gardeny, un document encarregat per l'Ajuntament de Lleida, l'any 2009, per repensar i actualitzar l'ordenació ur- banÃstica del Parc CientÃfic i Tecnològic Agroalimentari (PCITAL) d'aquesta ciutat. [...
Oxidative Stress in Structural Valve Deterioration : A Longitudinal Clinical Study
The cause of structural valve deterioration (SVD) is unclear. Therefore, we investigated oxidative stress markers in sera from patients with bioprosthetic heart valves (BHVs) and their association with SVD. Blood samples were taken from SVD (Phase A) and BHV patients during the first 24 (Phase B1) and >48 months (Phase B2) after BHV implantation to assess total antioxidant capacity (TAC), malondialdehyde (MDA), and nitrotyrosine (NT). The results show that MDA levels increased significantly 1 month after surgery in all groups but were higher at 6 months only in incipient SVD patients. NT levels increased gradually for the first 24 months after implantation in the BHV group. Patients with transcatheter aortic valve implantation (TAVI) showed even higher levels of stress markers. After >48 months, MDA and NT continued to increase in BHV patients with a further elevation after 60-72 months; however, these levels were significantly lower in the incipient and established SVD groups. In conclusion, oxidative stress may play a significant role in SVD, increasing early after BHV implantation, especially in TAVI cases, and also after 48 months' follow-up, but decreasing when SVD develops. Oxidative stress potentially represents a target of therapeutic intervention and a biomarker of BHV dysfunctio
De Barcelona a Guangzhou
Xavier Majoral, de l'empresa Stimulo, parla de la seva experiència, coneixements, manera de fer i entendre una agència de disseny industrial del segle XXI.Xavier Majoral, de l'empresa Stimulo, parla de la seva experiència, coneixements, manera de fer i entendre una agència de disseny industrial del segle XXI
Funcionament de l'aula docent a l'ESEIAAT 4
Funcionament de l'aula docent a l'ESEIAATAula docent virtual, aplicacions (accés a les dades des de Radi unitat H:\ USB, pendrive i CD / DVD) Funcionament de l'aula docent a l'ETSEIATT 1Aula docent virtual, què ens aporta?Funcionament de l'aula docent a l'ESEIAAT 2Aula docent virtual, com accedir-hi?(Usuari i contransenya)Funcionament de l'aula docent a l'ESEIAAT 3Aula docent virtual, aplicacions o escrip...
D1.1 Case studies and evaluation criteria
This report presents the activities and results of Tasks 1.1 and 1.2 of the SPARK project. The objectives of these activities were: To define an initial set of case studies whose characteristics are relevant to study and analyse the dynamics of the co-creative design process. To define tailored metrics to evaluate the relevant aspects of the co-creative design process.For Task 1.1 the following case study selection criteria were defined: Be representative of the range of projects typically completed by agencies in the ‘creative industries’; Provide a range of products that will be technically challenging for the SPARK platform; Test the ability of the SPARK platform for user interaction and user interface design; Availability of client and stage of project
Oxidative Stress in Structural Valve Deterioration: A Longitudinal Clinical Study
International audienceThe cause of structural valve deterioration (SVD) is unclear. Therefore, we investigated oxidative stress markers in sera from patients with bioprosthetic heart valves (BHVs) and their association with SVD. Blood samples were taken from SVD (Phase A) and BHV patients during the first 24 (Phase B1) and >48 months (Phase B2) after BHV implantation to assess total antioxidant capacity (TAC), malondialdehyde (MDA), and nitrotyrosine (NT). The results show that MDA levels increased significantly 1 month after surgery in all groups but were higher at 6 months only in incipient SVD patients. NT levels increased gradually for the first 24 months after implantation in the BHV group. Patients with transcatheter aortic valve implantation (TAVI) showed even higher levels of stress markers. After >48 months, MDA and NT continued to increase in BHV patients with a further elevation after 60–72 months; however, these levels were significantly lower in the incipient and established SVD groups. In conclusion, oxidative stress may play a significant role in SVD, increasing early after BHV implantation, especially in TAVI cases, and also after 48 months’ follow-up, but decreasing when SVD develops. Oxidative stress potentially represents a target of therapeutic intervention and a biomarker of BHV dysfunction