198 research outputs found

    Actors’ Interpretations and Organisational Change Processes: The Case of the University of Ghana’s Strategic Vision of Becoming a ’World Class University’

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    Despite its seemingly subjective and ambiguous nature, the notion of a World Class University (WCU) appears both established and widely discussed in higher education discourses over the last decade. At the same time, some scholars have argued that the notion does not fit or refer to universities in Africa. In the year 2010, the University of Ghana which is the largest university in the country, agreed upon a strategic vision for the university emphasizing the notion of WCU. In this regard the question emerges, what this WCU vision at the University of Ghana actually means in practice, since it is not prescribed by the university’s leadership but left open for interpretation, operationalization and further implementation by all members of the organization. Using an interdependency management perspective, this paper examines how university leadership and academic staff interpret the WCU strategic vision at the University of Ghana and to what extent organizational change processes are the result of the implementation of the university’s WCU strategy. Keywords: World Class University, management, academics, interdependency managemen

    Internationalization of higher education institutions in Northern Europe in the light of Bologna - National and Institutional Case Studies

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    This study is the basis for a summary report concerning the internationalization of higher education in the Nordic countries (see NIFU STEP report 8/2004)

    Issues in higher education policy : an update on higher education policy issues in 2004 in 11 Western countries

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    Higher education is a dynamic field. It is, however, also a field where changes donÂżt take place overnight. This 2004 update report covers a period of 1.5 years, a period in which some earlier policy initiatives have been implemented and new ones have emerged. It is therefore not surprising to observe that many of the policy issues on the agenda in the previous Update Report (April, 2003) still are a topic of debate today.\ud The main part of the report are the descriptions of the current (2004) higher education debates and policy initiatives for each of the eleven IHEM countries, arranged in four themes educational and research infrastructure, finance, governance and quality. In conclusion, four `overarchingÂż policy issues in contemporary European (and Australian) higher education are discussed. These issues are:\ud * The Bologna process and changing degree structures\ud * The changing organisation of research\ud * Financial accountability and responsibility\ud * Interactive governanc

    Four-qubit device with mixed couplings

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    We present the first experimental results on a device with more than two superconducting qubits. The circuit consists of four three-junction flux qubits, with simultaneous ferro- and antiferromagnetic coupling implemented using shared Josephson junctions. Its response, which is dominated by the ground state, is characterized using low-frequency impedance measurement with a superconducting tank circuit coupled to the qubits. The results are found to be in excellent agreement with the quantum-mechanical predictions.Comment: REVTeX 4, 5pp., 7 EPS figure files. N.B.: "Alec" is my first, and "Maassen van den Brink" my family name. v2: final published version, with changed title, different sample micrograph, and several clarification

    Investigations with GMC2021 in experimental models predictive of antimigraine activity and coronary side-effect potential

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    Abstract Several acutely acting antimigraine drugs, including sumatriptan and other second generation 5-HT1D receptor agonists, have the ability to constrict porcine carotid arteriovenous anastomoses as well as the human isolated coronary artery. These two experimental models seem to serve as indicators, respectively, for the therapeutic and coronary side-effect potential of the compounds. Using these two models, we have now investigated the effects of GMC2021 (3-[2-(dimethylanimo)ethyl]-5-[(trifluoromethyl)sulfonyl]oxy][1 H]indole oxalate, a close analogue of sumatriptan. GMC2021 (30, 100, 300 and 1000 ÎŒg · kg−1, i.v.) decreased the total carotid blood flow by exclusively decreasing arteriovenous anastomotic blood flow; capillary blood flow to the skin and ears was moderately increased. The mean ± S.E.M. dose of GMC2021 eliciting a 50% decrease (ED50) in the porcine carotid arteriovenous anastomotic blood flow was found to be 1.1 ± 0.3 ÎŒmol · kg−1 and the highest dose (1000 ÎŒg · kg−1) produced a 67 ± 4% reduction. The carotid haemodynamic effects of GMC2021 were reduced by the selective 5-HT1D receptor antagonist, GR127935 (N-[methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2â€Č-methyl-4â€Č-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1-biphenyl]-4-carbboxamide hydrochloride), which completely antagonizes porcine carotid haemodynamic responses to sumatriptan (ED50: 0.16 ÎŒmol · kg−1, i.v.). Compared to sumatriptan (pD2: 6.12 ± 0.15; Emax: 31.3 ± 12.3% of contractions to 100 mM K+), GMC2021 was less potent in constricting the human isolated coronary artery (pD2: 5.45 ± 0.2; Emax: 21.0 ± 4.8% of contractions to 100 mM K+). The above results suggest that GMC2021 constricts carotid arteriovenous anastomoses partly by a 5-HT1D receptor and partly by another, probably novel, receptor and that GMC2021 should be able to abort migraine headaches in patients, with perhaps a less propensity for coronary side effects
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