More terminological clarity in the interprofessional field - a call for reflection on the use of terminologies, in both practice and research, on a national and international level

The terminology which has been used up until now within interprofessional healthcare has been characterised by a certain definitional weakness, which, among other factors, has been caused by an uncritical adoption of language conventions and a lack of theoretical reflection. However, as terminological clarity plays a significant role in the development and profiling of a discipline, the clarification and definition of commonly-used terminology has manifested itself as a considerable objective for the interprofessional research community. One of the most important journals for research in the area of interprofessional education and care, the Journal of Interprofessional Care, has expanded its author guidelines relating to terminology, modeled after the conceptual considerations of the research group around Barr et. al and Reeves et al. A German translation of the suggested terms therein has been presented in this contribution, and discussed in light of the challenges to a possible adaptation for the German-speaking world. The objective is to assist communication in practice and research in becoming clearer, while promoting an increasing awareness to and the transparency of determined definitions and terminologies

Flavor composition of transgenic raspberry bushy dwarf virus-resistant 'Meeker' raspberries

Raspberries have been popular since the time of the ancient Greeks. Red raspberries are cultivated throughout the world, particularly in the Pacific Northwest region of the United States and Canada. The raspberry bushy dwarf virus (RBDV) causes significant reduction in yield and crumbly fruit in raspberries, blackberries and raspberry-blackberry hybrids. There is no effective treatment once a plant is infected and the only effective prevention is using resistant varieties. Resistance is difficult to attain using traditional cultivation techniques. Through transgenic modification, five lines of resistant red raspberries have been developed from the 'Meeker' cultivar. To investigate trueness to type, flavor characteristics for raspberries grown in Oregon and Washington during 2004 and 2005 were compared. Aroma volatiles important to the raspberry aroma profile were quantified, as well as the sugar and organic acid profiles, to compare the five transgenic 'Meeker' lines with the wild type 'Meeker', 'Chilliwack', 'Tulameen', 'Willamette' and 'Yellow Meeker'. Thirty aroma compounds ((Z)-3-hexenol, 4-isopropylbenzyl alcohol, 6- methyl-5-hepten-2-ol, 2-nonanol, hexanal, (E)-2-hexenal, (Z)-3-hexenyl acetate, ethyl hexanoate, methyl nonanoate, 2-heptanone, 2-nonanone, raspberry ketone, zingerone, δ-octalactone, δ-decalactone, para-cymene, geraniol, α-ionone, β-ionone, limonene, linalool, myrcene, nerol, α-phellandrene, α-pinene, sabinene, α-terpinene, γ-terpinene, α-terpineol, terpinen-4-ol and terpinolene) were selected and quantified using stir bar sorptive extraction (SBSE) paired with gas chromatography-mass spectrometry (GC-MS) in all raspberry samples. The chiral stereoisomers of some volatile compounds in these raspberries were also studied using a cyclosilB GC column. Different raspberry cultivars varied widely in titratable acidity, sugar and acid concentration, and volatile composition, particularly α-ionone, linalool and (Z)-3-hexenol. Chiral compositions were also quite different among the cultivars studied. For the wild type 'Meeker' and RBDV-resistant varieties, flavor variations were observed from sites to sites and year to year. However, overall volatile profile had much less variations compared with sugar and organic acid profiles. None of the analyses separated the transgenic 'Meeker' raspberries from the wild type 'Meeker', and result was consistent for both of the locations and years studied. The results suggested that the transgenic RBDV-resistant 'Meeker' varieties were not different from the wild type 'Meeker' raspberry

Translation and psychometric properties of the German version of the University of the West of England Interprofessional Questionnaire (UWE-IP)

© 2017 Taylor & Francis. The implementation of a bachelor degree in Interprofessional Health Care at the University of Heidelberg, Germany, has fostered the need to evaluate the impact of this innovative programme. The University of the West of England Interprofessional Questionnaire (UWE-IP) was developed for longitudinal evaluation of an interprofessional curriculum. The UWE-IP consists of 35 items in four scales: “Communication and Teamwork Scale,” “Interprofessional Learning Scale,” “Interprofessional Interaction Scale,” and “Interprofessional Relationships Scale.” The UWE-IP was translated to German according to international guidelines. Psychometrics were assessed: reliability of the four scales was tested with Cronbach‘s alpha and confirmatory factor analysis was performed to examine the underlying factor structure. The sample consisted of 326 datasets. Reliability for the scales was between 0.75 and 0.90. The underlying factor structure showed a good fit. We conclude that the German UWE-IP shows good psychometrics and recommend its use for evaluation of interprofessional learning activities. These results add to the body of knowledge on evaluation instruments in interprofessional education

Voluntary Medical Male Circumcision: A Qualitative Study Exploring the Challenges of Costing Demand Creation in Eastern and Southern Africa

BACKGROUND: This paper proposes an approach to estimating the costs of demand creation for voluntary medical male circumcision (VMMC) scale-up in 13 countries of eastern and southern Africa. It addresses two key questions: (1) what are the elements of a standardized package for demand creation? And (2) what challenges exist and must be taken into account in estimating the costs of demand creation? METHODS AND FINDINGS: We conducted a key informant study on VMMC demand creation using purposive sampling to recruit seven people who provide technical assistance to government programs and manage budgets for VMMC demand creation. Key informants provided their views on the important elements of VMMC demand creation and the most effective funding allocations across different types of communication approaches (e.g., mass media, small media, outreach/mobilization). The key finding was the wide range of views, suggesting that a standard package of core demand creation elements would not be universally applicable. This underscored the importance of tailoring demand creation strategies and estimates to specific country contexts before estimating costs. The key informant interviews, supplemented by the researchers' field experience, identified these issues to be addressed in future costing exercises: variations in the cost of VMMC demand creation activities by country and program, decisions about the quality and comprehensiveness of programming, and lack of data on critical elements needed to "trigger the decision" among eligible men. CONCLUSIONS: Based on this study's findings, we propose a seven-step methodological approach to estimate the cost of VMMC scale-up in a priority country, based on our key assumptions. However, further work is needed to better understand core components of a demand creation package and how to cost them. Notwithstanding the methodological challenges, estimating the cost of demand creation remains an essential element in deriving estimates of the total costs for VMMC scale-up in eastern and southern Africa

German translation of the Alberta context tool and two measures of research use: methods, challenges and lessons learned

Background: Understanding the relationship between organizational context and research utilization is key to reducing the research-practice gap in health care. This is particularly true in the residential long term care (LTC) setting where relatively little work has examined the influence of context on research implementation. Reliable, valid measures and tools are a prerequisite for studying organizational context and research utilization. Few such tools exist in German. We thus translated three such tools (the Alberta Context Tool and two measures of research use) into German for use in German residential LTC. We point out challenges and strategies for their solution unique to German residential LTC, and demonstrate how resolving specific challenges in the translation of the health care aide instrument version streamlined the translation process of versions for registered nurses, allied health providers, practice specialists, and managers. Methods: Our translation methods were based on best practices and included two independent forward translations, reconciliation of the forward translations, expert panel discussions, two independent back translations, reconciliation of the back translations, back translation review, and cognitive debriefing. Results: We categorized the challenges in this translation process into seven categories: (1) differing professional education of Canadian and German care providers, (2) risk that German translations would become grammatically complex, (3) wordings at risk of being misunderstood, (4) phrases/idioms non-existent in German, (5) lack of corresponding German words, (6) limited comprehensibility of corresponding German words, and (7) target persons’ unfamiliarity with activities detailed in survey items. Examples of each challenge are described with strategies that we used to manage the challenge. Conclusion: Translating an existing instrument is complex and time-consuming, but a rigorous approach is necessary to obtain instrument equivalence. Essential components were (1) involvement of and co-operation with the instrument developers and (2) expert panel discussions, including both target group and content experts. Equivalent translated instruments help researchers from different cultures to find a common language and undertake comparative research. As acceptable psychometric properties are a prerequisite for that, we are currently carrying out a study with that focus

Iwasawa theory and p-adic L-functions over Zp2-extensions

We construct a two-variable analogue of Perrin-Riou’s p-adic regulator map for the Iwasawa cohomology of a crystalline representation of the absolute Galois group of Q p , over a Galois extension whose Galois group is an abelian p-adic Lie group of dimension 2. We use this regulator map to study p-adic representations of global Galois groups over certain abelian extensions of number fields whose localisation at the primes above p is an extension of the above type. In the example of the restriction to an imaginary quadratic field of the representation attached to a modular form, we formulate a conjecture on the existence of a “zeta element”, whose image under the regulator map is a p-adic L-function. We show that this conjecture implies the known properties of the 2-variable p-adic L-functions constructed by Perrin-Riou and Kim

"After my husband's circumcision, I know that I am safe from diseases": Women's Attitudes and Risk Perceptions Towards Male Circumcision in Iringa, Tanzania.

While male circumcision reduces the risk of female-to-male HIV transmission and certain sexually transmitted infections (STIs), there is little evidence that circumcision provides women with direct protection against HIV. This study used qualitative methods to assess women's perceptions of male circumcision in Iringa, Tanzania. Women in this study had strong preferences for circumcised men because of the low risk perception of HIV with circumcised men, social norms favoring circumcised men, and perceived increased sexual desirability of circumcised men. The health benefits of male circumcision were generally overstated; many respondents falsely believed that women are also directly protected against HIV and that the risk of all STIs is greatly reduced or eliminated in circumcised men. Efforts to engage women about the risks and limitations of male circumcision, in addition to the benefits, should be expanded so that women can accurately assess their risk of HIV or STIs during sexual intercourse with circumcised men

REQUIEM-2D: Spatially Resolved Stellar Populations from HST 2D Grism Spectroscopy

We present a novel Bayesian methodology to jointly model photometry and deep Hubble Space Telescope (HST) 2d grism spectroscopy of high-redshift galaxies. Our requiem2d code measures both unresolved and resolved stellar populations, ages, and star-formation histories (SFHs) for the ongoing REQIUEM (REsolving QUIEscent Magnified) Galaxies Survey, which targets strong gravitationally lensed quiescent galaxies at z~2. We test the accuracy of \texttt{requiem2d} using a simulated sample of massive galaxies at z~2 from the Illustris cosmological simulation and find we recover the general trends in SFH and median stellar ages. We further present a pilot study for the REQUIEM Galaxies Survey: MRG-S0851, a quintuply-imaged, massive ($\log M_* / M_\odot = 11.02 \pm 0.04$) red galaxy at $z=1.883\pm 0.001$. With an estimated gravitational magnification of $\mu = 5.7^{+0.4}_{-0.2}$, we sample the stellar populations on 0.6 kpc physical size bins. The global mass-weighted median age is constrained to be $1.8_{-0.2}^{+0.3}$ Gyr, and our spatially resolved analysis reveals that MRG-S0851 has a flat age gradient in the inner 3 kpc core after taking into account the subtle effects of dust and metallicity on age measurements, favoring an early formation scenario. The analysis for the full REQUIEM-2D sample will be presented in a forthcoming paper with a beta-release of the requiem2d code.Comment: 29 pages, 19 figures, accepted for publication in Ap