Potential of a Neutrino Detector in the ANDES Underground Laboratory for Geophysics and Astrophysics of Neutrinos

The construction of the Agua Negra tunnels that will link Argentina and Chile under the Andes, the world longest mountain range, opens the possibility to build the first deep underground labo- ratory in the Southern Hemisphere. This laboratory has the acronym ANDES (Agua Negra Deep Experiment Site) and its overburden could be as large as \sim 1.7 km of rock, or 4500 mwe, providing an excellent low background environment to study physics of rare events like the ones induced by neutrinos and/or dark matter. In this paper we investigate the physics potential of a few kiloton size liquid scintillator detector, which could be constructed in the ANDES laboratory as one of its possible scientific programs. In particular, we evaluate the impact of such a detector for the studies of geoneutrinos and galactic supernova neutrinos assuming a fiducial volume of 3 kilotons as a reference size. We emphasize the complementary roles of such a detector to the ones in the Northern Hemisphere neutrino facilities through some advantages due to its geographical location.Comment: 20 pages, 16 figures and 9 table

The value of cell-free circulating tumour DNA profiling in advanced non-small cell lung cancer (NSCLC) management

Liquid biopsy (LB) has boosted a remarkable change in the management of cancer patients by contributing to tumour genomic profiling. Plasma circulating cell-free tumour DNA (ctDNA) is the most widely searched tumour-related element for clinical application. Specifically, for patients with lung cancer, LB has revealed valuable to detect the diversity of targetable genomic alterations and to detect and monitor the emergence of resistance mechanisms. Furthermore, its non-invasive nature helps to overcome the difficulty in obtaining tissue samples, offering a comprehensive view about tumour diversity. However, the use of the LB to support diagnostic and therapeutic decisions still needs further clarification. In this sense, this review aims to provide a critical view of the clinical importance of plasma ctDNA analysis, the most widely applied LB, and its limitations while anticipating concepts that will intersect the present and future of LB in non-small cell lung cancer patients

Avaliação da resistência de variedades de mangueira Mangifera indica L., do BAG manga da Embrapa Mandioca e Fruticultura, ao fungo Coletotrichum gloeosporioides, Penz.).

O Brasil está entre os nove principais produtores de manga do mundo, com uma área de 67 mil hectares. Atualmente, a Tommy Atkins é a variedade mais produzida e a que possui a maior participação no volume comercializado no mundo, devido, principalmente, as suas características fenológicas e organolépticas

Vector Meson Production in Ultraperipheral Heavy Ion Collisions

The ultraperipheral heavy ion collisions (UPC's) are an important alternative to study the QCD dynamics until the next generation of $e^+e^-/ ep / eA$ colliders become reality. Due to the coherent action of all the protons in the nucleus, the electromagnetic field is very strong and the resulting flux of equivalent photons is large, which allows to study two-photon as well as photonuclear interactions at high energies. In this paper we present a brief review of the vector meson production in UPC's at high energies using the QCD color dipole approach to describe their photonuclear production and the perturbative QCD Pomeron (BFKL dynamics) to describe the double meson production in photon-photon process. Predictions for rates and integrated cross sections are presented for energies of RHIC and LHC.Comment: 16 pages, 1 figure. Version to be published in Journal of Physics G: Nuclear and Particle Physic

SOLUTION OF MULTIPHASE HEAT CONDUCTION PROBLEMS VIA THE GENERALIZED INTEGRAL TRANSFORM TECHNIQUE WITH DOMAIN CHARACTERIZATION THROUGH THE INDICATOR FUNCTION

The Generalized Integral Transform Technique (GITT) has appeared in the literature as an alternative to conventional discrete numerical methods for partial differential equations in heat transfer and fluid flow. This method permits the automatic control of the error and is easy to program, since there is no need for a discretization. The method has being constantly improved, but there still a vast number of practical problems that has not being solved satisfactory. In several brands of engineering, the transport equations have to be solved for a combination of different phases or materials or inside irregular domains. In this case, the mathematical resource of the Indicator Function can be employed. This function is a representation of the phases or parts of the domain with the numbers 0 and 1 for each phase. According to the method, the Indicator Function is defined by Poisson’s equation, which is added to the system of the transport equations. An integral is done along the curve that defines the interface that will generate the source term in Poisson’ equation used to calculate the Indicator Function distribution. The solution of the system of equations is done using the common GITT approach. Then, an analytical expression for each transformed potential of the indicator function and the other variables are available. Once the transformed potentials are known, the Indicator Function can be analytically operated, and the interface can be represented by an analytical continuous function. In this work, the use of the GITT in conjunction with the Indicator Function is proposed. The methodology is described and some previous results are presented. GITT is applied to a two-dimensional heat conduction problem in a multiphase domain with an irregular geometry, inside a square domain. The methodology presented here can be extended to all brands of convection-diffusion problems already solved via GITT

Lagrangian formulation of classical fields within Riemann-Liouville fractional derivatives

The classical fields with fractional derivatives are investigated by using the fractional Lagrangian formulation.The fractional Euler-Lagrange equations were obtained and two examples were studied.Comment: 9 page

Probing QCD dynamics in two-photon interactions at high energies

In this paper the two-photon interactions at high energies are investigated considering different approaches for the QCD dynamics. In particular, we calculate the $\gamma^* \gamma^*$ total cross section in different theoretical approches and present a comparison among the predictions of the BFKL dynamics at leading and next-to-leading order with those from saturation physics. We analyze the possibility that the future linear colliders could discriminate between these different approaches.Comment: 14 pages, 2 figures. Version to be published in Journal of Physics G: Nuclear and Particle Physic

The Seyfert Population in the Local Universe

The magnitude-limited catalog of the Southern Sky Redshift Survey (SSRS2), is used to characterize the properties of galaxies hosting Active Galactic Nuclei. Using emission-line ratios, we identify a total of 162 (3%) Seyfert galaxies out of the parent sample with 5399 galaxies. The sample contains 121 Seyfert 2 galaxies and 41 Seyfert 1. The SSRS2 Seyfert galaxies are predominantly in spirals of types Sb and earlier, or in galaxies with perturbed appearance as the result of strong interactions or mergers. Seyfert galaxies in this sample are twice as common in barred hosts than the non-Seyferts. By assigning galaxies to groups using a percolation algorithm we find that the Seyfert galaxies in the SSRS2 are more likely to be found in binary systems, when compared to galaxies in the SSRS2 parent sample. However, there is no statistically significant difference between the Seyfert and SSRS2 parent sample when systems with more than 2 galaxies are considered. The analysis of the present sample suggests that there is a stronger correlation between the presence of the AGN phenomenon with internal properties of galaxies (morphology, presence of bar, luminosity) than with environmental effects (local galaxy density, group velocity dispersion, nearest neighbor distance).Comment: 35 pages, 13 figures, Accepted to be publised in Astronomical Journa