Buried Ion-Exchanged Glass Wavelengths: Burial-Depth Dependence on Waveguide Width

A detailed theoretical and experimental study of the depth dependence of buried ion-exchanged waveguides on waveguide width is reported. Modeling, which includes the effect of nonhomogeneous time-dependent electric field distribution, agrees well with our experiments showing that burial depth increases linearly with waveguide width. These results may be used in the proper design of integrated optical circuits that need waveguides of different widths at different sections, such as arrayed waveguide gratings

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles.

Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma. However, a possible role of these drugs in altering morphology and distribution of cholesterol particles is poorly understood. Here, we describe the in vitro evaluation of lipid-lowering drug effects in modulating morphological features of cholesterol particles using the plaque array method in combination with imaging flow cytometry. Image analyses of the cholesterol particles indicated that lovastatin, simvastatin, ezetimibe, and atorvastatin induce the formation of both globular and linear strand-shaped particles, whereas niacin, fibrates, fluvastatin, and rosuvastatin induce the formation of only globular-shaped particles. Next, purified very low-density lipoprotein (VLDL) and LDL particles incubated with these drugs showed changes in the morphology and image texture of cholesterol particles subpopulations. Furthermore, screening of 50 serum samples revealed the presence of a higher level of linear shaped HDL cholesterol particles in subjects with dyslipidemia (mean of 18.3%) compared to the age-matched normal (mean of 11.1%) samples. We also observed considerable variations in lipid-lowering drug effects on reducing linear shaped LDL and HDL cholesterol particles formation in serum samples. These findings indicate that lipid-lowering drugs, in addition to their cell-mediated hypolipidemic effects, may directly modulate morphology of cholesterol particles by a non-enzymatic mechanism of action. The outcomes of these results have potential to inform diagnosis of atherosclerosis and predict optimal lipid-lowering therapy

Hybrid Multicarrier Random Space Vector PWM for the Mitigation the Acoustic Noise

The pulse width modulation (PWM) inverter is obvious for any industrial and power sector application. Particularly industrial drives are very keen on the industrial standards. Many modulations approached such a drives objects of DC-link consumption, harmonics suppression in lower and higher order spectrum and noise reduction. The still random PWM is a best candidate for reducing the noises on the PWM operated AC drives. There are various Random PWM (RPWM) methods has been developed and investigated for the PWM inverter fed drive noise reductions, still the shortcomings are existence on these method items of their less randomness and complex digital circuitry. These PWM dealt the spreading harmonics there by decreasing harmonic effects on the system. However, these techniques overlook the effect of acoustic noise and DC -link utilizations Therefore, in this paper mainly deals with to combined RPWM principle in space vector PWM (SVPWM) to generate random PWM generation using asymmetric frequency multi carrier called multicarrier random space vector PWM (MCRSVPWM). The SVM agreements with multicarrier (different fixed frequencies as carrier waves) which are chosen with the aid of a random binary bit generator. The proposed RSVM generated pulses with a randomized triangular carrier (4 ± 1.5 kHz), while the conventional RPWM method contains of the random pulse position with a fixed frequency triangular carrier. The simulation study is performed through MATLAB/Simulink for 3 HP asynchronous induction motor drive. The Experimental validation of proposed MCRSVPWM is tested with 2kW six switch (Power MOSFET – SCH2080KE) inverter power module fed induction motor drive.publishedVersio

Neutral Point Clamped Transformerless Multilevel Converter for Grid-Connected Photovoltaic System

Transformer-less (TL) inverter topologies have elicited further special treatment in photo-voltaic (PV) power system as they provide high efficiency and low cost. Neutral point clamped (NPC) multilevel-inverter (MLI) topologies-based transformer-less are being immensely used in grid-connected medium-voltage high-power claims. Unfortunately, these topologies such as NPC-MLI, full-bridge inverter with DC bypass (FB-DCBP) suffer from the shoot-through problem on the bridge legs, which affect the reliability of the implementation. Based on the previous above credits, a T type neutral point clamped (TNP) - MLI (TNP-MLI) with Transformer-less topology called TL-TNP-MLI is presented to be an alternate which can be suitable in the grid connected PV power generation systems. The suggested TL-TNP-MLI topologies free from inverter bridge legs shoot-through burden, switching frequency common-mode current (CMC), and leakage current. The control system of the grid interface with hysteresis current control (HCC) strategy is proposed. The effectiveness of the proposed PV connected transformer-less TNP-MLI topology with different grid and PV scenario has been verified through the MATLAB/Simulink simulation model and field-programmable gate area (FPGA) based experimental results for a 1.5 kW system.publishedVersio

High nitrous oxide fluxes from rice indicate the need to manage water for both long- and short-term climate impacts

Global rice cultivation is estimated to account for 2.5% of current anthropogenic warming because of emissions of methane (CH4), a short-lived greenhouse gas. This estimate assumes a widespread prevalence of continuous flooding of most rice fields and hence does not include emissions of nitrous oxide (N2O), a long-lived greenhouse gas. Based on the belief that minimizing CH4 from rice cultivation is always climate beneficial, current mitigation policies promote increased use of intermittent flooding. However, results from five intermittently flooded rice farms across three agroecological regions in India indicate that N2O emissions per hectare can be three times higher (33 kg-N2O⋅ha−1⋅season−1) than the maximum previously reported. Correlations between N2O emissions and management parameters suggest that N2O emissions from rice across the Indian subcontinent might be 30–45 times higher under intensified use of intermittent flooding than under continuous flooding. Our data further indicate that comanagement of water with inorganic nitrogen and/or organic matter inputs can decrease climate impacts caused by greenhouse gas emissions up to 90% and nitrogen management might not be central to N2O reduction. An understanding of climate benefits/drawbacks over time of different flooding regimes because of differences in N2O and CH4 emissions can help select the most climate-friendly water management regimes for a given area. Region-specific studies of rice farming practices that map flooding regimes and measure effects of multiple comanaged variables on N2O and CH4 emissions are necessary to determine and minimize the climate impacts of rice cultivation over both the short term and long term

De novo assembly and transcriptome analysis of five major tissues of Jatropha curcas L. using GS FLX titanium platform of 454 pyrosequencing

<p>Abstract</p> <p>Background</p> <p><it>Jatropha curcas </it>L. is an important non-edible oilseed crop with promising future in biodiesel production. However, factors like oil yield, oil composition, toxic compounds in oil cake, pests and diseases limit its commercial potential. Well established genetic engineering methods using cloned genes could be used to address these limitations. Earlier, 10,983 unigenes from Sanger sequencing of ESTs, and 3,484 unique assembled transcripts from 454 pyrosequencing of uncloned cDNAs were reported. In order to expedite the process of gene discovery, we have undertaken 454 pyrosequencing of normalized cDNAs prepared from roots, mature leaves, flowers, developing seeds, and embryos of <it>J. curcas</it>.</p> <p>Results</p> <p>From 383,918 raw reads, we obtained 381,957 quality-filtered and trimmed reads that are suitable for the assembly of transcript sequences. <it>De novo </it>contig assembly of these reads generated 17,457 assembled transcripts (contigs) and 54,002 singletons. Average length of the assembled transcripts was 916 bp. About 30% of the transcripts were longer than 1000 bases, and the size of the longest transcript was 7,173 bases. BLASTX analysis revealed that 2,589 of these transcripts are full-length. The assembled transcripts were validated by RT-PCR analysis of 28 transcripts. The results showed that the transcripts were correctly assembled and represent actively expressed genes. KEGG pathway mapping showed that 2,320 transcripts are related to major biochemical pathways including the oil biosynthesis pathway. Overall, the current study reports 14,327 new assembled transcripts which included 2589 full-length transcripts and 27 transcripts that are directly involved in oil biosynthesis.</p> <p>Conclusion</p> <p>The large number of transcripts reported in the current study together with existing ESTs and transcript sequences will serve as an invaluable genetic resource for crop improvement in jatropha. Sequence information of those genes that are involved in oil biosynthesis could be used for metabolic engineering of jatropha to increase oil content, and to modify oil composition.</p

A Simple Multilevel Space Vector Modulation Technique and MATLAB System Generator Built FPGA Implementation for Three-Level Neutral-Point Clamped Inverter

The pulse width modulation (PWM) is an important segment in power electronic inverters and multilevel inverters (MLIs) design. The space vector modulation (SVM) methods own distinct advantages over other PWM methods. However, MLI SVM has involved more mathematics in their executions. Hence, the digital signal processors (DSPs) or field programmable gate arrays (FPGAs) based digital implementations are highly preferred for MLI SVM realizations, which require exceptional properties. The conventional MLI SVMs use complex mathematical functions to solve their internal functions to identify the space vector diagram (SVD) sub-triangle and over modulation boundary switching on-times. Particularly these are the changes in the position of reference vector with respect to their sub-triangle positions involving higher mathematical functions. This paper proposes a simplified three-level MLI SVM that reduces the sub-triangle and over modulation switching on-time calculations with reduced mathematical functions. The proposed MLI SVM is derived based on two-level SVM without changing the reference vector position, unlike the traditional approaches. This helps in extending the SVM for any n-level inverter with additional LUTs. The detailed theoretical study, MATLAB-Simulink system generator simulations and Xilinx FPGA family SPARTAN-III-3A based experimental implementations are done with three-level neutral point MLI fed induction motor drive. The theoretical design, analysis, and experimentation results validate the advantages of the proposed PWM design and its implementation. In addition, the proposed implementation is executed from the MATLAB Xilinx system generator directly into target FPGA, which makes it faithful, efficient and minimizes the time spent

Hybrid Multicarrier Random Space Vector PWM for the Mitigation of Acoustic Noise

The pulse width modulation (PWM) inverter is an obvious choice for any industrial and power sector application. Particularly, industrial drives benefit from the higher DC-link utilization, acoustic noise, and vibration industrial standards. Many PWM techniques have been proposed to meet the drives’ demand for higher DC-link utilization and lower harmonics suppression and noise reductions. Still, random PWM (RPWM) is the best candidate for reducing the acoustic noises. Few RPWM (RPWM) methods have been developed and investigated for the AC drive’s PWM inverter. However, due to the lower randomness of the multiple frequency harmonics spectrum, reducing the drive noise is still challenging. These PWMs dealt with the spreading harmonics, thereby decreasing the harmonic effects on the system. However, these techniques are unsuccessful at maintaining the higher DC-link utilizations. Existing RPWM methods have less randomness and need complex digital circuitry. Therefore, this paper mainly deals with a combined RPWM principle in space vector PWM (SVPWM) to generate random PWM generation using an asymmetric frequency multicarrier called multicarrier random space vector PWM (MCRSVPWM). he SVPWM switching vectors with different frequency carrier are chosen with the aid of a random bi-nary bit generator. The proposed MCRSVPWM generates the pulses with a randomized triangular carrier (1 to 4 kHz), while the conventional RPWM method contains a random pulse position with a fixed frequency triangular carrier. The proposed PWM is capable of eradicating the high-frequency unpleasant acoustic noise more effectually than conventional RPWM with a shorter random frequency range. The simulation study is performed through MATLAB/Simulink for a 2 kW asynchronous induction motor drive. Experimental validation of the proposed MCRSVPWM is tested with a 2 kW six-switch (Power MOSFET–SCH2080KE) inverter power module-fed induction motor drive