Partitionning medical image databases for content-based queries on a grid

articleInternational audienceIn this article we study the impact of executing a medical image database query application on the grid. For lowering the total computation time, the image database is partitioned in subsets to be processed on different grid nodes. A theoretical model of the application computation cost and estimates of the grid execution overhead are used to efficiently partition the database. We show results demonstrating that smart partitioning of the database can lead to significant improvements in terms of total computation time

gtk-fortran: a GTK+ binding to build Graphical User Interfaces in Fortran

International audienc

Examining readmission factors in psychiatric emergency care for individuals with personality disorders: A 6-year retrospective study

People with personality disorders (PDs) are often admitted to psychiatric emergency services due to the frequent repetition of acute crises. This study drew on the ICD diagnostic records of 2,634 individuals with PDs who were admitted to a specialized inpatient psychiatric crisis unit over a 6-year period.Multiple logistic regressions and survival regressionswere performed to examinewhether PD categories, gender, and other individual, interpersonal, and precipitating factors were associated with readmission and time-to-readmission. The results showed a 16.1% readmission rate. Of these, 99.5% of readmissions occurred within 4 years following the first admission. Gender was the main factor associated with both readmission and time-to-readmission: while men were readmitted faster, more women in total were readmitted for a second psychiatric emergency hospitalization. Findings also indicated that readmission rate and time-to-readmission differed following the category of PD: readmission rate in a ratio of 1–2 (from 8% to 10% for dissocial and paranoid PD up to 19%–21%for impulsive and borderline PD), and time-to-readmission in a ratio of 1–5 (from 1month for anankastic and dependent, to 5 months for impulsive, histrionic and anxious-avoidant PD). Limitations of this naturalistic study include a lack of self-reported measures and generalizability to less specialized emergency settings. Future research should include a prospective longitudinal design using standardized scalablemeasurement tools to improve the completeness and accuracy of the data concerning the psychological processes involved in risk and time-to-readmission after brief hospitalizations in emergency psychiatry

Medical Image Content-Based Queries using the Grid

International audienceComputation and data grids have encountered a large success among the scientific computing community in the past few years. The medical imaging community is increasingly aware of the potential benefit of these technologies in facing today medical image analysis challenges. In this paper, we report on a first experiment in deploying a medical application on a large scale grid testbed. Our pilot application is a hybrid metadata and image content-based query system that manipulates a large data set and for which image analysis computation can be easily parallelized on several grid nodes. We analyze the performances of this algorithm and the benefit brought by the grid. We further discuss possible improvements and future trends in porting medical applications to grid infrastructures

Segmentation et suivi de mouvement d'objets déformables par région active

Nous proposons un nouveau type de modèle déformable appelé région active pour la segmentation avec connaissance d'un modèle géométrique. Le modèle consiste en une région dotée de propriétés d'élasticité qui garantissent des déformations cohérentes, en particulier dans le cas d'un objet aux interfaces multiples. Pour conserver cependant un contrôle précis de la régularité des interfaces, chacune d'entre elles possède une flexibilité propre, analogue à celle d'un contour actif. Le modèle de région active est mis en oeuvre pour la segmentation conjointe des interfaces du ventricule gauche du coeur en IRM

The calcareous tufa of La Thomassine: Early Neolithic landscapes and climates in the Manosque countryside

Le tuf calcaire de la Thomassine, localise sur le site même de la Maison de la Biodiversité à Manosque (Alpes-de- Haute-Provence), fait actuellement l’objet d’une étude pluridisciplinaire afin de reconstituer les rythmes de l’évolution du paysage dans le secteur de Manosque. Les analyses géomorphologiques, les datations radiocarbone et l’étude des assemblages de gastéropodes contenus dans les sédiments, permettent de caractériser différentes composantes de l’environnement du Luberon au début du Néolithique, il y a plus de 6500 ans.The Thomassine calcareous tufa, located near the “Biodiversity House” (Manosque, Alpes-de-Haute-Provence), is currently the subject of a multidisciplinary study to reconstruct the rhythms of the landscape changes in the Manosque area. Geomorphological analysis, radiocarbon dating and land snail assemblage studies are used to characterize the various components of the Luberon environment in the Early Neolithic, more than 6,500 years ago

The state of Fortran

A community of developers has formed to modernize the Fortran ecosystem. In this article, we describe the high-level features of Fortran that continue to make it a good choice for scientists and engineers in the 21st century. Ongoing efforts include the development of a Fortran standard library and package manager, the fostering of a friendly and welcoming online community, improved compiler support, and language feature development. The lessons learned are common across contemporary programming languages and help reduce the learning curve and increase adoption of Fortran

Professional Exposure to Goats Increases the Risk of Pneumonic-Type Lung Adenocarcinoma: Results of the IFCT-0504-Epidemio Study

Pneumonic-type lung adenocarcinoma (P-ADC) represents a distinct subset of lung cancer with specific clinical, radiological, and pathological features. Given the weak association with tobacco-smoking and the striking similarities with jaagsiekte sheep retrovirus (JSRV)-induced ovine pulmonary adenocarcinoma, it has been suggested that a zoonotic viral agent infecting pulmonary cells may predispose to P-ADC in humans. Our objective was to explore whether exposure to domestic small ruminants may represent a risk factor for P-ADC. We performed a multicenter case-control study recruiting patients with P-ADC as cases and patients with non-P-ADC non-small cell lung cancer as controls. A dedicated 356-item questionnaire was built to evaluate exposure to livestock. A total of 44 cases and 132 controls were included. At multivariate analysis, P-ADC was significantly more associated with female gender (Odds-ratio (OR) = 3.23, 95% confidence interval (CI): 1.32–7.87, p = 0.010), never- smoker status (OR = 3.57, 95% CI: 1.27–10.00, p = 0.015), personal history of extra-thoracic cancer before P-ADC diagnosis (OR = 3.43, 95% CI: 1.10–10.72, p = 0.034), and professional exposure to goats (OR = 5.09, 95% CI: 1.05–24.69, p = 0.043), as compared to other subtypes of lung cancer. This case-control suggests a link between professional exposure to goats and P-ADC, and prompts for further epidemiological evaluation of potential environmental risk factors for P-ADC