Lateral bed-roughness variation in shallow open-channel flow with very low submergence

Quantifying turbulent fluxes and secondary structures in shallow channel flows is important for predicting momentum and mass transfer in rivers as well as channel capacity and associated water levels. Here, we focus on the flow over a lateral bed-roughness variation with very low relative submergence of the roughness elements, h∕k ={3, 2, 1.5}, where h is the flow depth and k is the roughness height. Measurements were performed in a 1.1 m wide and 26 m long glass flume whose bed was fitted with cubes arranged in two regular side-by-side patterns with frontal densities λf = 0.2 and 0.4 to create a rough-to-rougher variation. Measurements were performed using stereoscopic PIV in two orthogonal planes, in a vertical transverse plane spanning the two roughness types, and in a longitudinal one at the interface between the roughness types. The results show that the bulk velocity difference between the two sides of the channel increases with decreasing h/k. Also, contrary to what is observed at high relative submergence with smooth-to-rough transitions, higher bulk velocities occur on the side with higher roughness. This difference is increasing as the flow becomes shallower and is shown to be due to increasing effective depths ratios, leading to increasingly lower friction factor ratios with lower friction factors on the high-velocity but rougher side. Although increasing streamwise momentum transfer at the interface is needed as h/k decreases, the turbulent and secondary circulation transfer of momentum is increasingly inhibited. A globally-driven secondary-circulation at h∕k = 3 ceases for lower h/k and roughness-scale circulation becomes dominant. Also, even the increased global shear does not lead to large-scale Kelvin Helmholtz instabilities structures. However, the relative importance of the roughness difference on the flow is augmented as the flow becomes shallower and momentum transfer due to lateral dispersive stresses increases

Low relative-submergence effects in a rough-bed open-channel flow

Multi-plane stereoscopic PIV measurements were performed in an open-channel flume fitted with cubes to investigate very low submergence ratios, h/k = {1.5, 2, 3}, where h is the water depth and k the roughness height. The spatial standard deviation of the mean flow components reveals that the extent of the roughness sublayer increases drastically with the decrease in h/k to span the entire water column for the lowest h/k investigated. Despite this, the logarithmic law is still observed on the double-averaged velocity profiles for all h/k, first with a fixed von Kármán constant κ and, second, via the indicator function where κ is a free parameter. Also, the longitudinal and vertical normal stresses indicate a universal boundary layer behaviour independent of h/k. The results suggest that the logarithmic and wake-defect laws can still be applied at such low h/k. However, the lateral normal stress depends on h/k in the range investigated as well as on the geometry of the roughness pattern

Parcours scolaires et modes de transition dans l'enseignement postsecondaire canadien note 4 : Projet Transitions

Note complète ; Résumé ; Capsule ; Full text

Improved methods to produce tissue-engineered skin substitutes suitable for the permanent closure of full-thickness skin injuries

There is a clinical need for skin substitutes to replace full-thickness skin loss. Our group has developed a bilayered skin substitute produced from the patient’s own fibroblasts and keratinocytes referred to as Self-Assembled Skin Substitute (SASS). After cell isolation and expansion, the current time required to produce SASS is 45 days. We aimed to optimize the manufacturing process to standardize the production of SASS and to reduce production time. The new approach consisted in seeding keratinocytes on a fibroblast-derived tissue sheet before its detachment from the culture plate. Four days following keratinocyte seeding, the resulting tissue was stacked on two fibroblast-derived tissue sheets and cultured at the air–liquid interface for 10 days. The resulting total production time was 31 days. An alternative method adapted to more contractile fibroblasts was also developed. It consisted in adding a peripheral frame before seeding fibroblasts in the culture plate. SASSs produced by both new methods shared similar histology, contractile behavior in vitro and in vivo evolution after grafting onto mice when compared with SASSs produced by the 45-day standard method. In conclusion, the new approach for the production of high-quality human skin substitutes should allow an earlier autologous grafting for the treatment of severely burned patients

L’implication des étudiants dans la formation médicale

Objectifs : Présenter un panorama général des diverses modalités selon lesquelles les étudiants s’impliquent dans les réflexions et les décisions académiques relatives à l’organisation des études médicales et présenter les structures institutionnelles dédiées à cette action. Exégèse : Au niveau international, les étudiants en médecine sont regroupés dans la Fédération internationale des associations d’étudiants en médecine (International Federation of Medical Students’ Associations – IFMSA). Celle-ci entretient de multiples relations avec plusieurs organisations dans le domaine de l’enseignement médical, avec l’intention de représenter la voix des étudiants au niveau international (Association pour l’éducation médicale en Europe (Association for medical education in Europe – AMEE), Fédération mondiale pour l’enseignement de la médecine (World Federation of Medical Education – WFME). Au niveau national français, les étudiants en médecine sont représentés par l’ANEMF (Association nationale des étudiants en médecine de France), dont les activités sont présentées dans cet article

Flow structures in a shallow channel with lateral bed-roughness variation

Highly heterogeneous floodplains can give rise to secondary flow structures responsible for the bulk of lateral momentum exchange. Quantifying the redistribution of momentum is required to predict lateral profiles of flow velocity and the associated water level in a river. In the work herein, we focus on studying secondary flow structures and the momentum redistribution associated with a lateral bed-roughness variation in a channel with low relative submergence of the roughness elements, h=k = 3, 2 and 1.5, where h is the flow depth and k is the roughness height. A series of laboratory experiments were performed in a flume containing rows of cubes. They were arranged in two types of regular patterns, with higher and lower frontal density, and placed side by side such that the bed roughness varies in the lateral direction. The measurements were performed using stereoscopic PIV in a vertical cross plane spanning between the two roughness types. The time-averaged and turbulence statistics of the three components of the velocity field were analyzed. First, we focus on the intensity of the secondary currents. As the flow becomes shallower (lower relative submergence), the cross-stream velocity normalized by the streamwise velocity increases. A large-scale secondary current at the border between the two roughnesses as observed in [1] (though in their case between smooth and rough regions) appears for h=k = 3. As h=k decreases, this structure reaches to the same size as the secondary flow generated by the roughness elements. Also, the discharge distribution between the two sides of the channel becomes less uniform with decreasing h=k. In this sense, the relative importance of the roughness difference increases with decreasing water depth. Moreover, higher discharge is observed on the side with higher equivalent sand roughness, contrary to what is observed for smooth-to-rough transition [1, 2]. Time series of the streamwise velocity fluctuations are calculated using Taylor’s “frozen turbulence” hypothesis. In this representation, streamwise velocity streaks are apparent for h=k = 3, but they appear to lose coherence for the most shallow case of h=k=1.5