634 research outputs found

    Is First, They Killed My Father a Cambodian testimonio?

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    In his article Is First, They Killed My Father a Cambodian testimonio John T. Maddox discusses aspects of the testimonial. Dialoguing with leading Latin Americanists, Maddox argues that Cambodian writer Loung Ung\u27s First, They Killed My Father (2000) challenges this uniqueness and opens studies on the testimonio to new possibilities for intellectual reflection and political activism. In Maddox\u27s view, the continued use of the term testimonio would serve as a reference to this long-standing tradition of writing and thinking about political violence in Latin America. After a discussion of the debate of the definition and function of testimonio and a synopsis of Ung\u27s work, Maddox argues that the ongoing intellectual debates regarding the testimonio, its form, its place in the literary canon, and its role in politics among Latin Americanists can also be applied to the work

    Anthony F. Mira (1820-85)

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    Anthony F, Mira was a Master Baker, He lived at 505 E. President Street in Lot Number 21 or the Green Ward, Anthony F, Mira was a illustrious businessman and devoted family man, Anthony F, Mira had a deep interest for politics and even ran for office once.https://digitalcommons.georgiasouthern.edu/sav-bios-lane/1196/thumbnail.jp

    A Presynaptic Role for Nitric Oxide at a GABAergic Synapse

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    Amacrine cells are a class of retinal interneurons that process the visual signal in the inner retina. Several subtypes of amacrine cells express nitric oxide synthase and produce nitric oxide (NO), making NO a possible regulator of amacrine cell function. My dissertation research tests the hypothesis that NO alters amacrine cell GABAergic synaptic output. To investigate this, I made whole-cell voltage clamp recordings of cultured chick amacrine cells receiving synaptic input from other amacrine cells and Ca2+ imaging of amacrine cell dendrites, which can be presynaptic. I find that NO-dependent increases in GABAergic spontaneous postsynaptic current (sPSC) frequency are independent of soluble guanylate cyclase and action potentials. Removal of extracellular Ca2+ and buffering of cytosolic Ca2+ both inhibit the response to NO. In Ca2+ imaging experiments, I confirm that NO increases dendritic Ca2+ by activating a Ca2+ influx pathway. Neither NO-dependent dendritic Ca2+ elevation nor increase in sPSC frequency are dependent upon Ca2+ release from stores. NO also enhances evoked GABAergic responses, and because voltage-gated Ca2+ channel function is not altered by NO, the enhanced evoked release is likely due to the combination of voltage-dependent Ca2+ influx and the voltage-independent, NO-dependent Ca2+ influx. Insight into the identity of the Ca2+ channel involved in the NO response was provided by characteristics unique to the transient receptor potential canonical (TRPC) channel subunits 4 and 5: the NO-dependent increase in sPSC frequency was dependent on downstream activity of PLC, blocked by 2 mM La3+ and enhanced by 10 µM La3+. The TRPC inhibitor ML204, which preferentially blocks TRPC4, had no effect on the NO response at 10 µM, but 20 µM ML204 blocked the NO response. The TRPC inhibitor clemizole, which preferentially blocks TRPC5, blocked NO-dependent dendritic Ca2+ elevations and the increase in sPSC frequency. Genetic knockdown of TRPC5 in cultured amacrine cells using the CRISPR/Cas9 system confirms that TRPC5 mediates NO-dependent dendritic Ca2+ elevations and the increase in sPSC frequency. These results suggest that NO-dependent activation of TRPC5 at amacrine cell presynaptic sites will enhance vesicular GABA release and increase inhibition onto postsynaptic cells

    Palaeoenvironments, stratigraphy and tectonics of parts of the Asbian and Brigantian succession in Fife and the Lothians (eastern part of the Midland Valley of Scotland)

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    SIGLEAvailable from British Library Document Supply Centre- DSC:DX84098 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

    John Ray Maddox, Jr. in a Senior Percussion Recital

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    This is the program for the senior percussion recital of John Ray Maddox, Jr. The recital took place on November 19, 1968, in Mitchell Hall

    Coronel Delmiro Gouveia, Brazilian (Film) Industry, and World War I in the Sertão

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    In the film 'Coronel Delmiro Gouveia' (1978), Brazilian director Geraldo Sarno uses historical fiction about “'the coronel of coronéis'” to negotiate the limits of government censorship and discuss the domestic and international policies of the military dictatorship, including its relationship to the state cinema enterprise Embrafilme, through a portrayal of a progressive but authoritarian businessman of the 'sertão' who died in Brazil’s first global war of the twentieth century. The film is one of the few Brazilian films about the country’s oft-overlooked role in World War I. Close analysis of the work reveals Sarno’s deft use of allegory for social commentary on class conflict and the film industry. Resumen No filme 'Coronel Delmiro Gouveia' (1978), o diretor brasileiro Geraldo Sarno usa a ficção histórica sobre “o Coronel dos Coronéis” para negociar com os limites da censura do governamental e discutir a política doméstica e internacional da ditadura militar, inclusive sua relação com a empresa estatal cinematográfica Embrafilme, através da representação de um homem de negócios do sertão que era tanto progresista como autoritário. Ele morreu na primeira guerra global do Brasil no século XX. O filme é um dos poucos que trata do papel do Brasil na Primeira Guerra Mundial, um fato pouco estudado. Um análise cauteloso da obra revela o uso destro de Sarno da alegoria para comentar sobre o conflito de classes e a indústria conematográfica
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