Analisis Finansial Budidaya Ikan dalam Karamba Jaring Apung di Sungai Melawi Kecamatan Pinoh Utara Kabupaten Melawi

Aquaculture in Floating Net Cage (FNC) is one of the reliable aquaculture technologies that is used to optimize the utilization of waters on rivers, lakes and reservoirs. The types of fish that is usually preserved in Floating Net Cage are Gold Fish (Cyprinus carpio) and Nile Tilapia (Oreochromis niloticus). Survey method is applied in this research and data sample is drawn from the farmer population of floating net cages in Kecamatan Pinoh Utara. The objective of this study is to determine the financial feasibility of aquaculture with Floating Net Cage (FNC) system. This achieved by considering Net Present Value (NPV), IRR (Internal Rate of Return), Net Benefit-Cost Ratio (B/C Ratio), Analysis of PP (Payback Periods) and Sensitivity Analysis. The result indicates that aquaculture of Nile Tilapia and Gold-Fish with Floating Net Cage (FNC) system was financially significant shown by Net Presents Value (NPV) 227.246.769,84 rupiahs, Internal Rate of Return (IRR) 190,97%, Net Benefit Cost ratio (B/C Ratio) 4,34 and Payback Periods (PP) 0,53 years (6 months 10 days). The sensitivity analysis indicates that if there was an increase in operational costs, the amount should not be more than 304,19% and if there was a decrease in profits, the amount should not be more than 44,11%. Keywords: Financial Analysis, Aquaculture, Floating Net Cage, Net Present Value (NPV), Internal Rate of Return (IRR), Net Benefit-Cost Ratio (B/C Ratio)

Attenuation of cisplatin-induced nephrotoxicity in rats using zerumbone

Zerumbone is a natural compound isolated from the fresh rhizomes of Zingiber zerumbet. This bioactive compound has shown a chemo-preventive, anti-inflammatory and free radical scavenging activities. This study examines the effect of zerumbone on the extent of tissue damage in cisplatininduced nephrotoxicity in rats. The rats received a single dose injection of 10 mg/kg cisplatin. Other groups of rats received zerumbone (100 and 200 mg/kg), corn oil or the vehicle, dimethyl sulfoxide (DMSO) intraperitoneally for 4 days prior to cisplatin-injections. All animals were decapitated 16 h after cisplatin injection. Trunk blood was collected and analyzed for blood urea nitrogen (BUN) and serum creatinine. Kidney tissue was kept for the quantification of malondialdehyde and glutathione levels. Histopathological investigations were carried out and the severity of lesions was scored to obtain quantitative data. Our study revealed that zerumbone reduced kidney damage and preserved renal functions as proved by microscopic observations and lesion scoring. The increased in kidney malondialdehyde (MDA) levels with simultaneous glutathione (GSH) reduction in cisplatin treated group was attenuated by zerumbone (p < 0.05). It was concluded that zerumbone is beneficial in cisplatininducedrenal dysfunction and organ damage in rats possibly via the prevention of lipid per oxidation and preservation of antioxidant glutathione

Phytochemical composition and toxicity of the aqueous extract of Parkia biglobosa pods in adult Clarias gariepinus

The phytochemical composition and toxicological evaluation of the aqueous extract of Parkia biglobosa pods in adult Clarias gariepinus was investigated over a 96-h exposure period. The aqueous extract of the pods was freeze-dried and screened for its phytochemical constituents. This revealed the presence of glycosides, alkaloids, saponins, steroids and triterpenes, tannins, carbohydrates and flavonoids but no anthraquinones and fixed oils. The fish were exposed to varying concentrations of the extract in a static acute toxicity bioassay. The exposed fish showed initial signs of agitated and erratic movements followed by signs of respiratory distress and abnormal nervous compromise, including mortality in some of the exposed fish. No such obvious signs of toxicity were recorded in the unexposed control fish. The appearance and intensity of the signs were both concentrations and exposure period-dependent. Mean mortality was significantly (p<0.05) related to extract concentrations and exposure period. The median lethal concentration of the extract in exposed fish over the 96-h exposure period was calculated to be 115.38 mg/l. Parkia biglobosa pods contained some toxicologically active constituents that can be meaningfully exploited to harvest fish from water bodies. However, this should be done with great care as the abusive use (higher concentrations) of this extract could result in extract residues in the exposed fish that might pose a risk to the consumers of such fish.Keywords: Clarias gariepinus, Parkia biglobosa pods, phytochemical constituents, toxicity

Toxicological Evaluation of Ethanol Extract of Adenium obesum Stem Bark in African Catfish, Clarias gariepinus

The toxicity of ethanol extract of Adenium obesum stem bark as a tool foraquaculture pond management prior to the stocking of desired fish species was evaluated in Clarias gariepinus over a 96-h exposure. The fish were exposed to 6.25 mgL-1, 7.50 mgL-1, 8.20 mgL-1, 8.80 mgL-1 and 10.00 mgL-1 of the extract and a control in an acute static toxicity bioassay after performing a range finding test to determine the median lethal concentration (LC50) of the extract. Exposed fish showed signs of changed behaviours with adaptive responses, respiratory distress and nervous compromise, including mortality in some of the exposed fish. The appearance and intensities of the observed signs were concentration and exposure period-dependent. An LC50 value of 7.35 mgL-1 was establishedfor the extract in the exposed fish where mean mortality was significantly (p<0.05) concentration and exposure period-dependent. The toxic nature of the extract in the exposed hardy fish can be exploited for effective aquaculture pond management against some unwanted predatory and weed aquatic organisms. However, the indiscriminate use of higher extract concentrations could seriously jeopardise the biodiversity of any aquaticenvironment

ANALISIS FINANSIAL BUDIDAYA IKAN DALAM KARAMBA JARING APUNG DI SUNGAI MELAWI KECAMATAN PINOH UTARA KABUPATEN MELAWI

Aquaculture in Floating Net Cage (FNC) is one of the reliable aquaculture technologies that is used to optimize the utilization of waters on rivers, lakes and reservoirs. The types of fish that is usually preserved in Floating Net Cage are Gold Fish (Cyprinus carpio) and Nile Tilapia (Oreochromis niloticus). Survey method is applied in this research and data sample is drawn from the farmer population of floating net cages in Kecamatan Pinoh Utara. The objective of this study is to determine the financial feasibility of aquaculture with Floating Net Cage (FNC) system. This achieved by considering Net Present Value (NPV), IRR (Internal Rate of Return), Net Benefit-Cost Ratio (B/C Ratio), Analysis of PP (Payback Periods) and Sensitivity Analysis. The result indicates that aquaculture of Nile Tilapia and Gold-Fish with Floating Net Cage (FNC) system was financially significant shown by Net Presents Value (NPV) 227.246.769,84 rupiahs, Internal Rate of Return (IRR) 190,97%, Net Benefit Cost ratio (B/C Ratio) 4,34 and Payback Periods (PP) 0,53 years (6 months 10 days). The sensitivity analysis indicates that if there was an increase in operational costs, the amount should not be more than 304,19% and if there was a decrease in profits, the amount should not be more than 44,11%.   Keywords: Financial Analysis, Aquaculture, Floating Net Cage, Net Present Value (NPV), Internal Rate of Return (IRR), Net Benefit-Cost Ratio (B/C Ratio)

GC/MS determination of bioactive components and antibacterial properties of Goniothalamus umbrosusextracts

In this study, the antibacterial activity and chemical composition of Goniothalamus umbrosus leaves extracts were evaluated. The antibacterial activity was investigated using two gram-positive bacteria, Methicillin resistant Staphylococcus aureus (MRSA) and Bacillus subtilis B29, and two gram-negative bacteria, Pseudomonas aeruginosa 60690 and Salmonella choleraesuis. The activity was tested using disc diffusion and minimum inhibitory concentration assays. The chemical compositions of the ethyl acetate extract of G. umbrosus were investigated using Shimadzu gas chromatography–mass spectrometry (GC-17A) while the mass spectra of the compounds found in the extract was matched with the library. The results showed that the  extracts demonstrated broad spectrum antibacterial effects against all tested bacteria. GC/MS analysis of ethyl acetate extract of G. umbrosus revealed the existence of 1-butyl-2-cyclohexen-1-ol (46.84%), benzaldehyde (4.42%) and globulol (4.07%). The results of this study offer a platform of using G. umbrosus as herbal alternative for the current synthetic antimicrobial agents

Monitoring Psychometric States of Recovery to Improve Performance in Soccer Players: A Brief Review

In order to maximize adaptations and to avoid nonfunctional overreaching syndrome or noncontact injury, coaches in high-performance sports must regularly monitor recovery before and after competitions/important training sessions and maintain well-being status. Therefore, quantifying and evaluating psychometric states of recovery during the season in sports teams such as soccer is important. Over the last years, there has been substantial growth in research related to psychometric states of recovery in soccer. The increase in research on this topic is coincident with the increase in popularity obtained by subjective monitoring of the pre-fatigue state of the players before each training sessions or match with a strong emphasis on the effects of well-being or recovery state. Among the subjective methods for players’ control, the Hooper index (HI) assesses the quality of sleep during the previous night, overall stress, fatigue, and delayed-onset muscle soreness. Additionally, the total quality of recovery (TQR) scale measures recovery status. The HI and TQR recorded before each training session or match were affected by the variability of training load (TL) and influenced the physical and technical performances, and the affective aspects of soccer players. Researchers have recommended wellness monitoring soccer players’ psychometric state of recovery before each training session or match in order to detect early signs of fatigue and optimize high-level training performance. This method allows for better detecting signs of individual fatigue and allows coaches to adapt and readjust the TL, and avoid physical and technical gaps in order to improve the performance of soccer players

Histopathological and Biochemical evaluations of the antidotal efficacy of Nigella sativa oil on organophosphate induced hepato-toxicity

Objective: The study was designed to investigate the effects of continuous exposure of dichlorvos (DDVP) on hepatic function and hepatic histomorphology, with the possible antidotal efficacy of Nigella sativa oil (NSO).Methods: Twenty four Wistar rats were randomly divided into four groups, with each group comprising of six rats. The groups were labelled as Sunflower oil (SFO), DDVP, DDVP+NSO and NSO. After 14 days of treatments, blood samples were collected, centrifuged and levels of ALP (Alkaline phosphatase), ALT (Alanine aminotransferase), AST (Aspartate aminotransferase) and GGT (γ-glutamyl-transferase) concentrations were estimated in the serum. The livers were removed and prepared for histopathological examinations and evaluation.Results: The findings of the study shows significant increase in the serum concentration of ALT, ALP, AST and GGT with a marked distortion in the hepatic architecture in rats administered with DDVP. However, Nigella sativa oil (NSO) was observed to ameliorate the levels of impairment in the assessed hepatic function parameters and relatively restoration in the hepatic architecture in DDVP+NSO treated animals when compared to the control and group administered with DDVPonly.Conclusion: The study concludes that impaired liver functions and histomorphological tissue distortions observed in the experimental rats following DDVP exposure were ameliorated following theadministration of NSO.Keywords: Nigella sativa, dichlorvos, antidotal effect, hepatotoxicity, liver function tes

Role of MBL2 polymorphisms in sepsis and survival: A pilot study and in silico analysis

Sepsis is a serious infection-induced syndrome with serious ramifications, especially in intensive care units. Global concern motivated the investigation of the role of related genes’ polymorphism in predicting the liability to infection, sepsis, septic shock and survival. Among these genes is the gene encoding mannose-binding lectin (MBL), with its remarkable importance in the immune system. However, the previous studies showed conflicting results and ambiguity that urged us to engage with this issue in the Egyptian population. Prediction of functional and structural impacts of single nucleotide polymorphisms (SNPs) was done using in silico methods. A prospective observational study was conducted in intensive care units; one hundred and thirty patients were followed up. Genotyping was performed using real-time polymerase chain reaction (RT-PCR) technology. MBL SNPs showed a remarkable high frequency in our population, as well. No significant association was found between MBL2 genotypes and any of our analyses (sepsis, septic shock and survival). Only septic shock and age were independently associated with time of survival by Cox regression analysis. Our study may confirm the redundancy of MBL and the absence of significant impact on sepsis liability and mortality in adult patients

Detection of putative new mutacins by bioinformatic analysis using available web tools

In order to characterise new bacteriocins produced by Streptococcus mutans we perform a complete bioinformatic analyses by scanning the genome sequence of strains UA159 and NN2025. By searching in the adjacent genomic context of the two-component signal transduction system we predicted the existence of many putative new bacteriocins' maturation pathways and some of them were only exclusive to a group of Streptococcus. Computational genomic and proteomic analysis combined to predictive functionnal analysis represent an alternative way for rapid identification of new putative bacteriocins as well as new potential antimicrobial drugs compared to the more traditional methods of drugs discovery using antagonism tests