929 research outputs found

    From Honors Student to Honors Coordinator

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    As part of the National Collegiate Honors Councilā€™s (2022) collection of essays about the value of honors to its graduates (1967ā€“2019), the author reflects on the personal and professional impacts of the honors experience. Every time I begin a new semester, I often think about how my honors professors began their classes. There was a palpable excitement in their voices as they discussed how we would explore the given subject through a variety of lenses, uncovering nontraditional perspectives and allowing the conversation to flow freely. I remember the conversations continuing among my fellow honors students long after the class ended. The interdisciplinary seminars I took as an honors student continue to inspire my teaching today. The coursework in my honors program pushed me to embrace research and academic writing. My honors professors instilled the practice to always ā€œdig deeper,ā€ going beneath the surface level of any given subject. I took many classes that transported me to other worlds, be they Ancient Greece, 90s hip hop, geopolitical landscapes, or the deep writings of authors like the Woolf sisters, Plath, and Austen. Worlds that can easily be forgotten made my education exciting. Today, I not only strive to lead my students in interdisciplinary explorations and to bring the same sense of adventure in uncovering new knowledge, but I also get to run the day-to-day operations of the honors program at the college where I am now employed

    National Scale-up of Zinc Promotion in Nepal: Results from a Post-project Population-based Survey

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    The World Health Organization and the United Nations Children's Fund recommend using a new oral rehydration solution (ORS) plus zinc supplementation for 10-14 days for the treatment of diarrhoea in children aged less than five years. The Social Marketing Plus for Diarrhoeal Disease Control: Point of Use Water Disinfection and Zinc Treatment (POUZN) project in Nepal was one of the first zinc-promotion projects to move beyond pilot efforts into a scaled-up programme with national-level reach. This study used data from a survey conducted in 26 districts in Nepal in 2008 to examine zinc-use behaviour, knowledge, and beliefs of caregivers of children aged less than six years, other diarrhoea-treatment practices, and recollection of project communication messages. The results of the survey indicated that, by six months following the onset of a zinc-promotion campaign, the majority (67.5%) of children (n=289), aged less than six years, with diarrhoea were treated with ORS, and 15.4% were treated with zinc. Over half (53.1%) of all caregivers (n=3,550) interviewed had heard about zinc products; most (97.1%) of those who had heard of zinc knew that zinc should be used for the treatment of diarrhoea. Zinc-related knowledge and behaviours were positively associated with recall of communication messages. Children whose caregivers recalled the mass-media message that zinc should be used for 10 days [odds ratio (OR)=2.02, 95% confidence interval (CI) 1.85-2.19] and whose caregivers perceived that zinc is easy to obtain (OR=1.76, 95% CI 1.49-2.09) were more likely to be treated with zinc for 10 days, along with ORS. The findings demonstrated that mass media play an important role in increasing caregiversā€™ knowledge about zinc and encouraging trial and correct use. Future efforts should also focus on understanding the factors that motivate providers to continue recommending antibiotics and antidiarrhoeals instead of zinc. These findings are being used for informing the design and implementation of zinc programmes in other developing countries with a high prevalence of diarrhoea

    Cultivating Delight, Crossing Divides, and Solving Impossible Problems: Lessons Learned from a Year of Virtual Conferences

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    This chapter highlights some of the lessons learned from a year of virtual conferences held by three different honors organizations, the Southern Regional Honors Council (SRHC), the Northeast Regional Honors Council (NRHC), and the Kentucky Honors Roundtable (KHR) during the COVID-19 pandemic

    Changing Beliefs about Trauma: A Qualitative Study of Cognitive Processing Therapy

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    Background: Controlled qualitative methods complement quantitative treatment outcome research and enable a more thorough understanding of the effects of therapy and the suspected mechanisms of action. Aims: Thematic analyses were used to examine outcomes of cognitive processing therapy (CPT) for posttraumatic stress disorder (PTSD) in a randomized controlled trial of individuals diagnosed with military-related PTSD ( n = 15). Method: After sessions 1 and 11, participants wrote ā€œimpact statementsā€ describing their appraisals of their trauma and beliefs potentially impacted by traumatic events. Trained raters coded each of these statements using a thematic coding scheme. Results: An analysis of thematic coding revealed positive changes over the course of therapy in participantsā€™ perspective on their trauma and their future, supporting the purported mechanisms of CPT. Conclusion: Implications of this research for theory and clinical practice are discussed

    Impact of Feeding Syngenta EnogenĀ® Feed Corn Compared to Control Corn in Different Diet Scenarios to Finishing Beef Cattle

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    The objective of this pooled statistical analysis was to evaluate Syngenta EnogenĀ® Feed Corn (EFC) versus conventional corn (CON) when fed as either dry-rolled corn (DRC) or highmoisture corn (HMC) for effects on finishing beef cattle performance and carcass characteristics. Corns were evaluated in diets with byproduct inclusion rates of 0, 15, 18, 20, and 30% distiller grains or 25 and 35% Sweet BranĀ® (a commercial corn gluten feed product). Seven trials (n = 1856) consisting of 200 pen means comparing 26 diet treatments were analyzed using regression in a pooled analysis. When EFC was processed as DRC, the gain efficiency (G:F) improved compared with CON, but the response to feeding EFC decreased from a 4.8% improvement to no improvement compared to CON as distiller grains increased from 0 to 30%, but was significantly improved due to feeding EFC in diets with 0 to 18% distiller grains. Feeding cattle EFC as DRC increased the average daily gain (ADG) and G:F by 4.5% compared with CON corn in diets containing Sweet BranĀ®. No improvements in animal performance were observed when cattle were fed EFC compared to CON when processed as HMC in any situation. Feeding EnogenĀ® corn improved the gain efficiency of finishing cattle compared with conventional corn when processed as dry-rolled corn and fed in diets with less than 20% distillers or diets that include Sweet BranĀ®

    National Scale-up of Zinc Promotion in Nepal: Results from a Post-project Population-based Survey

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    The World Health Organization and the United Nations Children\u2019s Fund recommend using a new oral rehydration solution (ORS) plus zinc supplementation for 10-14 days for the treatment of diarrhoea in children aged less than five years. The Social Marketing Plus for Diarrhoeal Disease Control: Point of Use Water Disinfection and Zinc Treatment (POUZN) project in Nepal was one of the first zinc-promotion projects to move beyond pilot efforts into a scaled-up programme with national-level reach. This study used data from a survey conducted in 26 districts in Nepal in 2008 to examine zinc-use behaviour, knowledge, and beliefs of caregivers of children aged less than six years, other diarrhoea-treatment practices, and recollection of project communication messages. The results of the survey indicated that, by six months following the onset of a zinc-promotion campaign, the majority (67.5%) of children (n=289), aged less than six years, with diarrhoea were treated with ORS, and 15.4% were treated with zinc. Over half (53.1%) of all caregivers (n=3,550) interviewed had heard about zinc products; most (97.1%) of those who had heard of zinc knew that zinc should be used for the treatment of diarrhoea. Zinc-related knowledge and behaviours were positively associated with recall of communication messages. Children whose caregivers recalled the mass-media message that zinc should be used for 10 days [odds ratio (OR)=2.02, 95% confidence interval (CI) 1.85-2.19] and whose caregivers perceived that zinc is easy to obtain (OR=1.76, 95% CI 1.49-2.09) were more likely to be treated with zinc for 10 days, along with ORS. The findings demonstrated that mass media play an important role in increasing caregivers\u2019 knowledge about zinc and encouraging trial and correct use. Future efforts should also focus on understanding the factors that motivate providers to continue recommending antibiotics and antidiarrhoeals instead of zinc. These findings are being used for informing the design and implementation of zinc programmes in other developing countries with a high prevalence of diarrhoea

    Temperatureā€“time evolution of the Assynt Terrane of the Lewisian Gneiss Complex of Northwest Scotland from zircon U-Pb dating and Ti thermometry

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    The Lewisian Gneiss Complex of Northwest Scotland is a classic Precambrian basement gneiss complex. The Lewisian is divided into a number of terranes on the basis of structural, metamorphic and geochronological evidence. The most well-studied of these is the Assynt Terrane, which forms the central part of the Lewisian outcrop on the Scottish mainland. Field evidence shows that it has a complex tectonothermal history, the early stages of which remain poorly constrained. This paper sets out to better understand the chronology and thermal evolution of the Assynt Terrane through zircon U-Pb dating and Ti-in-zircon thermometry, the latter applied to the Lewisian for the first time. This is placed in context by integration with detailed field mapping, sample petrography, zircon cathodoluminescence (CL) imaging and rare earth element (REE) analysis. Zircons from six tonalite-trondhjemite-granodiorite (TTG) gneiss samples and two metasedimentary gneiss samples were analysed. The TTG gneisses were predominantly retrogressed to amphibolite-facies; zircons showed a range of CL zoning patterns and REE profiles were similar to those expected for magmatic zircon grains. Zircons from the metasedimentary gneisses also displayed a range of CL zoning patterns and are depleted relative to chondrite in heavy REEs due to the presence of garnet. Zircon analysis records a spread of concordant U-Pb ages from āˆ¼2500 to 3000 Ma. There is no evident correlation of ages with location in the crystal or with CL zoning pattern. A weighted average of 207Pb/206Pb ages from the oldest igneous zircon cores from the TTG gneiss samples gives an age of 2958 Ā± 7 Ma, interpreted to be a magmatic protolith crystallisation age. A weighted average of 207Pb/206Pb ages of the youngest metamorphic rims yields an age of 2482 Ā± 6 Ma, interpreted to represent the last high-grade metamorphism to affect these rocks. Ti-in-zircon thermometry records minimum temperatures of 710ā€“834 Ā°C, interpreted to reflect magmatic crystallisation. REE profiling enabled the zircons in the metasedimentary rocks to be linked to the presence of metamorphic garnet, but resetting of U-Pb systematics precluded the determination of either protolith or metamorphic ages. Zircons from the metasedimentary gneisses generally record higher minimum temperatures (803ā€“847 Ā°C) than the TTG gneisses, interpreted to record zircon crystallisation in an unknown protolith

    Re-evaluating ambiguous age relationships in Archean cratons: Implications for the origin of ultramafic-mafic complexes in the Lewisian Gneiss Complex

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    Archean ultramafic-mafic complexes have been the focus of important and often contentious geological and geodynamic interpretations. However, their age relative to the other components of Archean cratons are often poorly-constrained, introducing significant ambiguity when interpreting their origin and geodynamic significance. The Lewisian Gneiss Complex (LGC) of the northwest Scottish mainland ā€“ a high-grade, tonalite-trondhjemite-granodiorite (TTG) terrane that forms part of the North Atlantic Craton (NAC) ā€“ contains a number of ultramafic-mafic complexes whose origin and geodynamic significance have remained enigmatic since they were first described. Previous studies have interpreted these complexes as representing a wide-range of geological environments, from oceanic crust, to the sagducted remnants of Archean greenstone belts. These interpretations, which are often critically dependent upon the ages of the complexes relative to the surrounding rocks, have disparate implications for Archean geodynamic regimes (in the NAC and globally). Most previous authors have inferred that the ultramafic-mafic complexes of the LGC pre-date the TTG magmas. This fundamental age relationship is re-evaluated in this investigation through re-mapping of the Geodhā€™ nan Sgadan Complex (where tonalitic gneiss reportedly cross-cuts mafic rocks) and new mapping of the 7ā€Ækm2 Ben Strome Complex (the largest ultramafic-mafic complex in the LGC), alongside detailed petrography and spinel mineral chemistry. This new study reveals that, despite their close proximity in the LGC (12ā€Ækm), the Ben Strome and Geodhā€™ nan Sgadan Complexes are petrogenetically unrelated, indicating that the LGC (and thus NAC) records multiple temporally and/or petrogenetically distinct phases of ultramafic-mafic Archean magmatism that has been masked by subsequent high-grade metamorphism. Moreover, field observations and spinel mineral chemistry demonstrate that the Ben Strome Complex represents a layered intrusion that was emplaced into a TTG-dominated crust. Further to representing a significant re-evaluation of the LGCā€™s magmatic evolution, these findings have important implications for the methodologies utilised in deciphering the origin of Archean ultramafic-mafic complexes globally, where material suitable for dating is often unavailable and field relationships are commonly ambiguous

    The NIH-NIAID Filariasis Research Reagent Resource Center

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    Filarial worms cause a variety of tropical diseases in humans; however, they are difficult to study because they have complex life cycles that require arthropod intermediate hosts and mammalian definitive hosts. Research efforts in industrialized countries are further complicated by the fact that some filarial nematodes that cause disease in humans are restricted in host specificity to humans alone. This potentially makes the commitment to research difficult, expensive, and restrictive. Over 40 years ago, the United States National Institutes of Healthā€“National Institute of Allergy and Infectious Diseases (NIH-NIAID) established a resource from which investigators could obtain various filarial parasite species and life cycle stages without having to expend the effort and funds necessary to maintain the entire life cycles in their own laboratories. This centralized resource (The Filariasis Research Reagent Resource Center, or FR3) translated into cost savings to both NIH-NIAID and to principal investigators by freeing up personnel costs on grants and allowing investigators to divert more funds to targeted research goals. Many investigators, especially those new to the field of tropical medicine, are unaware of the scope of materials and support provided by the FR3. This review is intended to provide a short history of the contract, brief descriptions of the fiilarial species and molecular resources provided, and an estimate of the impact the resource has had on the research community, and describes some new additions and potential benefits the resource center might have for the ever-changing research interests of investigators

    Identifying and prioritising unanswered research questions for people with hyperacusis: James Lind Alliance Hyperacusis Priority Setting Partnership

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    Objective To determine research priorities in hyperacusis that key stakeholders agree are the most important. Design/setting A priority setting partnership using two international surveys, and a UK prioritisation workshop, adhering to the six-staged methodology outlined by the James Lind Alliance. Participants People with lived experience of hyperacusis, parents/carers, family and friends, educational professionals and healthcare professionals who support and/or treat adults and children who experience hyperacusis, including but not limited to surgeons, audiologists, psychologists and hearing therapists. Methods The priority setting partnership was conducted from August 2017 to July 2018. An international identification survey asked respondents to submit any questions/uncertainties about hyperacusis. Uncertainties were categorised, refined and rephrased into representative indicative questions using thematic analysis techniques. These questions were verified as ā€˜unansweredā€™ through searches of current evidence. A second international survey asked respondents to vote for their top 10 priority questions. A shortlist of questions that represented votes from all stakeholder groups was prioritised into a top 10 at the final prioritisation workshop (UK). Results In the identification survey, 312 respondents submitted 2730 uncertainties. Of those uncertainties, 593 were removed as out of scope, and the remaining were refined into 85 indicative questions. None of the indicative questions had already been answered in research. The second survey collected votes from 327 respondents, which resulted in a shortlist of 28 representative questions for the final workshop. Consensus was reached on the top 10 priorities for future research, including identifying causes and underlying mechanisms, effective management and training for healthcare professionals. Conclusions These priorities were identified and shaped by people with lived experience, parents/carers and healthcare professionals, and as such are an essential resource for directing future research in hyperacusis. Researchers and funders should focus on addressing these priorities.Additional co-authors: Tracey Pollard, Helen Henshaw, Toto A Gronlund, Derek J Hoar
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