376 research outputs found
Alien Registration- Macomber, Ethel M. (Portland, Cumberland County)
https://digitalmaine.com/alien_docs/22235/thumbnail.jp
The Fiscal Forensics of the Las Vegas Strip Lessons from the Financial Crisis
Hitting with the force of a 100-year storm, the first two years of the financial crisis caused a -1.6 billion. Other signs of recovery trickle in but are sporadic and volatile. This article is an attempt to disaggregate the variance and look at where Las Vegas has been, where it is now and how it got there to learn from this trying period and help manage the future
Adoption and Foster Care by Gay and Lesbian Parents in the United States
Discussion and debate about adoption and foster care by gay, lesbian, and bisexual (GLB) parents occurs frequently among child welfare policymakers, social service agencies, and social workers. They all need better information about GLB adoptive and foster parents and their children as they make individual and policy-level decisions about placement of children with GLB parents. This report provides new information on GLB adoption and foster care from the U.S. Census 2000, the National Survey of Family Growth (2002), and the Adoption and Foster Care Analysis and Reporting System (2004)
Is classical reality completely deterministic?
The concept of determinism for a classical system is interpreted as the
requirement that the solution to the Cauchy problem for the equations of motion
governing this system be unique. This requirement is generally assumed to hold
for all autonomous classical systems. We give counterexamples of this view. Our
analysis of classical electrodynamics in a world with one temporal and one
spatial dimension shows that the solution to the Cauchy problem with the
initial conditions of a particular type is not unique. Therefore, random
behavior of closed classical systems is indeed possible. This finding provides
a qualitative explanation of how classical strings can split. We propose a
modified path integral formulation of classical mechanics to include
indeterministic systems.Comment: Replace the paper with a revised versio
MRI radiomic features are independently associated with overall survival in soft tissue sarcoma
Purpose: Soft tissue sarcomas (STS) represent a heterogeneous group of diseases, and selection of individualized treatments remains a challenge. The goal of this study was to determine whether radiomic features extracted from magnetic resonance (MR) images are independently associated with overall survival (OS) in STS.
Methods and Materials: This study analyzed 2 independent cohorts of adult patients with stage II-III STS treated at center 1 (N = 165) and center 2 (N = 61). Thirty radiomic features were extracted from pretreatment T1-weighted contrast-enhanced MR images. Prognostic models for OS were derived on the center 1 cohort and validated on the center 2 cohort. Clinical-only (C), radiomics-only (R), and clinical and radiomics (C+R) penalized Cox models were constructed. Model performance was assessed using Harrell\u27s concordance index.
Results: In the R model, tumor volume (hazard ratio [HR], 1.5) and 4 texture features (HR, 1.1-1.5) were selected. In the C+R model, both age (HR, 1.4) and grade (HR, 1.7) were selected along with 5 radiomic features. The adjusted c-indices of the 3 models ranged from 0.68 (C) to 0.74 (C+R) in the derivation cohort and 0.68 (R) to 0.78 (C+R) in the validation cohort. The radiomic features were independently associated with OS in the validation cohort after accounting for age and grade (HR, 2.4;
Conclusions: This study found that radiomic features extracted from MR images are independently associated with OS when accounting for age and tumor grade. The overall predictive performance of 3-year OS using a model based on clinical and radiomic features was replicated in an independent cohort. Optimal models using clinical and radiomic features could improve personalized selection of therapy in patients with STS
Triplicity and Physical Characteristics of Asteroid (216) Kleopatra
To take full advantage of the September 2008 opposition passage of the M-type
asteroid (216) Kleopatra, we have used near-infrared adaptive optics (AO)
imaging with the W.M. Keck II telescope to capture unprecedented high
resolution images of this unusual asteroid. Our AO observations with the W.M.
Keck II telescope, combined with Spitzer/IRS spectroscopic observations and
past stellar occultations, confirm the value of its IRAS radiometric radius of
67.5 km as well as its dog-bone shape suggested by earlier radar observations.
Our Keck AO observations revealed the presence of two small satellites in orbit
about Kleopatra (see Marchis et al., 2008). Accurate measurements of the
satellite orbits over a full month enabled us to determine the total mass of
the system to be 4.64+/-0.02 10^18 Kg. This translates into a bulk density of
3.6 +/-0.4 g/cm3, which implies a macroscopic porosity for Kleopatra of ~
30-50%, typical of a rubble-pile asteroid. From these physical characteristics
we measured its specific angular momentum, very close to that of a spinning
equilibrium dumbbell.Comment: 35 pages, 3 Tables, 9 Figures. In press to Icaru
A New Look at the Volume and Outcome Relationship in Surgery for Colorectal Cancer
Purpose: Surgeon and hospital factors have a significant impact on treatment outcomes for colorectal cancer (CRC). Limited research has been done to assess cost and quality of treatment by surgeon-volume. We aim to identify the surgeon factors impacting cost and quality of surgical care for CRC.
Methods: The University HealthSystem Consortium database was queried for patients who underwent colon resection for cancer from 2008 to 2012. Patients were grouped by surgeon-volume. Outcomes of interest were postoperative complications, ICU admission, readmission rate, inpatient hospital length of stay (LOS) and direct hospital cost. Average surgeon-volume per year was categorized as high (\u3e6) or low (16) based on the distribution of surgeon-volume.
Results: 29,972 patients over age 18 were identified for inclusion. 25,426 underwent resection by high-volume surgeons (HVS) and 4,547 by low-volume surgeons (LVS). LVS were more likely to admit patients to the ICU than HVS (21% v 33%, p
Conclusions: Surgeons who perform greater than 6 colectomies per year for colon cancer are more likely to use laparoscopy, less likely to admit patients to the ICU, have lower complication and readmission rates, and shorter LOS. Hospital cost is significantly lower in patients operated on by high volume surgeons. As health care costs continue to escalate and health care reform efforts gain momentum, factors leading to high-quality, cost-effective care need to be identified
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