392 research outputs found
Surface inorganic scale formation in oil and gas industry: As adhesion and deposition processes
Scale formation on surfaces can normally be divided into two distinct processes: a “deposition process” which refers to the process of heterogeneous nucleation and growth at the asperities of the surface and an “adhesion process” which refers to the sticking of pre-existing crystals, which have nucleated in the bulk solution, and which build up as a layer on the surface. It has been presented in this paper that the surface scale formation rate is more dominantly controlled by the “deposition process” rather than the “adhesion process”. However, the level of agitation could have inverse effects on one process to another. Only a small amount of research has been done to understand the differences of the kinetics of each of these processes. The presented work represents an experimental study of scaling tests to assess the effect of hydrodynamic conditions, using Rotating Cylinder Electrode (RCE), in a complex scaling environment, particularly supersaturated with barium/strontium sulphate and calcium carbonate, on the stainless steel substrate coated with a wide range of different industrial coatings. In addition, the effect of the surface energy and surface roughness on both processes has been studied. The paper provides data that will assist in the understanding of the controlling parameters in scale formation in different conditions, and also describes what characteristics of the surface can make it a good anti-scale surface for inorganic scale; however, the results have showed that merely one parameter cannot assure a surface as a good antifouling surface
Roles of Transcriptional and Translational Control Mechanisms in Regulation of Ribosomal Protein Synthesis in Escherichia coli
Intelligence and memory outcomes within 10 years of childhood convulsive status epilepticus
Long-term intelligence and memory outcomes of children post convulsive status epilepticus (CSE) have not been
systematically investigated despite evidence of short-term impairments in CSE. The present study aimed to describe intelligence and memory outcomes in children within 10 years of CSE and identify potential risk factors for
adverse outcomes. In this cohort study, children originally identified by the population-based North London Convulsive Status Epilepticus in Childhood Surveillance Study (NLSTEPSS) were prospectively recruited between
July 2009 and February 2013 and invited for neuropsychological assessments and magnetic resonance imaging
(MRI) scans. Full-scale intelligence quotients (FSIQs) were measured using the Wechsler Abbreviated Scales of
Intelligence (WASI), and global memory scores (GMS) was assessed using the Children's Memory Scale (CMS).
The cohort was analyzed as a whole and stratified into a prolonged febrile seizures (PFS) and non-PFS group.
Their performance was compared with population norms and controls. Regression models were fitted to identify
predictors of outcomes. With a mean of 8.9 years post-CSE, 28.5% of eligible participants were unable to undertake testing because of their severe neurodevelopmental deficits. Children with CSE who undertook formal testing (N = 94) were shown to have significantly lower FSIQ (p = 0.001) and GMS (p = 0.025) from controls; the
PFS group (N = 34) had lower FSIQs (p = 0.022) but similar memory quotients (p = 0.88) with controls. Intracranial volume (ICV), developmental delay at baseline, and active epilepsy at follow-up were predictive of longterm outcomes in the non-PFS group. The relationship between ICV and outcomes was absent in the PFS group
despite its presence in the control and non-PFS groups. Post-CSE, survivors reveal significant intelligence and
memory impairments, but prognosis differs by CSE type; memory scores are uncompromised in the PFS group
despite evidence of their lower FSIQ whereas both are compromised in the non-PFS group. Correlations between
brain volumes and outcomes differ in the PFS, non-PFS, and control groups and require further investigatio
Lignin-derived electrospun freestanding carbons as alternative electrodes for redox flow batteries
Based on information provided the embargo period/end date is 12 monthsBased on information provided the embargo period/end date is 12 month
Tumours and tumour-like lesions of the lower face at Korle Bu Teaching Hospital, Ghana – an eight year study
<p>Abstract</p> <p>Background</p> <p>The oro-facial region including the jawbones, the maxilla and mandible and related tissues can be the site of a multitude of neoplastic conditions. These tumours have a predilection for the entire facial region; however, odontogenic tumours tend to affect the mandible more than the maxilla, especially, in West African children. We report results from a retrospective study spanning eight years on the frequency, clinical presentation, sites and character of lower face tumours seen in the main referral hospital in Ghana.</p> <p>Patients and methods</p> <p>Records of consecutive patients of all age and sex seen by the first author's team at the Department of Oral and Maxillofacial Surgery, Korle-Bu Teaching Hospital with tumours affecting the lower part of the face from January 1996 to December 2003 were retrieved, coded and entered into a database. The data were then analyzed by age, sex, presenting signs and symptoms, site of lesion, and their histology.</p> <p>Results</p> <p>A total of 394 patients with oro-facial swellings were retrieved from the registry out of which 210 had lower face tumour and tumour-like lesions. The complete data set was obtained for 171 patients, comprising 99 (58%) males and 72 (42%) females. The most common clinical presenting features were mandibular facial swelling (63%), intra-oral swelling (55%), pain (41%) and ulceration (29%). The tumours were predominantly found in the right (43%), anterior (19%) and left (18%) aspects of the lower face. The remainder making up 20% were found in the floor of the mouth, tongue and lips. Seventy eight (45.6%) of the patients presented with lesions that were classified as malignant of which 54 (62%) were diagnosed as squamous cell carcinoma (SCC). Sixty-two (36.3%) had benign odontogenic tumours and thirty-one (18.1%) had non-odontogenic tumour-like lesions. Fifty-four (62%) of malignant tumours were squamous cell carcinoma; 58 (93.6%) of the benign odontogenic tumours were classified as ameloblastoma. The mean age at presentation of all lesions was 40.4 years with over 50% of benign lesions in patients aged between 11 and 30 years. Malignant tumours were more commonly detected in patients between 41 and 70 years (63%).</p> <p>Conclusion</p> <p>Tumours and tumour-like lesions of the lower face comprising the mandible, tongue and adjacent structures are a diverse group of neoplasm and are seen commonly in practice of Maxillofacial surgery. Both malignant and benign tumours are seen in the Ghanaian population. In the present study, SCC and ameloblastoma were the commonest malignant and benign odontogenic tumours seen respectively; the two representing more than 65% of all tumours.</p
Early developmental outcomes in children following convulsive status epilepticus: a longitudinal study
Convulsive status epilepticus (CSE) is the most common pediatric neurologic emergency and is often associated with unfavorable neurodevelopmental outcomes. The early developmental trajectory of children following CSE has not been previously investigated, leaving a gap in our understanding of how these adverse long-term outcomes emerge
Perturbative quantum gravity with the Immirzi parameter
We study perturbative quantum gravity in the first-order tetrad formalism.
The lowest order action corresponds to Einstein-Cartan plus a parity-odd term,
and is known in the literature as the Holst action. The coupling constant of
the parity-odd term can be identified with the Immirzi parameter of loop
quantum gravity. We compute the quantum effective action in the one-loop
expansion. As in the metric second-order formulation, we find that in the case
of pure gravity the theory is on-shell finite, and the running of Newton's
constant and the Immirzi parameter is inessential. In the presence of fermions,
the situation changes in two fundamental aspects. First, non-renormalizable
logarithmic divergences appear, as usual. Second, the Immirzi parameter becomes
a priori observable, and we find that it is renormalized by a four-fermion
interaction generated by radiative corrections. We compute its beta function
and discuss possible implications. The sign of the beta function depends on
whether the Immirzi parameter is larger or smaller than one in absolute value,
and the values plus or minus one are UV fixed-points (we work in Euclidean
signature). Finally, we find that the Holst action is stable with respect to
radiative corrections in the case of minimal coupling, up to higher order
non-renormalizable interactions.Comment: v2 minor amendment
Lung carcinoma with hypertrophic osteoarthropathy in a teenager
Hypertrophic osteoarthropathy (HOA) characterised by arthralgia, clubbing and periosteal proliferation of long bones, is rarely encountered in children and adolescents. Whereas in adults over 80% of cases are associated with malignancy, in children the majority of cases are due to non-neoplastic causes such as cystic fibrosis, bilary atresia and congenital heart disease. Up to 5% of adults with lung cancer demonstrate signs of HOA. However, lung cancer is extremely uncommon in children and young people. Here we report a case of lung adenocarcinoma in an 18 year old male associated with HOA present both at diagnosis and at subsequent disease progression
Identification and characterization of a novel non-structural protein of bluetongue virus
Bluetongue virus (BTV) is the causative agent of a major disease of livestock (bluetongue). For over two decades, it has been widely accepted that the 10 segments of the dsRNA genome of BTV encode for 7 structural and 3 non-structural proteins. The non-structural proteins (NS1, NS2, NS3/NS3a) play different key roles during the viral replication cycle. In this study we show that BTV expresses a fourth non-structural protein (that we designated NS4) encoded by an open reading frame in segment 9 overlapping the open reading frame encoding VP6. NS4 is 77–79 amino acid residues in length and highly conserved among several BTV serotypes/strains. NS4 was expressed early post-infection and localized in the nucleoli of BTV infected cells. By reverse genetics, we showed that NS4 is dispensable for BTV replication in vitro, both in mammalian and insect cells, and does not affect viral virulence in murine models of bluetongue infection. Interestingly, NS4 conferred a replication advantage to BTV-8, but not to BTV-1, in cells in an interferon (IFN)-induced antiviral state. However, the BTV-1 NS4 conferred a replication advantage both to a BTV-8 reassortant containing the entire segment 9 of BTV-1 and to a BTV-8 mutant with the NS4 identical to the homologous BTV-1 protein. Collectively, this study suggests that NS4 plays an important role in virus-host interaction and is one of the mechanisms played, at least by BTV-8, to counteract the antiviral response of the host. In addition, the distinct nucleolar localization of NS4, being expressed by a virus that replicates exclusively in the cytoplasm, offers new avenues to investigate the multiple roles played by the nucleolus in the biology of the cell
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