14 research outputs found

    European analytical calculations compared with a full-scale Brazilian piled embankment

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    Measurements have been carried out in a full-scale Brazilian basal reinforced piled embankment. The subsoil beneath the geosynthetic reinforcement (GR) had been excavated before the installation of the reinforced embankment. The embankment was relatively thin in comparison to the pile cap spacing, resulting in relative much load on the GR. GR strains and settlements have been measured making it possible to validate analytical models. Many analytical design models for the design of piled embankments distinguish two calculation steps; calculation step 1; the arching and calculation step 2 ; the load deflection behaviour of the GR. This papser presents the comparison of the full-scale test with a new step 1 - model ; the Concentric arches model (Van Eekelen et al. 2013) and several step 2 models. The new concentric arches model is an extension on the models of Hewlet and Randolph (1988) and Zaeske (2001) and takes into account the 3D nature of the arching. The new model was developed because experiments had showed a load distribution on the GR in a piled embankment that could not be explained with the existing models. The new model does explain the measured load distribution

    Increasing frailty is associated with higher prevalence and reduced recognition of delirium in older hospitalised inpatients: results of a multi-centre study

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    Purpose Delirium is a neuropsychiatric disorder delineated by an acute change in cognition, attention, and consciousness. It is common, particularly in older adults, but poorly recognised. Frailty is the accumulation of deficits conferring an increased risk of adverse outcomes. We set out to determine how severity of frailty, as measured using the CFS, affected delirium rates, and recognition in hospitalised older people in the United Kingdom. Methods Adults over 65 years were included in an observational multi-centre audit across UK hospitals, two prospective rounds, and one retrospective note review. Clinical Frailty Scale (CFS), delirium status, and 30-day outcomes were recorded. Results The overall prevalence of delirium was 16.3% (483). Patients with delirium were more frail than patients without delirium (median CFS 6 vs 4). The risk of delirium was greater with increasing frailty [OR 2.9 (1.8–4.6) in CFS 4 vs 1–3; OR 12.4 (6.2–24.5) in CFS 8 vs 1–3]. Higher CFS was associated with reduced recognition of delirium (OR of 0.7 (0.3–1.9) in CFS 4 compared to 0.2 (0.1–0.7) in CFS 8). These risks were both independent of age and dementia. Conclusion We have demonstrated an incremental increase in risk of delirium with increasing frailty. This has important clinical implications, suggesting that frailty may provide a more nuanced measure of vulnerability to delirium and poor outcomes. However, the most frail patients are least likely to have their delirium diagnosed and there is a significant lack of research into the underlying pathophysiology of both of these common geriatric syndromes

    Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults

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    Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods We used data from 3663 population-based studies with 222 million participants that measured height and weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the individual and combined prevalence of underweight (BMI 2 SD above the median). Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and 140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and 42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents, the increases in double burden were driven by increases in obesity, and decreases in double burden by declining https://researchonline.ljmu.ac.uk/images/research_banner_face_lab_290.jpgunderweight or thinness. Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of underweight while curbing and reversing the increase in obesity

    1593 Chemical Shifts and Coupling Constants for C11H9N2OP

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    3811 Chemical Shifts and Coupling Constants for C16H19N2O4P

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    Effects of Changes in Ownership of the Polish Hospital on the Patients’ Opinion About Its Functioning

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    System changes in health care centers have been directed at introducing such marketing elements into the Polish health care system as managerial approach to managing the centers and contracting medical services and quality management. High quality of the medical services and patients’ satisfaction became the key factors deciding about “the brand” of a health care center. The aim of the work was to assess the effect of changes in ownership of the hospital on the patients’ opinion about its functioning. Patients’ satisfaction survey was carried out through an anonymous questionnaire among 2702 respondents before and 2795 respondents after the transformation of the hospital. Multivariate analysis of variance (MANOVA) was used to analyze the collected empirical material. The assessment of the functioning of the admission center and hospital wards was significantly higher among the respondents asked after the transformation of the hospital as opposed to the assessment before it. Transforming the public hospital in Poland into a commercial company helped improve its functioning in the opinion of patients. There is a need to carry out further systematic research into the patients’ satisfaction better adjust the hospital’s offer to the needs of the hospitalized people

    Factors Influencing the Opinion of Patients Concerning the Functioning of the Polish Hospital Before and After Ownership Transformation

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    Studies of satisfaction among patients are a popular and frequently obligatory tool used in improving the quality of medical services worldwide. Becoming familiar with the opinion of the patients enables to adjust the venue to their expectations, thus contributing to the increase in its competitiveness. We aimed to study patients’ satisfaction understood as a tool used in increasing the quality of medical services; in addition, we assessed factors that affect a worse review patients gave about the functioning of this Polish hospital before and after its transformation into a commercial company. The study of satisfaction among patients was conducted using an anonymous questionnaire among 2702 respondents before and 2795 respondents after the hospital’s transformation. Multivariate logistic regression analysis was applied to statistically analyze the collected empirical material, where the dependent variable was a worse evaluation of respondents concerning the functioning of the hospital. It was demonstrated that both before and after the hospital’s transformation into a commercial company, it was education and conditions of housing of patients that determined their opinion about the functioning of the admission center and hospital wards. A higher level of education increases the risk of a worse evaluation of the admission center and hospital wards, whereas higher self-evaluation of housing conditions lowered the discussed risk. Factors that influence the opinion of patients concerning the functioning of the hospital are education, age, marital status, housing conditions of the respondents and also the number of stays at a given hospital, and a conscious choice of the facility in which a patient wished to be treated

    Homogeneous Catalytic Oxidation of Olefins with Hydrogen Peroxide in the Presence of a Manganese-Substituted Polyoxomolybdate

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    [PMo11Mn(H2O)O-39](5-) is used as catalyst in the homogeneous oxidation of cis-cyclooctene, cyclohexene, styrene, and geraniol with H2O2 in acetonitrile. Oxidation of cis-cyclooctene gives only cyclooctene oxide; cyclohexene-1,2-diol is the main product for cyclohexene; styrene is preferentially oxidized to benzaldehyde; a TOF almost as high as 28800 h(-1) is reached for geraniol oxidation
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