Analisis Pengambilan Keputusan Menerima Atau Menolak Pesanan Khusus Berdasarkan Metode Variable Costing (Studi Pada Perusahaan Mebel Anggun Citra Jati Mas, Bojonegoro Tahun 2013)

Business development is currently very fast, main purpose is a profit. Generally the company meet market demand in the coming years, capacity of unemployed that encourages companies to consider a selling price, in addition cost of good production should be considered. Cost of production can be determined using variable costing method. Variable costing is very useful in the furniture industry. Researchers interested in conducting research on companies Anggun Citra Jati Mas because there is still capacity to be can utilized . The Company may utilize existing capacity by using variable costing method in making decisions to accept the order or reject the order. This study aims to determine the image of a cost analysis using variable costing method in making decisions to accept special orders or reject special order. Type of research with the approach used is descriptive research case study, with documentation and data collection techniques interview. Based on the results of research, can be concluded that using a variable costing methods Anggun Citra Jati Mas company received orders after receiving a special order because profit generated an increased of 50%

MODEL GR4J (Ge’nie Rural a’ 4 Parame’tres Journalier) UNTUK MENDUKUNG ANALISIS KETERSEDIAAN AIR DI DAS TAJUM

This study aims to apply the GR4J model as rainfall-runoff modeling in Tajum watershed to get four free parameters obtained from daily rainfall data. In this study, input data is in the form of daily rainfall data and potential evapotranspiration data. The output of calculated discharged is calibrated using observations of daily discharge data. This modeling optimizes four free parameters of the Maximum Capacity of Production Store (X 1), Groundwater Coefficient (X 2), Maximum Capacity of Routing Store (X 3), and Peak Time of Ordinate Unit Hydrograph (X 4). The optimum values of the modeling parameters of GR4J are obtained from the criterion of the smallest discrepancies between calculated and observed data, which are Nash-Sutcliffe Coefficient (NS), the correlation coefficient values and methods of Relative Volume Error (RVE). There are three stages in this modeling, namely: model calibration, model verification and model validation. Model calibration is carried out by using the first five years of data and verification of models uses the second five years of data. Comparisons of GR4J with other two rainfall-runoff models, Mock and SAC-SMA Models, were also carried. Results of this study indicate that GR4J model shows better performance than the Mock models and SAC-SMA models in terms of the criterion evaluated. Keywords: Tajum watershed, water availability, rainfall-runoff, GR4J model

STRATEGI GURU PENDIDIKAN AGAMA ISLAM DALAM MENCIPTAKAN BUDAYA RELIGIUS DI MADRASAH ALIYAH NEGERI 2 TULUNGAGUNG

ABSTRAK Naila Azizah M.R. Strategi Guru PAI dalam Menciptakan Budaya Religius di Madrasah Aliyah Negeri 2 Tulungagung. Skripsi. Tulungagung : Institut Agama Islam Negeri Tulungagung, 2016. Pembimbing: Dr. H Akhyak, M.Ag. Konteks penelitian ini adalah rusaknya moral bangsa, banyak generasi bangsa usia pelajar melakukan perilaku yang menyimpang bahkan kriminalitas. Padahal proses pembelajaran di sekolah telah melibatkan pendidikan agama dengan tujuan menginternalisasikan nilai-nilai agama baik berupa nilai ketuhanan maupun nilai kemanusiaan kepada peserta didik. Namun ternyata internalisasi nilai agama melalui pembelajaran di dalam kelas saja tidaklah cukup. Oleh karena itu perlu adanya pembelajaran dan bimbingan di dalam maupun di luar kelas dengan penerapan budaya beragama di sekolah. Pembudayaan sikap beragama tersebut bertujuan untuk mencapai keharmonisan dalam menjalani kehidupan dunia dan akhirat. Nilai-nilai agama yang tertanam dalam diri peserta didik tersebut dapat dijadikan pondasi agar mereka tidak keluar dari ajaran-ajaran agama dimanapun dan kapanpun berada. Penelitian ini bersifat kualitatif dengan mengambil latar Madrasah Aliyah Negeri 2 Tulungagung Tulungagung. Pengumpulan data dilakukan dengan cara observasi, wawancara dan dokumentasi. Sedangkan analisis yang digunakan adalah reduksi data, penyajian data dan verifikasi data. Rumusan masalah, 1) Bagaimana strategi guru PAI dalam menciptakan budaya religius di Madrasah Aliyah Negeri 2 Tulungagung? 2) Apa saja bentuk budaya religius dalam bidang ibadah di Madrasah Aliyah Negeri 2 Tulungagung? 3) Apa saja bentuk budaya religius dalam bidang akhlak di Madrasah Aliyah Negeri 2 Tulungagung? Hasil penelitian ini menunjukkan: 1) Terciptanya budaya religius di Madrasah Aliyah Negeri 2 Tulungagung menggunakan model structural melalui kebijakan yang ditetapkan oleh pemimpin madrasah untuk melakukan berbagai upaya sistematis melalui proses internalisasi nilai, keteladanan, pembiasaan, budaya religius dan pada akhirnya tercipta suasana religius; 2) Implementasi budaya religius dalam bidang ibadah terwujud dalam berbagai bentuk aktivitas, antara lain: Berdoa sebelum dan sesudah pembelajaran; Membaca Al-Qur’an dan Asma’ul Husna sebelum memulai pembelajaran; Menghafalkan juz ‘amma; Shalat dhuha, Shalat dzuhur dan sholat Jum’at; Istighotsah; Kegiatan keputrian; dan PHBI (1 Muharram, maulid Nabi, dan isra’ mi’raj); 3) Implementasi budaya religius dalam bidang akhlak terwujud dalam berbagai bentuk aktivitas, antara lain: 5S (Senyum, Salam, Sapa, Sopan dan Santun); Saling menghormati dan menghargai; Selalu menjaga kebersihan dan kelestarian lingkungan

Immunization of AGE-modified albumin inhibits diabetic nephropathy progression in diabetic mice

Musthika Wida Mashitah,1 Nurona Azizah,1 Nur Samsu,2 Muhammad Rasjad Indra,1 Muhammad Bilal,3 Meti Verdian Yunisa,4 Amildya Dwi Arisanti41Department of Biomedicine, Faculty of Medicine, Brawijaya University, Malang, 2Department of Internal Medicine, Division of Nephrology and Hypertension, Saiful Anwar General Hospital, Malang, 3Department of Medicine, Faculty of Medicine, Brawijaya University, Malang, 4Department of Nursing, Faculty of Medicine, Brawijaya University, Malang, IndonesiaBackground: Diabetic nephropathy (DN) is a serious vascular complication of diabetes and an important cause of end-stage renal disease. One mechanism by which hyperglycemia causes nephropathy is through the formation of advanced glycation end products (AGE). Development of vaccination would be a promising therapy for the future, while to date, anti-AGE therapy is based on medicines that are needed to be consumed lifelong. This study aimed to find out the effect of immunization of AGE-modified albumin against DN pathogenesis in streptozotocin-induced diabetic in mice.Methods: We used 24 BALB/c male mice as experimental animals, which were divided into six groups, two nondiabetic groups (negative control and AGE-modified bovine serum albumin [BSA] preimmunized groups) and four streptozotocin-induced diabetic groups (diabetic control group and diabetic preimmunized groups for AGE-BSA, Keyhole limpet hemocyanin (KLH), and AGE-BSA-KLH, respectively).Results: Diabetic preimmunized groups for AGE-BSA, KLH, and AGE-BSA-KLH showed amelioration in renal function and histopathology compared with the diabetic control group. Preimmunization also maintained nephrin intensity and decreased serum AGE level, kidney AGE deposition, and kidney cells apoptosis.Conclusion: AGE-BSA and AGE-BSA-KLH immunizations inhibit the progression of DN. Our results strengthen the evidence that the anti-AGE antibodies have a protective role against diabetic vascular complication, especially DN. This study provides a basis for the development of DN-based immunotherapy with AGE immunization as a potential candidate.Keywords: immunization, advanced glycation end products (AGE), AGE-modified albumin, anti-AGE antibody, diabetic nephropath

Biosensors Based on Nanomaterials: Transducers and Modified Surfaces for Diagnostics

The use of nanoparticles has opened a new era in the development of nanobiosensors capable of achieving analytical responses that compete with the most powerful instrumental techniques. Nanobiosensors are devices that allow analytical determinations through a specific action event between an analyte ofinterest and a bio-recognition molecule. These recognition molecules as enzymes,antibodies, nucleic acids, and aptamers are studied in detail in this chapter. The role of nanomaterials in biosensors is described in a separate section since they play a central role, allowing the understanding of their physicochemical properties such as quantum confinement, surface plasmon resonance, magnetic properties, and the effect of area increase. In addition, a brief review is provided about some basic concepts for the integration of the sensor components and their function in sensing systems found in the literature. Subsequently, a classification is proposed to summarize its fundamental characteristics, mechanism of operation, analytical characteristics, advantages, and disadvantages. Then, the main nanobiosensor types found in the literature are detailed, and specific explanations are given, e.g., those based on the determination of electrical, piezoelectric, colorimetric, fluorescent, and chemiluminescent properties. Likewise, the functioning of recently developed nanobiosensors is discussed, such as those based on local (SERS). Also, the applications of nanobiosensors in different fields of biomedicine and their fundamental importance to advance in the diagnosis of multiple pathologies as cancer are detailed. Finally, we discuss the state of the art and the future perspectives of scientific development.Fil: Romero, Marcelo Ricardo. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; ArgentinaFil: Picchio, Matías Luis. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin