A coated-wire ion-selective electrode for ionic calcium measurements

A coated-wire ion-selective electrode for measuring ionic calcium was developed, in collaboration with Teknektron Sensor Development Corporation (TSDC). This coated wire electrode sensor makes use of advanced, ion-responsive polyvinyl chloride (PVC) membrane technology, whereby the electroactive agent is incorporated into a polymeric film. The technology greatly simplifies conventional ion-selective electrode measurement technology, and is envisioned to be used for real-time measurement of physiological and environment ionic constituents, initially calcium. A primary target biomedical application is the real-time measurement of urinary and blood calcium changes during extended exposure to microgravity, during prolonged hospital or fracture immobilization, and for osteoporosis research. Potential advanced life support applications include monitoring of calcium and other ions, heavy metals, and related parameters in closed-loop water processing and management systems. This technology provides a much simplified ionic calcium measurement capability, suitable for both automated in-vitro, in-vivo, and in-situ measurement applications, which should be of great interest to the medical, scientific, chemical, and space life sciences communities

Proposed magneto-electrostatic ring trap for neutral atoms

We propose a novel trap for confining cold neutral atoms in a microscopic ring using a magneto-electrostatic potential. The trapping potential is derived from a combination of a repulsive magnetic field from a hard drive atom mirror and the attractive potential produced by a charged disk patterned on the hard drive surface. We calculate a trap frequency of [29.7, 42.6, 62.8] kHz and a depth of [16.1, 21.8, 21.8] MHz for [133Cs, 87Rb, 40K], and discuss a simple loading scheme and a method for fabrication. This device provides a one-dimensional potential in a ring geometry that may be of interest to the study of trapped quantum degenerate one-dimensional gases.Comment: 4 pages, 2 figures; revised, including new calculations and further discussio

Strong solutions of SDEs with singular (form-bounded) drift via Roeckner-Zhao approach

We use the approach of Roeckner-Zhao to prove strong well-posedness for SDEs with singular drift satisfying some minimal assumptions

Dual Stage Microvalue and Method of Use

A micro-machined drug delivery device and method of use for the delivery of labile drugs is disclosed. A micro-machined sensing device and method of use is also disclosed. A micro-machined drug delivery and sensing device and method of use is additionally disclosed. All three devices are intended to be inserted into a patient\u27s body. The drug delivery devices allow for the mixing of drug components prior to the release of the mixture into the patient\u27s body where the mixture is labile. The micro-machined sensing device is suitable for monitoring the concentration of a specific chemical in a patient\u27s body fluids when the monitoring requires a labile reagent that must be mixed prior to introduction of the body fluid into the sensing device. The micro-machined drug delivery and sensing device is especially applicable in situations where the prompt delivery of labile drugs is necessary

Understanding obfuscated code

Code obfuscation makes it harder for a security analyst to understand the malicious payload of a program. In most cases an analyst needs to study the program at the machine code level, with little or no extra information available, apart from his experience. An unexperienced analyst is confronted with a steep learning curve, as understanding unobfuscated machine code already requires some skills. We have built LOCO, a graphical, interactive environment to help a security analyst improving his skills in understanding obfuscated code. 1

Production of carbonized micro-patterns by photolithography and pyrolysis

The preparation of carbon micro-patterns is reported in this paper. Different carbon micro-patterns were created using photolithography of the epoxy-based negative photoresist SU-8. Photoresist patterns were optimized in terms of resolution and aspect ratio and subsequently subjected to pyrolysis to obtain carbonized and conductive 3D structures. The latter step requires the optimization of the resist cross-linking time as well as the temperature and time of the resist post-bake. This step is crucial in order to avoid any severe modification of the geometry of the patterns produced during the actual pyrolysis. By observing optical and scanning electron microscope images, the morphology of the structures before and after pyrolysis was studied and the same patterns were also characterized by a laser probe profilometer. Finally, the thus obtained carbon patterns on Si wafers were used to carry out cell culture tests with Neural Stem Cells (NSC). The adhesion and the arrangement of the stem cells were analyzed to verify the ability of the patterned substrates to guide the orientation and, therefore, the differentiation of the cells