Involvement of Oxidative Stress in Cardiovascular Diseases

Many research studies support the evidence that free radicals stress is involved in the pathogenesis of many diseases in human and animals. The current review aimed to throw the light on sources of free radicals in the cardiovascular system, involvement of oxidative stress in cardiovascular diseases and the role of the antioxidants in alleviating the damage produced by oxidative stress

The Role of Liver Biopsy in Detection of Hepatic Oxidative Stress

The goal of the current paper is to explore the role of liver biopsy as a tool in detection of hepatic oxidative stress, with brief notes on different types of free radicals, antioxidants, hepatic and blood oxidative stress, and lipid peroxidation. Hepatic oxidative stress was investigated for many years in human and animals, but most of the studies performed in animals were concerned with studying oxidative status in the liver tissues after slaughtering or euthanasia. However, in human medicine, a large number of studies were implemented to investigate the status of antioxidants in liver biopsy specimens. Similar studies are required in animals, as the changes in hepatic antioxidants and formation of lipid peroxide give a good idea about the condition of the liver. On the other hand, hepatic disease may present without significant effect on blood oxidative status, and, consequently, the best way to detect the status of hepatic oxidants and antioxidants is through measuring in liver biopsy. Measuring antioxidants status directly in the liver tissues gives an accurate estimation about the condition of the liver, permits the diagnosis of hepatic dysfunction, and helps to determine the degree of deterioration in the hepatic cells

Oxidant and Antioxidants During the Transition Period in Dairy Cows: https://doi.org/10.5281/zenodo.8224852

The transition from pregnancy to parturition is associated with metabolic and physiological changes. Oxidative stress is increased in late pregnancy and continue to be higher after parturition, which represent a challenge for the dairy cows to defend the increased free radicals by using the available antioxidants. This review discussed the process of free radical release, the development of oxidative stress and evaluation of the animal health during the transition period and threw the light on different methods used to assess oxidative stress and antioxidants therapy

Comparison of Normal Hematological and Biochemical values in Male and Female buffaloes

The present study was undertaken to evaluate the effect of difference in gender on some hematological and serum biochemical constituents in buffaloes. In total, 30 healthy buffaloes (1–2 years old) of both sexes were examined at various buffalo farms in Assiut, Egypt. Two blood samples were collected from the jugular vein. The first blood sample was used for biochemical analysis. The second blood sample was used for hematological analysis. The results revealed significant increases in serum levels of most of the measured biochemical parameters in male than in female buffaloes, except serum albumen and blood urea nitrogen levels, which were significantly higher (P<0.01) in female buffaloes. In addition, no significant changes were observed in serum total proteins and globulins levels, and in serum gamma glutamyl transferase and alkaline phosphatase activities. There were significant increases in hematocrit % (P<0.01) and mean corpuscular volume (P<0.05) in female than in male buffaloes. Mean corpuscular hemoglobin concentration was significantly lower (P<0.01) in female than in male buffaloes. No significant changes were reported in leucocytes and platelets. It could be concluded that hematological and serum biochemical constituents are varied between male and female buffaloes, which necessities the importance of using separate groups from male and female buffaloes in research studies

Oxidative stress and bovine liver diseases: Role of glutathione peroxidase and glucose６‐phosphate dehydrogenase

This article summarizes the different types of free radicals, antioxidants and the effect of oxidative stress on the activities of glutathione peroxidase and glucose6-phosphate dehydrogenase in bovine liver diseases. A growing body of evidence suggests that the formation of reactive oxygen species is a common occurrence associated with most if not all disease processes. The overall importance of reactive oxygen species to the progression and severity of various disease states varies greatly depending on the conditions and whether the disease is acute or chronic. Free radical researches in animals are in progress and further investigations are needed to establish the involvement of reactive oxygen species in diseases affecting different animal species and the pathology they produce

Comparison of Normal Hematological and Biochemical values in Male and Female buffaloes

The present study was undertaken to evaluate the effect of difference in gender on some hematological and serum biochemical constituents in buffaloes. In total, 30 healthy buffaloes (1–2 years old) of both sexes were examined at various buffalo farms in Assiut, Egypt. Two blood samples were collected from the jugular vein. The first blood sample was used for biochemical analysis. The second blood sample was used for hematological analysis. The results revealed significant increases in serum levels of most of the measured biochemical parameters in male than in female buffaloes, except serum albumen and blood urea nitrogen levels, which were significantly higher (P<0.01) in female buffaloes. In addition, no significant changes were observed in serum total proteins and globulins levels, and in serum gamma glutamyl transferase and alkaline phosphatase activities. There were significant increases in hematocrit % (P<0.01) and mean corpuscular volume (P<0.05) in female than in male buffaloes. Mean corpuscular hemoglobin concentration was significantly lower (P<0.01) in female than in male buffaloes. No significant changes were reported in leucocytes and platelets. It could be concluded that hematological and serum biochemical constituents are varied between male and female buffaloes, which necessities the importance of using separate groups from male and female buffaloes in research studies