88,014 research outputs found

    A Note on Pretzelosity TMD Parton Distribution

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    We show that the transverse-momentum-dependent parton distribution, called as Pretzelosity function, is zero at any order in perturbation theory of QCD for a single massless quark state. This implies that Pretzelosity function is not factorized with the collinear transversity parton distribution at twist-2, when the struck quark has a large transverse momentum. Pretzelosity function is in fact related to collinear parton distributions defined with twist-4 operators. In reality, Pretzelosity function of a hadron as a bound state of quarks and gluons is not zero. Through an explicit calculation of Pretzelosity function of a quark combined with a gluon nonzero result is found.Comment: improved explanation, published version in Phys. Lett.

    Finite dimensional integrable Hamiltonian systems associated with DSI equation by Bargmann constraints

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    The Davey-Stewartson I equation is a typical integrable equation in 2+1 dimensions. Its Lax system being essentially in 1+1 dimensional form has been found through nonlinearization from 2+1 dimensions to 1+1 dimensions. In the present paper, this essentially 1+1 dimensional Lax system is further nonlinearized into 1+0 dimensional Hamiltonian systems by taking the Bargmann constraints. It is shown that the resulting 1+0 dimensional Hamiltonian systems are completely integrable in Liouville sense by finding a full set of integrals of motion and proving their functional independence.Comment: 10 pages, in LaTeX, to be published in J. Phys. Soc. Jpn. 70 (2001

    A Coupled AKNS-Kaup-Newell Soliton Hierarchy

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    A coupled AKNS-Kaup-Newell hierarchy of systems of soliton equations is proposed in terms of hereditary symmetry operators resulted from Hamiltonian pairs. Zero curvature representations and tri-Hamiltonian structures are established for all coupled AKNS-Kaup-Newell systems in the hierarchy. Therefore all systems have infinitely many commuting symmetries and conservation laws. Two reductions of the systems lead to the AKNS hierarchy and the Kaup-Newell hierarchy, and thus those two soliton hierarchies also possess tri-Hamiltonian structures.Comment: 15 pages, late

    Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway.

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    BACKGROUND: Tick-borne encephalitis virus (TBEV) is one of the most important flaviviruses that targets the central nervous system (CNS) and causes encephalitides in humans. Although neuroinflammatory mechanisms may contribute to brain tissue destruction, the induction pathways and potential roles of specific chemokines in TBEV-mediated neurological disease are poorly understood. METHODS: BALB/c mice were intracerebrally injected with TBEV, followed by evaluation of chemokine and cytokine profiles using protein array analysis. The virus-infected mice were treated with the CC chemokine antagonist Met-RANTES or anti-RANTES mAb to determine the role of RANTES in affecting TBEV-induced neurological disease. The underlying signaling mechanisms were delineated using RANTES promoter luciferase reporter assay, siRNA-mediated knockdown, and pharmacological inhibitors in human brain-derived cell culture models. RESULTS: In a mouse model, pathological features including marked inflammatory cell infiltrates were observed in brain sections, which correlated with a robust up-regulation of RANTES within the brain but not in peripheral tissues and sera. Antagonizing RANTES within CNS extended the survival of mice and reduced accumulation of infiltrating cells in the brain after TBEV infection. Through in vitro studies, we show that virus infection up-regulated RANTES production at both mRNA and protein levels in human brain-derived cell lines and primary progenitor-derived astrocytes. Furthermore, IRF-3 pathway appeared to be essential for TBEV-induced RANTES production. Site mutation of an IRF-3-binding motif abrogated the RANTES promoter activity in virus-infected brain cells. Moreover, IRF-3 was activated upon TBEV infection as evidenced by phosphorylation of TBK1 and IRF-3, while blockade of IRF-3 activation drastically reduced virus-induced RANTES expression. CONCLUSIONS: Our findings together provide insights into the molecular mechanism underlying RANTES production induced by TBEV, highlighting its potential importance in the process of neuroinflammatory responses to TBEV infection

    Finite difference approximations for a size-structured population model with distributed states in the recruitment

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    In this paper we consider a size-structured population model where individuals may be recruited into the population at different sizes. First and second order finite difference schemes are developed to approximate the solution of the mathematical model. The convergence of the approximations to a unique weak solution with bounded total variation is proved. We then show that as the distribution of the new recruits become concentrated at the smallest size, the weak solution of the distributed states-at-birth model converges to the weak solution of the classical Gurtin-McCamy-type size-structured model in the weak∗^* topology. Numerical simulations are provided to demonstrate the achievement of the desired accuracy of the two methods for smooth solutions as well as the superior performance of the second-order method in resolving solution-discontinuities. Finally we provide an example where supercritical Hopf-bifurcation occurs in the limiting single state-at-birth model and we apply the second-order numerical scheme to show that such bifurcation occurs in the distributed model as well

    Assessment of hearing status in children with non-syndromic cleft lip and/or palate in China

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    Poster SessionConference Theme: Making Hearing Health a Global PriorityNon-syndromic cleft lip and/or palate (NSCL/P) is a common congenital craniofacial malformation worldwide, and there are a large number of babies born with CL/P every year in China. Children with NSCL/P often have a high prevalence of middle ear disorder because of Eustachian tube dysfunction. However, the degree of possible conductive hearing loss and distribution of affected frequencies of pure tone test thresholds in school age children with NSCL/P have been rarely reported in China or other developing countries. In addition to peripheral hearing loss, children with NSCL/P may have a higher than typical prevalence of (central) auditory processing disorder [(C)APD] reflected in their poor academic performance and delayed speech or language development. This study aimed to use a medical history ...postprin
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