Neonatal weight loss in breast and formula-fed infants

We have observed an increase in the number of breast fed babies presenting with dehydration and/or failure to thrive because of lactation failure and non-recognition of feeding problems. Recent reports1,2 support this experience and recommend monitoring of the weight of infants through the neonatal period. However, these reports acknowledge uncertainty as to what actually constitutes normal neonatal weight loss. Maisels and colleagues published two studies which have been quoted as giving guidance on normal loss. Both studies were designed primarily to study factors that influence breast milk jaundice. The first3 reported a mean weight loss of about 6% in 100 unselected well babies during the first 3 days. The subsequent study4 reported a mean weight loss of 6.86% in 186 infants. The timescale over which babies were weighed was not clearly indicated, although it may have only been 2-3 days. The sample was neither population based nor randomly selected, being largely preselected because of the presence of more pronounced jaundice. The distribution of data points for early neonatal weight loss are likely to be skewed, yet both studies reported the results as mean (SD). Owing to the design and method of data presentation, these studies cannot reliably inform the debate as to what constitutes the norm. Marchini and colleagues published reports also designed primarily to study other issues. One5 indicated a mean early weight loss of 5.7%. Measurements were recorded over a three day period, and no indication is given of the skewness of the data. Another study6 reported a median weight loss of about 6% recorded over a four day period. At least one baby lost > 15% of his/her birth weight during this time, but there is no clear information as to the frequency with which more extreme degrees of weight loss are observed

Noise properties of two single electron transistors coupled by a nanomechanical resonator

We analyze the noise properties of two single electron transistors (SETs) coupled via a shared voltage gate consisting of a nanomechanical resonator. Working in the regime where the resonator can be treated as a classical system, we find that the SETs act on the resonator like two independent heat baths. The coupling to the resonator generates positive correlations in the currents flowing through each of the SETs as well as between the two currents. In the regime where the dynamics of the resonator is dominated by the back-action of the SETs, these positive correlations can lead to parametrically large enhancements of the low frequency current noise. These noise properties can be understood in terms of the effects on the SET currents of fluctuations in the state of a resonator in thermal equilibrium which persist for times of order the resonator damping time.Comment: Accepted for publication in Phys. Rev.

Fully Frustrated Cold Atoms

Fully frustrated Josephson Junction arrays (FF-JJA's) exhibit a subtle compound phase transition in which an Ising transition associated with discrete broken translational symmetry and a Berezinskii-Kosterlitz-Thouless (BKT) transition associated with quasi-long-range phase coherence occur nearly simultaneously. In this Letter we discuss a cold atom realization of the FF-JJA system. We demonstrate that both orders can be studied by standard momentum-distribution-function measurements and present numerical results, based on a successful self-consistent spin-wave approximation, that illustrate the expected behavior of observables.Comment: 5 pages, 3 figures, submitte

Some Properties of the Calogero-Sutherland Model with Reflections

We prove that the Calogero-Sutherland Model with reflections (the BC_N model) possesses a property of duality relating the eigenfunctions of two Hamiltonians with different coupling constants. We obtain a generating function for their polynomial eigenfunctions, the generalized Jacobi polynomials. The symmetry of the wave-functions for certain particular cases (associated to the root systems of the classical Lie groups B_N, C_N and D_N) is also discussed.Comment: 16 pages, harvmac.te

Renormalised four-point coupling constant in the three-dimensional O(N) model with N=0

We simulate self-avoiding walks on a cubic lattice and determine the second virial coefficient for walks of different lengths. This allows us to determine the critical value of the renormalized four-point coupling constant in the three-dimensional N-vector universality class for N=0. We obtain g* = 1.4005(5), where g is normalized so that the three-dimensional field-theoretical beta-function behaves as \beta(g) = - g + g^2 for small g. As a byproduct, we also obtain precise estimates of the interpenetration ratio Psi*, Psi* = 0.24685(11), and of the exponent \nu, \nu = 0.5876(2).Comment: 16 page

Description of Pairing correlation in Many-Body finite systems with density functional theory

Different steps leading to the new functional for pairing based on natural orbitals and occupancies proposed in ref. [D. Lacroix and G. Hupin, arXiv:1003.2860] are carefully analyzed. Properties of quasi-particle states projected onto good particle number are first reviewed. These properties are used (i) to prove the existence of such a functional (ii) to provide an explicit functional through a 1/N expansion starting from the BCS approach (iii) to give a compact form of the functional summing up all orders in the expansion. The functional is benchmarked in the case of the picked fence pairing Hamiltonian where even and odd systems, using blocking technique are studied, at various particle number and coupling strength, with uniform and random single-particle level spacing. In all cases, a very good agreement is found with a deviation inferior to 1% compared to the exact energy.Comment: 14 pages, 9 figure

Nanoscale Torsional Optomechanics

Optomechanical transduction is demonstrated for nanoscale torsional resonators evanescently coupled to optical microdisk whispering gallery mode resonators. The on-chip, integrated devices are measured using a fully fiber-based system, including a tapered and dimpled optical fiber probe. With a thermomechanically calibrated optomechanical noise floor down to 7 fm/sqrt(Hz), these devices open the door for a wide range of physical measurements involving extremely small torques, as little as 4x10^-20 N*m.Comment: 4 pages, 4 figures - Accepted to APL Oct 22nd, 2012. To appear in February 4th issue - as cover articl

Observability of counterpropagating modes at fractional-quantum-Hall edges

When the bulk filling factor is equal to 1 - 1/m with m odd, at least one counterpropagating chiral collective mode occurs simultaneously with magnetoplasmons at the edge of fractional-quantum-Hall samples. Initial experimental searches for an additional mode were unsuccessful. In this paper, we address conditions under which its observation should be expected in experiments where the electronic system is excited and probed by capacitive coupling. We derive realistic expressions for the velocity of the slow counterpropagating mode, starting from a microscopic calculation which is simplified by a Landau-Silin-like separation between long-range Hartree and residual interactions. The microscopic calculation determines the stiffness of the edge to long-wavelength neutral excitations, which fixes the slow-mode velocity, and the effective width of the edge region, which influences the magnetoplasmon dispersion.Comment: 18 pages, RevTex, 6 figures, final version to be published in Physical Review

Exact Dynamical Correlation Functions of Calogero-Sutherland Model and One-Dimensional Fractional Statistics

One-dimensional model of non-relativistic particles with inverse-square interaction potential known as Calogero-Sutherland Model (CSM) is shown to possess fractional statistics. Using the theory of Jack symmetric polynomial the exact dynamical density-density correlation function and the one-particle Green's function (hole propagator) at any rational interaction coupling constant $\lambda = p/q$ are obtained and used to show clear evidences of the fractional statistics. Motifs representing the eigenstates of the model are also constructed and used to reveal the fractional {\it exclusion} statistics (in the sense of Haldane's ``Generalized Pauli Exclusion Principle''). This model is also endowed with a natural {\it exchange } statistics (1D analog of 2D braiding statistics) compatible with the {\it exclusion} statistics. (Submitted to PRL on April 18, 1994)Comment: Revtex 11 pages, IASSNS-HEP-94/27 (April 18, 1994

Viral proteins expressed in the protozoan parasite Eimeria tenella are detected by the chicken immune system

BACKGROUND: Eimeria species are parasitic protozoa that cause coccidiosis, an intestinal disease commonly characterised by malabsorption, diarrhoea and haemorrhage that is particularly important in chickens. Vaccination against chicken coccidiosis is effective using wild-type or attenuated live parasite lines. The development of protocols to express foreign proteins in Eimeria species has opened up the possibility of using Eimeria live vaccines to deliver heterologous antigens and function as multivalent vaccine vectors that could protect chickens against a range of pathogens. RESULTS: In this study, genetic complementation was used to express immunoprotective virus antigens in Eimeria tenella. Infectious bursal disease virus (IBDV) causes Gumboro, an immunosuppressive disease that affects productivity and can interfere with the efficacy of poultry vaccination programmes. Infectious laryngotracheitis virus (ILTV) causes a highly transmissible respiratory disease for which strong cellular immunity and antibody responses are required for effective vaccination. Genes encoding the VP2 protein from a very virulent strain of IBDV (vvVP2) and glycoprotein I from ILTV (gI) were cloned downstream of 5’Et-Actin or 5’Et-TIF promoter regions in plasmids that also contained a mCitrine fluorescent reporter cassette under control of the 5’Et-MIC1 promoter. The plasmids were introduced by nucleofection into E. tenella sporozoites, which were then used to infect chickens. Progeny oocysts were sorted by FACS and passaged several times in vivo until the proportion of fluorescent parasites in each transgenic population reached ~20 % and the number of transgene copies per parasite genome decreased to < 10. All populations were found to transcribe and express the transgene and induced the generation of low titre, transgene-specific antibodies when used to immunise chickens. CONCLUSIONS: E. tenella can express antigens of other poultry pathogens that are successfully recognised by the chicken immune system. Nonetheless, further work has to be done in order to improve the levels of expression for its future use as a multivalent vaccine vector. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13071-016-1756-2) contains supplementary material, which is available to authorized users