Enhancing Data Warehouse management through semi-automatic data integration and complex graph generation

2013 - 2014Strategic information is one of the main assets for many organizations and, in the next future, it will become increasingly more important to enable the decisionmakers answer questions about their business, such as how to increase their profitability. A proper decision-making process is benefited by information that is frequently scattered among several heterogeneous databases. Such databases may come from several organization systems and even from external sources. As a result, organization managers have to deal with the issue of integrating several databases from independent data sources containing semantic differences and no specific or canonical concept description. Data Warehouse Systems were born to integrate such kind of heterogeneous data in order to be successively extracted and analyzed according to the manager’s needs and business plans. Besides being difficult and onerous to design, integrate and build, Data Warehouse Systems present another issue related to the difficulty to represent multidimensional information typical of the result of OLAP operations, such as aggregations on data cubes, extraction of sub-cubes or rotations of the data axis, through easy to understand views... [edited by author]XIII n.s

model checking for data anomaly detection

Abstract Data tipically evolve according to specific processes, with the consequent possibility to identify a profile of evolution: the values it may assume, the frequencies at which it changes, the temporal variation in relation to other data, or other constraints that are directly connected to the reference domain. A violation of these conditions could be the signal of different menaces that threat the system, as well as: attempts of a tampering or a cyber attack, a failure in the system operation, a bug in the applications which manage the life cycle of data. To detect such violations is not straightforward as processes could be unknown or hard to extract. In this paper we propose an approach to detect data anomalies. We represent data user behaviours in terms of labelled transition systems and through the model checking techniques we demonstrate the proposed modeling can be exploited to successfully detect data anomalies

Extracellular cyclophilin-A stimulates ERK1/2 phosphorylation in a cell-dependent manner but broadly stimulates nuclear factor kappa B

<p>Abstract</p> <p>Background</p> <p>Although the peptidyl-prolyl isomerase, cyclophilin-A (peptidyl-prolyl isomerase, PPIA), has been studied for decades in the context of its intracellular functions, its extracellular roles as a major contributor to both inflammation and multiple cancers have more recently emerged. A wide range of activities have been ascribed to extracellular PPIA that include induction of cytokine and matrix metalloproteinase (MMP) secretion, which potentially underlie its roles in inflammation and tumorigenesis. However, there have been conflicting reports as to which particular signaling events are under extracellular PPIA regulation, which may be due to either cell-dependent responses and/or the use of commercial preparations recently shown to be highly impure.</p> <p>Methods</p> <p>We have produced and validated the purity of recombinant PPIA in order to subject it to a comparative analysis between different cell types. Specifically, we have used a combination of multiple methods such as luciferase reporter screens, translocation assays, phosphorylation assays, and nuclear magnetic resonance to compare extracellular PPIA activities in several different cell lines that included epithelial and monocytic cells.</p> <p>Results</p> <p>Our findings have revealed that extracellular PPIA activity is cell type-dependent and that PPIA signals via multiple cellular receptors beyond the single transmembrane receptor previously identified, Extracellular Matrix MetalloPRoteinase Inducer (EMMPRIN). Finally, while our studies provide important insight into the cell-specific responses, they also indicate that there are consistent responses such as nuclear factor kappa B (NFκB) signaling induced in all cell lines tested.</p> <p>Conclusions</p> <p>We conclude that although extracellular PPIA activates several common pathways, it also targets different receptors in different cell types, resulting in a complex, integrated signaling network that is cell type-specific.</p

The Current State of Industrial Production in the European Union and New Recovery Solutions

Industrial activity is of great importance in the economic development of all countries, but in the last decades the results of this branch of the economies of many countries have faced various problems due to the systemic crises that economies in transition, but also the economies of developed countries, are going through. In this article, we propose to review some aspects of the situation regarding industrial production in EU countries, with a stronger focus on industrial production in Romania. It is more necessary to study these topics considering the crisis of the Covid-19 Pandemic, the geopolitical crisis in the region that has stopped multiple logistic processes related to the industry. In other words, it is important to connect the industrial strategies and policies of the European Union countries for the development of Industry 4.0/5.0, to digitize production systems, digital technological processes and robotization, efficient management of the production and distribution chain. We propose to outline the main objectives that must be taken into account for the development of new industrial policies focused on new directions of development for the Romanian economy

The Evaluation of Unincorporated Areas – Particularities and Perspectives on the Real Estate Market

The real estate market in Romania occupies an important position within the national economy, with the results in the real estate field having a significant impact on the determination of the macroeconomic indicators� values. We can consider that within each economy, the real estate market represents a complex sector, due to the high volume of carried out transactions and to the high number of individuals that take part in the carrying out of the transactions. The importance of area evaluation is guaranteed by the high number of its practical applications. The information provided by the evaluator is used by judicial institutions as a basis for various decision making processes

The Development and Study of Some Composite Membranes Based on Polyurethanes and Iron Oxide Nanoparticles

To improve the performance of composite membranes, their morphology can be tailored by precise control of the fabrication methods and processing conditions. To this end, the aim of this study was to develop novel high-performance composite membranes based on polyurethane matrix and magnetic nanoparticles with the desired morphology and stability, by selecting the proper method and fabrication systems. These well-prepared composite membranes were investigated from the point of view of their morphological, physico-chemical, mechanical, dielectric, and magnetic properties. In addition, their in vitro cytocompatibility was also verified by the MTT assay and their cell morphology. The results of this study can provide valuable information regarding the preparation of magnetic polyurethane-based composite membranes that could be used to design some suitable devices with tailored properties, in order to improve the image quality in magnetic resonance imaging investigations and to suppress local image artifacts and blurring

Study of physiological properties of some probiotics in multiple cultures with mesophilic lactic acid bacteria by Flora Danica Ch. Hansen commercial starter

The aim of this study was to establish the growth ability and stability of probiotic strains Lactobacillus acidophilus (commercial code La-5®), Lactobacillus casei ssp. paracasei (commercial code L. casei 431®) and Bifidobacterium bifidus (commercial code BB-12®) in multiple cultures with mesophilic lactic bacteria, Lactococcus lactis ssp. cremoris, Lactococcus lactis ssp. lactis, Lactococcus lactis ssp. diacetylactis and Leuconostoc mesenteroides spp. cremoris, as Flora Danica Chr. Hansen commercial starters. Under the controlled fermentative conditions described below, a good starter combination, for the high rate of cells multiplication and for the good viability during storage, was identified in the mixture of L. casei 431®, BB-12® and Flora Danica, in ratio of 1:1:1 (9 log CFU/mL for each starter culture)