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The determination of stresses and material properties of polyimide coatings and films using real time holographic interferometry/
This dissertation presents a new technique for determining the residual stresses and material properties of polyimide coatings. The primary materials studied are polyimides, pyromellitic dianhydride-oxydianiline (PMDA-ODA) and poly (N,N\sp\prime(phenylene)-3,3\sp\prime4,4\sp\prime-biphenyl tetracarboxylic diimide) (BPDA-PDA). The determination of the internal stresses which develop during processing in these coatings is critical for reliability prediction and material selection for the microelectronics industry. For any given coating on a rigid substrate, the shear and normal tractions between the two materials goes to zero away from the edges. A portion of the substrate can therefore be removed leaving a simply supported membrane (coating) with its original state of stress intact. Classical vibration theory states that the square of the resonant frequency of a membrane is proportional to its biaxial stress. Real-time holographic interferometry is used to identify the resonant modes of vibration. It is also shown that using this technique the orthotropic axes of polymer films can be identified, thus simplifying the determination of all nine orthotropic elasticity coefficients
Comparison of MRI and DXA to measure muscle size and age-related atrophy in thigh muscles.
OBJECTIVES
Magnetic resonance imaging (MRI) and dual-energy x-ray absorptiometry (DXA) were used to examine the thigh lean mass in young and old men and women.
METHODS
A whole-body DXA scan was used to estimate thigh lean mass in young (20 men; 22.4±3.1y; 18 women; 22.1±2.0y) and older adults (25 men; 72.3±4.9y; 28 women; 72.0±4.5y). Thigh lean mass determined with a thigh scan on the DXA or full thigh MRI scans were compared.
RESULTS
Although the thigh lean mass quantified by DXA and MRI in young and older participants were correlated (R(2)=0.88; p<0.001) the magnitude of the differences in thigh lean mass between young and old was smaller with DXA than MRI (old vs. young men 79.5±13.1% and 73.4±11.2%; old vs. young women 88.6±11.8% and 79.4±12.3%, respectively). Detailed analysis of MRI revealed 30% smaller quadriceps muscles in the older than young individuals, while the other thigh muscles were only 18% smaller.
CONCLUSIONS
DXA underestimates the age-related loss of thigh muscle mass in comparison to MRI. The quadriceps muscles were more susceptible to age-related atrophy compared with other thigh muscles
A comprehensive study of noble gases and nitrogen in Hypatia, a diamond-rich pebble from SW Egypt
This is a follow-up study of a work by Kramers et al. (2013) on an unusual
diamond-rich rock found in the SW side of the Libyan Desert Glass strewn field.
This pebble, called Hypatia, is composed of almost pure carbon. Transmission
Electron Microscopy and X-ray diffraction results reveal that Hypatia is made
of defect-rich diamond containing lonsdaleite and deformation bands. These
characteristics are compatible with an impact origin on Earth and/or in space.
We analyzed concentrations and isotopic compositions of all five noble gases
and nitrogen in several mg sized Hypatia samples. These data confirm that
Hypatia is extra-terrestrial. The sample is rich in trapped noble gases with an
isotopic composition close to the meteoritic Q component. 40Ar/36Ar ratios in
individual steps are as low as 0.4. Concentrations of cosmic-ray produced 21Ne
correspond to a nominal cosmic-ray exposure age of ca. 0.1 Myr if produced in a
typical m-sized meteoroid. Such an atypically low nominal exposure age suggests
high shielding in a considerably larger body. In addition to the Xe-Q
composition, an excess of radiogenic 129Xe (from the decay of extinct 129I) is
observed (129Xe/132Xe = 1.18 +/- 0.03). Two N components are present, an
isotopically heavy component ({\delta}15N = +20 permil) released at low temp.
and a major light component ({\delta}15N = -110 permil) at higher temp. This
disequilibrium in N suggests that the diamonds in Hypatia were formed in space.
Our data are broadly consistent with concentrations and isotopic compositions
of noble gases in at least three different types of carbon-rich meteoritic
materials. However, Hypatia does not seem to be related to any of these
materials, but may have sampled a similar cosmochemical reservoir. Our study
does not confirm the presence of exotic noble gases that led Kramers et al. to
propose that Hypatia is a remnant of a comet that impacted the Earth
The next step of the word problem over monoids
It is known that a group presentation P can be regarded as a 2-complex with a single 0-cell. Thus we can consider a 3-complex with a single 0-cell which is known as a 3-presentation. Similarly, we can also consider 3-presentations for monoids. In this paper, by using spher- ical monoid pictures, we show that there exists a finite 3-monoid-presentation which has unsolvable ‘‘generalized identity problem’’ that can be thought as the next step (or one- dimension higher) of the word problem for monoids. We note that the method used in this paper has chemical and physical applications
<sup>14</sup>C AMS at SUERC: improving QA data from the 5 MV tandem AMS and 250 kV SSAMS
In 2003, a National Electrostatics Corporation (NEC) 5MV tandem accelerator mass spectrometer was installed at SUERC, providing the radiocarbon laboratory with 14C measurements to 4–5‰ repeatability. In 2007, a 250kV single-stage accelerator mass spectrometer (SSAMS) was added to provide additional 14C capability and is now the preferred system for 14C analysis. Changes to the technology and to our operations are evident in our copious quality assurance data: typically, we now use the 134-position MC-SNICS source, which is filled to capacity. Measurement of standards shows that spectrometer running without the complication of on-line δ13C evaluation is a good operational compromise. Currently, 3‰ 14C/13C measurements are routinely achieved for samples up to nearly 3 half-lives old by consistent sample preparation and an automated data acquisition algorithm with sample random access for measurement repeats. Background and known-age standard data are presented for the period 2003–2008 for the 5MV system and 2007–2008 for the SSAMS, to demonstrate the improvements in data quality
The influence of patellar tendon and muscle-tendon unit stiffness on quadriceps explosive strength in man
What is the central question of this study?
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Do tendon and/or muscle–tendon unit stiffness influence rate of torque development?
What is the main finding and its importance?
In our experimental conditions, some measures of relative (to maximal voluntary torque and tissue length) muscle–tendon unit stiffness had small correlations with voluntary/evoked rate of torque development over matching torque increments. However, absolute and relative tendon stiffness were unrelated to voluntary and evoked rate of torque development. Therefore, the muscle aponeurosis but not free tendon influences the relative rate of torque development. Factors other than tissue stiffness more strongly determine the absolute rate of torque development.
The influence of musculotendinous tissue stiffness on contractile rate of torque development (RTD) remains opaque. In this study, we examined the relationships between both patellar tendon (PT) and vastus lateralis muscle–tendon unit (MTU) stiffness and the voluntary and evoked knee-extension RTD. Fifty-two healthy untrained men completed duplicate laboratory sessions. Absolute and relative RTD were measured at 50 N m or 25% maximal voluntary torque (MVT) increments from onset and sequentially during explosive voluntary and evoked octet isometric contractions (supramaximal stimulation; eight pulses at 300 Hz). Isometric MVT was also assessed. Patellar tendon and MTU stiffness were derived from simultaneous force and ultrasound recordings of the PT and vastus lateralis aponeurosis during constant RTD ramp contractions. Absolute and relative (to MVT and resting tissue length) stiffness (k) was measured over identical torque increments as RTD. Pearson's correlations tested relationships between stiffness and RTD measurements over matching absolute/relative torque increments. Absolute and relative PT k were unrelated to equivalent voluntary/evoked (r = 0.020–0.255, P = 0.069–0.891). Absolute MTU k was unrelated to voluntary or evoked RTD (r ≤ 0.191, P ≥ 0.184), but some measures of relative MTU k were related to relative voluntary/evoked RTD (e.g. RTD for 25–50% MVT, r = 0.374/0.353, P = 0.007/0.014). In conclusion, relative MTU k explained a small proportion of the variance in relative voluntary and evoked RTD (both ≤19%), despite no association of absolute MTU k or absolute/relative PT k with equivalent RTD measures. Therefore, the muscle-aponeurosis component but not free tendon was associated with relative RTD, although it seems that an overriding influence of MVT negated any relationship of absolute MTU k and absolute RTD
Training-specific functional, neural, and hypertrophic adaptations to explosive- vs. sustained-contraction strength training
Training specificity is considered important for strength training, although the functional and underpinning physiological adaptations to different types of training, including brief explosive contractions, are poorly understood. This study compared the effects of 12 wk of explosive-contraction (ECT, n = 13) vs. sustained-contraction (SCT, n = 16) strength training vs. control (n = 14) on the functional, neural, hypertrophic, and intrinsic contractile characteristics of healthy young men. Training involved 40 isometric knee extension repetitions (3 times/wk): contracting as fast and hard as possible for ∼1 s (ECT) or gradually increasing to 75% of maximum voluntary torque (MVT) before holding for 3 s (SCT). Torque and electromyography during maximum and explosive contractions, torque during evoked octet contractions, and total quadriceps muscle volume (QUADSVOL) were quantified pre and post training. MVT increased more after SCT than ECT [23 vs. 17%; effect size (ES) = 0.69], with similar increases in neural drive, but greater QUADSVOL changes after SCT (8.1 vs. 2.6%; ES = 0.74). ECT improved explosive torque at all time points (17-34%; 0.54 ≤ ES ≤ 0.76) because of increased neural drive (17-28%), whereas only late-phase explosive torque (150 ms, 12%; ES = 1.48) and corresponding neural drive (18%) increased after SCT. Changes in evoked torque indicated slowing of the contractile properties of the muscle-tendon unit after both training interventions. These results showed training-specific functional changes that appeared to be due to distinct neural and hypertrophic adaptations. ECT produced a wider range of functional adaptations than SCT, and given the lesser demands of ECT, this type of training provides a highly efficient means of increasing function
COVID-19 patients require multi-disciplinary rehabilitation approaches to address persisting symptom profiles and restore pre-COVID quality of life
Long-COVID diagnosis is prominent, and our attention must support those experiencing debilitating and long-standing symptoms. To establish patient pathways, we must consider the societal and economic impacts of sustained COVID-19. Accordingly, we sought to determine the pertinent areas impacting quality of life (QoL) following a COVID-19 infection. Three hundred and eighty-one participants completed a web-based survey (83% female, 17% male) consisting of 70 questions across 7 sections (demographics, COVID-19 symptoms; QoL; sleep quality; breathlessness; physical activity and mental health). Mean age, height, body mass and body mass index (BMI) were 42 ± 12 years, 167.6 ± 10.4 cm, 81.2 ± 22.2 kg, and 29.1 ± 8.4 kg.m2, respectively. Participant health was reduced because of COVID-19 symptoms (“Good health” to “Poor health” [P<0.001]). Survey respondents who work reported ongoing issues with performing moderate (83%) and vigorous (79%) work-related activities.
COVID-19 patients report reduced capacity to participate in activities associated with daily life, including employment activities. Bespoke COVID-19 support pathways must consider multi-disciplinary approaches that address the holistic needs of patients to restore pre-pandemic quality of life and address experienced health and wellbeing challenges
Treatment of complete urethral obstruction by using pneumatic lithotripsy in a dog: a preliminary report
Tendinous tissue adaptation to explosive- vs. sustained-contraction strength training
© 2018 Massey, Balshaw, Maden-Wilkinson, Tillin and Folland. The effect of different strength training regimes, and in particular training utilizing brief explosive contractions, on tendinous tissue properties is poorly understood. This study compared the efficacy of 12 weeks of knee extensor explosive-contraction (ECT; n = 14) vs. sustained-contraction (SCT; n = 15) strength training vs. a non-training control (n = 13) to induce changes in patellar tendon and knee extensor tendon-aponeurosis stiffness and size (patellar tendon, vastus-lateralis aponeurosis, quadriceps femoris muscle) in healthy young men. Training involved 40 isometric knee extension contractions (three times/week): gradually increasing to 75% of maximum voluntary torque (MVT) before holding for 3 s (SCT), or briefly contracting as fast as possible to ~80% MVT (ECT). Changes in patellar tendon stiffness and Young's modulus, tendon-aponeurosis complex stiffness, as well as quadriceps femoris muscle volume, vastus-lateralis aponeurosis area and patellar tendon cross-sectional area were quantified with ultrasonography, dynamometry, and magnetic resonance imaging. ECT and SCT similarly increased patellar tendon stiffness (20% vs. 16%, both p < 0.05 vs. control) and Young's modulus (22% vs. 16%, both p < 0.05 vs. control). Tendon-aponeurosis complex high-force stiffness increased only after SCT (21%; p < 0.02), while ECT resulted in greater overall elongation of the tendon-aponeurosis complex. Quadriceps muscle volume only increased after sustained-contraction training (8%; p = 0.001), with unclear effects of strength training on aponeurosis area. The changes in patellar tendon cross-sectional area after strength training were not appreciably different to control. Our results suggest brief high force muscle contractions can induce increased free tendon stiffness, though SCT is needed to increase tendon-aponeurosis complex stiffness and muscle hypertrophy
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