Factors related to the fatigue of relief workers in areas affected by the Great East Japan Earthquake : survey results 2.5 years after the disaster

Background: After the Great East Japan Earthquake (March 11, 2011), the fatigue of relief workers became a major problem in affected areas. In the present study, we conducted a questionnaire survey 2.5 years post-disaster identifying factors related to the fatigue of relief workers. Methods: This survey was cross-sectional and participants (N = 119) were relief workers living in affected areas. We used a self-administered questionnaire which included participants’ current problems, sources of strong feeling of loss, psychological distress and compassion fatigue. Based on answers (Yes/No) to the fatigue item, we created 2 groups; a Fatigue-group and a Non-fatigue group. We employed bivariate analysis on items with significant differences between the two groups and entered them into a multivariable logistic regression model. Results: Fifty-seven (48%) reported that they were “very tired” and were assigned to the Fatigue group. The total score of the 6-item Kessler Psychological Distress Scale (K6) and each subscale score (burnout, secondary trauma, and compassion satisfaction) of the Professional Quality of Life measure (Pro-QOL) in the Fatigue group were significantly higher than those in the Non-fatigue group. There were significant differences between the two groups for 11 items relating to current problems and sources of strong feelings of loss, and the following items were extracted as factors related to the fatigue of relief workers: loss of trust in others (adjusted OR, 10.03: 95%CI, 2.30–43.79), no confidence to continue work (adjusted OR, 6.27: 95%CI, 1.72–22.83), loss of important person(s) (adjusted OR, 5.58: 95%CI, 2.05–15.19), and sleep disturbance (adjusted OR, 5.14: 95%CI, 1.93–13.67). Conclusion: Many relief workers who reported fatigue had experienced various losses and current problems. Adequate consideration and care systems for local relief workers with fatigue should be given for a long-period after a disaster and it is important for the workers themselves to continue accepting support from others and maintaining self-care habits

Cloning of an isoform of mouse TGF-β type II receptor gene

AbstractA variant of transforming growth factor-β type II receptor (TGF-βRII) cDNA was isolated from a mouse brain cDNA library. The predicted receptor is identical to previously reported mouse TGF-βRII except that the isoform has an insertion sequence of 25 amino acids in the predicted ligand-binding domain. By the use of reverse transcription-polymerase chain reaction (RT-PCR), transcripts for both isoforms were detected in all tissues and developing embryos examined. The isoform transiently expressed in COS cells showed a similar ligand-binding specificity to authentic TGF-βRII. These results suggest that the mouse TGF-βRII gene generates multiple isoforms, possibly by alternative splicing, as reported for activin type IIB receptor; and an isoform which has the extra sequence in the ligand-binding domain is also involved in the TGF-β signal transduction

Children’s Perception of Cancer and Survivors After a Cancer Education Program Engaging with Survivors: A Qualitative Study

Background: In Japan, cancer education utilizing external lecturers are being promoted as part of cancer control measures. The objective of this study was to clarify children’s perceptions of cancer and survivors and their awareness of actions for early prevention and detection of cancer after participating in a cancer education program engaging with survivors.Methods: This study was conducted during January and March 2020, using the qualitative analysis method. Homeroom teachers gave a lesson on cancer to sixth-grade students (n=69) at an elementary school in Japan. Two weeks later, a cancer survivor gave a follow-up class. Then an inductive content analysis was conducted on the content of the post-class reflection worksheets written by students.Results: After analyzing the worksheets of 59 students, they learned that “to reduce the risk of developing cancer, one should lead a healthy lifestyle” and “strive for early detection through cancer screening” through the education program. As things they can do themselves in the future, they listed “encourage family members to get cancer screenings,” “quit smoking,” and “cut back on alcohol.” In addition, children have deepened their understanding of cancer survivors and learned the importance of their own and others’ lives.Conclusion: The results suggested that children gained practical knowledge about cancer through the program and deepened their understanding of cancer and survivors by directly interacting with and listening to survivors

Origin of Thermal and Non-Thermal Hard X-ray Emission from the Galactic Center

We analyse new results of Chandra and Suzaku which found a flux of hard X-ray emission from the compact region around Sgr A$^\ast$ (r ~ 100 pc). We suppose that this emission is generated by accretion processes onto the central supermassive blackhole when an unbounded part of captured stars obtains an additional momentum. As a result a flux of subrelativistic protons is generated near the Galactic center which heats the background plasma up to temperatures about 6-10 keV and produces by inverse bremsstrahlung a flux of non-thermal X-ray emission in the energy range above 10 keV.Comment: to be published in PASJ, v.61, No.5, 200