Tardive hip disease diagnosis in a young adult with sickle cell disease

Background:Hip disease is a complication of Sickle Cell Disease most commonly occurs during adolescence and early adult life that constitutes from 3.3% to 26.7% % of cases in SCD patients. Damage to mature epiphysis may cause persistent symptoms requiring surgery which may need revision if it becomes loose with wear. Case Presentation:We report a 27-year-old male who was diagnosed with hip disease following investigations for persistent pain in right hip associated with limp and painful limitation of movement. Avascular necrosis of the right femoral head was identified on a hip X-ray. Conclusion:Further investigation will be necessary to identify risk factors in SCD Congolese patient and each SCD patient must be screened for predisposing factors

Blackwater fever in Congolese children: a report of clinical, laboratory features and risk factors

BACKGROUND: Blackwater fever (BWF) is one of the severe forms of malaria. This complication was first described among non-immune European expatriates in the malaria endemic areas. Recently, resurgence of this form of malaria has been reported among the indigenous populations. The objective of this study was to investigate the risk factors among BWF patients. METHODS: A case-control study was conducted between in four hospitals located in Kinshasa, Democratic Republic of Congo from January 2010 to December 2011. One hundred and twenty nine children were recruited with 43 (cases) and 86 (control). RESULTS: No significant difference in the gender and age distribution was observed between the case and control). The sex-ratio male to female in the case group and control group was respectively 1:1.0 and 1:1.1. The mean age was 8.62 years (SD = 3.84) in patients with haemoglobinuria and 8.55 years (SD = 3.77) in the control group. No difference in frequency of co-infection with Plasmodium falciparum and Plasmodium malariae was observed between the two groups. Significant differences in haemoglobin, haematocrit, creatinine, urea and platelets levels were observed between the two groups (p < 0.001), but not for blood group and lactate dehydrogenase (LDH) level. Majority of the BWF cases occurred during the rainy season (88.4%). Treatment with quinine (95.3%) was significantly associated with cases (p < 0.001). Seven (16.2%) of the haemoglobinuric children developed acute renal failure. CONCLUSION: Rainy season, low parasitaemia and quinine ingestion were the major risk factors significantly associated with haemoglobinuria. Acute renal failure was observed as the major complication of BWF.status: publishe