20 research outputs found
A Survey on the Security and the Evolution of Osmotic and Catalytic Computing for 5G Networks
The 5G networks have the capability to provide high compatibility for the new
applications, industries, and business models. These networks can tremendously
improve the quality of life by enabling various use cases that require high
data-rate, low latency, and continuous connectivity for applications pertaining
to eHealth, automatic vehicles, smart cities, smart grid, and the Internet of
Things (IoT). However, these applications need secure servicing as well as
resource policing for effective network formations. There have been a lot of
studies, which emphasized the security aspects of 5G networks while focusing
only on the adaptability features of these networks. However, there is a gap in
the literature which particularly needs to follow recent computing paradigms as
alternative mechanisms for the enhancement of security. To cover this, a
detailed description of the security for the 5G networks is presented in this
article along with the discussions on the evolution of osmotic and catalytic
computing-based security modules. The taxonomy on the basis of security
requirements is presented, which also includes the comparison of the existing
state-of-the-art solutions. This article also provides a security model,
"CATMOSIS", which idealizes the incorporation of security features on the basis
of catalytic and osmotic computing in the 5G networks. Finally, various
security challenges and open issues are discussed to emphasize the works to
follow in this direction of research.Comment: 34 pages, 7 tables, 7 figures, Published In 5G Enabled Secure
Wireless Networks, pp. 69-102. Springer, Cham, 201
Gut microbiota in experimental murine model of Graves’ orbitopathy established in different environments may modulate clinical presentation of disease
Background
Variation in induced models of autoimmunity has been attributed to the housing environment and its effect on the gut microbiota. In Graves’ disease (GD), autoantibodies to the thyrotropin receptor (TSHR) cause autoimmune hyperthyroidism. Many GD patients develop Graves’ orbitopathy or ophthalmopathy (GO) characterized by orbital tissue remodeling including adipogenesis. Murine models of GD/GO would help delineate pathogenetic mechanisms, and although several have been reported, most lack reproducibility. A model comprising immunization of female BALBc mice with a TSHR expression plasmid using in vivo electroporation was reproduced in two independent laboratories. Similar orbital disease was induced in both centers, but differences were apparent (e.g., hyperthyroidism in Center 1 but not Center 2). We hypothesized a role for the gut microbiota influencing the outcome and reproducibility of induced GO.
Results
We combined metataxonomics (16S rRNA gene sequencing) and traditional microbial culture of the intestinal contents from the GO murine model, to analyze the gut microbiota in the two centers. We observed significant differences in alpha and beta diversity and in the taxonomic profiles, e.g., operational taxonomic units (OTUs) from the genus Lactobacillus were more abundant in Center 2, and Bacteroides and Bifidobacterium counts were more abundant in Center 1 where we also observed a negative correlation between the OTUs of the genus Intestinimonas and TSHR autoantibodies. Traditional microbiology largely confirmed the metataxonomics data and indicated significantly higher yeast counts in Center 1 TSHR-immunized mice. We also compared the gut microbiota between immunization groups within Center 2, comprising the TSHR- or βgal control-immunized mice and naïve untreated mice. We observed a shift of the TSHR-immunized mice bacterial communities described by the beta diversity weighted Unifrac. Furthermore, we observed a significant positive correlation between the presence of Firmicutes and orbital-adipogenesis specifically in TSHR-immunized mice.
Conclusions
The significant differences observed in microbiota composition from BALBc mice undergoing the same immunization protocol in comparable specific-pathogen-free (SPF) units in different centers support a role for the gut microbiota in modulating the induced response. The gut microbiota might also contribute to the heterogeneity of induced response since we report potential disease-associated microbial taxonomies and correlation with ocular disease
Effect of Nitrogen on Weed Infestation and Performance of Boro Rice Under Two Selected Herbicides
A field experiment was conducted at the experimental farm of Bangabandhu Sheikh Mujibur Rahman Agricultural University (BSMRAU), Salna, Gazipur from November 2013 to May 2014 to determine the effect of nitrogen and herbicide on weed infestation and performance of Boro rice (cv. BRRIdhan28). Five nitrogen doses i.e. 0 , 50.6 , 101.2 , 151.8 and 202.4 kg ha-1 under selected pre-emergence and post-emergence herbicides along with one weed free and control (unweeded) treatment were imposed in the experiment. Nine weed species was found to dominate in the experimental plots where Scirpus maritimus L. showed the maximum visual abundance (58%) followed by Leersia hexandra sw., Paspalam distichum L. and Fimbristylis miliacea L. Post-emergence herbicide contributed to higher control efficiency than that in pre-emergence herbicide. Post-emergence herbicide without receiving nitrogen showed the highest weed control efficiency (97.39) at 60 days after transplanting. Treatment receiving N @ 200.4 kg ha-1 under post-emergence herbicide showed the highest number of tiller per hill (13.00), total dry matter (1568.6 g m-2), panicles per hill (10.60), filled grains per panicle (125.20) and grain yield (6.46 t/ha). N-dose 151.8 kg ha-1 under postemergence herbicide contributed to the second highest grain yield (6.41 t ha-1) with the highest benefit cost ratio of 1.60 but 50.6 kg N ha-1 under post-emergence herbicide showed the maximum Nitrogen use efficiency of 0.49. The study revealed that nitrogen dose up to 151.8 kg ha-1 might be increased above the recommended dose under coverage of a suitable post-emergence herbicide for profitable rice production