363 research outputs found

    Children’s emotional experience two years after an earthquake: An exploration of knowledge of earthquakes and associated emotions

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    A major earthquake has a potentially highly traumatic impact on children’s psychological functioning. However, while many studies on children describe negative consequences in terms of mental health and psychiatric disorders, little is known regarding how the developmental processes of emotions can be affected following exposure to disasters. Objectives We explored whether and how the exposure to a natural disaster such as the 2012 Emilia Romagna earthquake affected the development of children’s emotional competence in terms of understanding, regulating, and expressing emotions, after two years, when compared with a control group not exposed to the earthquake. We also examined the role of class level and gender. Method The sample included two groups of children (n = 127) attending primary school: The experimental group (n = 65) experienced the 2012 Emilia Romagna earthquake, while the control group (n = 62) did not. The data collection took place two years after the earthquake, when children were seven or ten-year-olds. Beyond assessing the children’s understanding of emotions and regulating abilities with standardized instruments, we employed semi-structured interviews to explore their knowledge of earthquakes and associated emotions, and a structured task on the intensity of some target emotions. Results We applied Generalized Linear Mixed Models. Exposure to the earthquake did not influence the understanding and regulation of emotions. The understanding of emotions varied according to class level and gender. Knowledge of earthquakes, emotional language, and emotions associated with earthquakes were, respectively, more complex, frequent, and intense for children who had experienced the earthquake, and at increasing ages. Conclusions Our data extend the generalizability of theoretical models on children’s psychological functioning following disasters, such as the dose-response model and the organizational-developmental model for child resilience, and provide further knowledge on children’s emotional resources related to natural disasters, as a basis for planning educational prevention programs

    After Modern Jazz: The Avant-Garde and Jazz Historiography.

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    After Modern Jazz rethinks the history of the jazz avant-garde in dialogue with aesthetic philosophy, critical theory, and African American history. It focuses on the conjuncture of the late 1960s and 1970s as a point from which to revise canonical narratives of jazz history, and connects music and aesthetics to the political economies of cultural production and the transnational politics of decolonization. Part I of the dissertation develops an ideology critique of jazz historiography, posing an explanation for the absence of 1970s experimentalism from jazz history in the unsymbolizable historical break of “1968”, and reframing the emergence and development of “jazz discourse” in the 20th century as a hegemonic struggle in which “jazz” knitted together contradictory ideological and racial projects. A reinterpretation of Theodor Adorno’s notorious attack on jazz suggests its continuing relevance for theorizing the conjunction of critical theory and improvisation. Part II of the dissertation analyzes several key musical and counter-ideological projects of the avant-garde from 1965-1977. The jazz panels of the mid-1960s were a public stage for the performance of a masculinist black-white political dialectic, and musician Archie Shepp’s politics of culture emerged within and against the silences and foreclosures of the historiography of slavery in the U.S. The jazz avant-garde displaced the American popular song as the raw material of jazz improvisation with a new constitutive outside: a variety of compositional languages and an undifferentiated field of “world music.” Amid the contradictory cultural politics of African decolonization and revolutionary movements, the performance of African American musicians at the 1969 Pan-African Festival of Arts and Culture in Algiers offers a perspective on transnational and diasporic cultural formation. Finally, the dissertation interprets the mid-1970s popularity of duo improvisation as an accommodation to the conditions imposed on artistic practice by an emerging regime of neoliberalism. While the improvisatory music made in the 1970s explore the sensory terrain of a politics that can oppose and resist neoliberalism, those resources for resistance are densely encoded within the music’s aesthetic project: the duo, along with other avant-garde musical aesthetics, constitute in Adorno’s terms a “self-unconscious historiography of their epoch.”Ph.D.HistoryUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/89753/1/macleanr_1.pd

    Opportunistic Sampling at a Deep-water Synthetic Drilling Fluid Discharge Site in the Gulf of Mexico

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    Two opportunistic benthic surveys were conducted at an offshore semisubmersible oil drilling rig located in 565 m of water on the continental slope of the Gulf of Mexico to determine the extent of synthetic-based drilling fluid (Petrofree LE) concentrations in surrounding sediments and the composition of the associated macrofauna and megafauna communities. Sediment concentrations of Petrofree LE ranged from 89 to 198,320 μg/g in surficial sediments (0-2 cm) and from 4 to 85,821 mg/g in the 2-5 cm stratum. The highest Petrofree LE concentrations were located 50-75 m northeast of the discharge site, a phenomenon that may have been related to surface and midwater currents in the vicinity of the rig. Although no direct quantitative measures of in situ degradation are available, high concentrations of Petrofree LE relative to discharge periodicity suggest lower than anticipated rates at this deep-water site. Between July 1997 and March 1998, the densities of polychaetes and gastropods increased sharply in the study area. In March, polychaete (primarily dorvilleids) density, gastropod density, and Petrofree concentrations were all significantly higher northeast of the drill site compared with southwest. Polychaete and gastropod densities northeast of the drill site were roughly 3,600 and 3,000 times higher than those reported in eastern and western areas of the northern Gulf of Mexico at similar depths, respectively

    Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline

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    <b>Objective</b>: MicroRNAs (miRNAs) are small noncoding RNAs that have the capacity to control protein production through binding "seed" sequences within a target mRNA. Each miRNA is capable of potentially controlling hundreds of genes. The regulation of miRNAs in the lung during the development of pulmonary arterial hypertension (PAH) is unknown.<p></p> <b>Methods and Results</b>: We screened lung miRNA profiles in a longitudinal and crossover design during the development of PAH caused by chronic hypoxia or monocrotaline in rats. We identified reduced expression of Dicer, involved in miRNA processing, during the onset of PAH after hypoxia. MiR-22, miR-30, and let-7f were downregulated, whereas miR-322 and miR-451 were upregulated significantly during the development of PAH in both models. Differences were observed between monocrotaline and chronic hypoxia. For example, miR-21 and let-7a were significantly reduced only in monocrotaline-treated rats. MiRNAs that were significantly regulated were validated by quantitative polymerase chain reaction. By using in vitro studies, we demonstrated that hypoxia and growth factors implicated in PAH induced similar changes in miRNA expression. Furthermore, we confirmed miR-21 downregulation in human lung tissue and serum from patients with idiopathic PAH.<p></p> <b>Conclusion</b>: Defined miRNAs are regulated during the development of PAH in rats. Therefore, miRNAs may contribute to the pathogenesis of PAH and represent a novel opportunity for therapeutic intervention.<p></p&gt

    Effects of transcutaneous electric acupoint stimulation on drug use and responses to cue-induced craving: a pilot study

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    Background: Transcutaneous electric acupoint stimulation (TEAS) avoids the use of needles, and instead delivers a mild electric current at traditional acupoints. This technique has been used for treating heroin addiction, but has not been systematically tested for other drugs of abuse. This study aims to investigate the effects of TEAS on drug addiction. Methods: Volunteers who were either cocaine-dependent (n = 9) or cannabis-dependent (n = 11) but were not seeking treatment for their dependence participated in a within-subject, single-blind study. Treatment consisted of twice daily 30-minute sessions of TEAS or sham stimulation for 3.5 days. The active TEAS levels were individually adjusted to produce a distinct twitching response in the fingers, while the sham stimulation involved 2 minutes of stimulation at threshold levels followed by 28 minutes of stimulation below the detection levels. The participants recorded their drug use and drug cravings daily. At 1 hour after the last morning session of TEAS or sham stimulation, a cue-induced craving EEG evaluation was conducted. Event-related P300 potentials (ERPs) were recorded, sorted, and analyzed for specific image types (neutral objects, non-drug-related arousing images, or drug-related images). Results: TEAS treatment did not significantly reduce the drug use or drug cravings, or significantly alter the ERP peak voltage or latency to peak response. However, the TEAS treatment did significantly modulate several self-reported measures of mood and anxiety. Conclusion: The results of this pilot study with a limited sample size suggest that the acupoint stimulation techniques and protocol used in this trial alone do not significantly reduce cravings for or use of cocaine or cannabis. The findings that TEAS modulates mood and anxiety suggest that TEAS could be used as an adjunct in a multimodal therapy program to treat cocaine and cannabis dependence if confirmed in a full randomized controlled clinical trial

    Common garden experiments reveal uncommon responses across temperatures, locations, and species of ants

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    Population changes and shifts in geographic range boundaries induced by climate change have been documented for many insect species. On the basis of such studies, ecological forecasting models predict that, in the absence of dispersal and resource barriers, many species will exhibit large shifts in abundance and geographic range in response to warming. However, species are composed of individual populations, which may be subject to different selection pressures and therefore may be differentially responsive to environmental change. Asystematic responses across populations and species to warming will alter ecological communities differently across space. Common garden experiments can provide a more mechanistic understanding of the causes of compositional and spatial variation in responses to warming. Such experiments are useful for determining if geographically separated populations and co-occurring species respond differently to warming, and they provide the opportunity to compare effects of warming on fitness (survivorship and reproduction). We exposed colonies of two common ant species in the eastern United States, Aphaenogaster rudis and Temnothorax curvispinosus, collected along a latitudinal gradient from Massachusetts to North Carolina, to growth chamber treatments that simulated current and projected temperatures in central Massachusetts and central North Carolina within the next century. Regardless of source location, colonies of A. rudis, a keystone seed disperser, experienced high mortality and low brood production in the warmest temperature treatment. Colonies of T. curvispinosus from cooler locations experienced increased mortality in the warmest rearing temperatures, but colonies from the warmest locales did not. Our results suggest that populations of some common species may exhibit uniform declines in response to warming across their geographic ranges, whereas other species will respond differently to warming in different parts of their geographic ranges. Our results suggest that differential responses of populations and species must be incorporated into projections of range shifts in a changing climate.©2012 The Authors. Ecology and Evolution published by Blackwell Publishing Ltd

    Explaining Myanmar's Regime Transition: The Periphery is Central

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    In 2010, Myanmar (Burma) held its first elections after 22 years of direct military rule. Few compelling explanations for this regime transition have emerged. This article critiques popular accounts and potential explanations generated by theories of authoritarian ‘regime breakdown’ and ‘regime maintenance’. It returns instead to the classical literature on military intervention and withdrawal. Military regimes, when not terminated by internal factionalism or external unrest, typically liberalise once they feel they have sufficiently addressed the crises that prompted their seizure of power. This was the case in Myanmar. The military intervened for fear that political unrest and ethnic-minority separatist insurgencies would destroy Myanmar’s always-fragile territorial integrity and sovereignty. Far from suddenly liberalising in 2010, the regime sought to create a ‘disciplined democracy’ to safeguard its preferred social and political order twice before, but was thwarted by societal opposition. Its success in 2010 stemmed from a strategy of coercive state-building and economic incorporation via ‘ceasefire capitalism’, which weakened and co-opted much of the opposition. Having altered the balance of forces in its favour, the regime felt sufficiently confident to impose its preferred settlement. However, the transition neither reflected total ‘victory’ for the military nor secured a genuine or lasting peace

    Proteomic analysis of the Plasmodium male gamete reveals the key role for glycolysis in flagellar motility.

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    BACKGROUND: Gametogenesis and fertilization play crucial roles in malaria transmission. While male gametes are thought to be amongst the simplest eukaryotic cells and are proven targets of transmission blocking immunity, little is known about their molecular organization. For example, the pathway of energy metabolism that power motility, a feature that facilitates gamete encounter and fertilization, is unknown. METHODS: Plasmodium berghei microgametes were purified and analysed by whole-cell proteomic analysis for the first time. Data are available via ProteomeXchange with identifier PXD001163. RESULTS: 615 proteins were recovered, they included all male gamete proteins described thus far. Amongst them were the 11 enzymes of the glycolytic pathway. The hexose transporter was localized to the gamete plasma membrane and it was shown that microgamete motility can be suppressed effectively by inhibitors of this transporter and of the glycolytic pathway. CONCLUSIONS: This study describes the first whole-cell proteomic analysis of the malaria male gamete. It identifies glycolysis as the likely exclusive source of energy for flagellar beat, and provides new insights in original features of Plasmodium flagellar organization
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