Study on the growth and development of brinjal shoot and fruit borer with different diets

A laboratory experiment was conducted with two natural and one artificial diet on the growth and development of brinjal shoot and fruit borer (BSFB). The population of BSFB used in the study was in the 2nd instar larvae. Among the different diet, brinjal was the best for growth, development and longevity of larvae and pupae and prolongation of larval and pupal period. The mean length of full grown larvae fed with natural the food brinjal were 9.37, 9.80 and 12.44 mm from generations 1, 2 and 3, respectively. The larval and pupal duration on brinjal food media were 13.10 and 8.17, 12.80 and 8.23 and 13.10 and 8.03 days in generations 1, 2 and 3, respectively. The percentages of adult emergence from pupae raised in brinjal were 65.38, 47.95 and 33.78 in generations 1, 2 and 3, respectively.Key words: Brinjal, brinjal shoot and fruit borer (BSFB), natural and artificial diet

Komunikasi Pemasaran Terpadu Roti Ganep (Studi Deskriptif Kualitatif Komunikasi Pemasaran Terpadu Perusahaan Roti Ganep Solo)

Industri makanan ringan saat menjadi potensi bisnis yang menguntungkan. Perusahaan Roti Ganep sendiri merupakan perusahaan yang sudah puluhan tahun menjadi produsen roti di kota Solo. Kegiatan komunikasi yang dilakukan Ganep dalam rangka mempromosikan serta menjaga pangsa pasar khususnya di kota Solo Misalnya penjualan personal (personal selling), promosi penjualan (sales promotion), humas (public relations), media internet melalui website dan direct marketing. Komunikasi pemasaran terpadu adalah bagaimana suatu keterpaduan dari komunikasi yang erat kaitanya dengan komunikasi. Untuk itu dalam menganalisisnya digunakan studi deskriptif, peneliti bertindak sebagai pengamat, hanya membuat kategori perilaku, mengamati gejala dan mencatatnya dalam observasinya. Sedangkan menggunakan metode kualitatif, penelitian kualitatif merupakan penelitian yang belum ada teorinya sehingga peneliti harus berusaha menemukan teori tersebut. Di mana dalam setiap bidang-bidang dalam komunikasi pemasaran terpadu merupakan strategi yang digunakan oleh perusahaan Ganep saat ini. Kesimpulan yang dapat disimpulkan dalam penelitian ini bahwa strategi komunikasi pemasaran terpadu yang dilakukan oleh Perusahaan Ganep selama ini bisa dikatakan berjalan dengan lancar. Strategi pemasaran yang dilakukan pihak menejemen dalam mempromosikan produk dari Ganep dengan menerapkan komunikasi pemasaran terpadu mampu bersaing dengan perusahaan lain. Selain itu Ganep meluncurkan website di rotiganep.com. Menurut perusahaan hal tersebut dinilai berhasil mengingat jumlah konsumen yang mengalami peningkatan

Space Efficient Breadth-First and Level Traversals of Consistent Global States of Parallel Programs

Enumerating consistent global states of a computation is a fundamental problem in parallel computing with applications to debug- ging, testing and runtime verification of parallel programs. Breadth-first search (BFS) enumeration is especially useful for these applications as it finds an erroneous consistent global state with the least number of events possible. The total number of executed events in a global state is called its rank. BFS also allows enumeration of all global states of a given rank or within a range of ranks. If a computation on n processes has m events per process on average, then the traditional BFS (Cooper-Marzullo and its variants) requires $\mathcal{O}(\frac{m^{n-1}}{n})$ space in the worst case, whereas ou r algorithm performs the BFS requires $\mathcal{O}(m^2n^2)$ space. Thus, we reduce the space complexity for BFS enumeration of consistent global states exponentially. and give the first polynomial space algorithm for this task. In our experimental evaluation of seven benchmarks, traditional BFS fails in many cases by exhausting the 2 GB heap space allowed to the JVM. In contrast, our implementation uses less than 60 MB memory and is also faster in many cases

Integrated Marketing Communication Strategy Of Sfa Steak And Resto In Facing Competition In Solo

This study uses a theoretical approach of integrated marketing communication strategy (IMC) Terence A. The purpose of this research is to see integrated marketing communication activities that are run by SFA Steak and Resto and what strategies are used to face the competition especially in Solo city. This research uses descriptive qualitative methods, techniques of collecting data through interviews, documentation, and literature studies. In determining informants, this study uses purposive sampling technique. In data validation, this study uses data source triangulation. The results of this study show that the integrated marketing communication strategy carried out by SFA Steak and Resto are advertising, sales promotion, direct marketing, public relations and personal selling. It is a way to deal with existing competition and attract and retain consumer interest. From existing mixtures, SFA Steak and Resto uses a lot of sales promotion mix. Besides integrated marketing communication strategy, SFA Steak and Resto uses other strategies that are segmentation and target strategies

Assessing Mechanical Properties of Jute, Kenaf, and Pineapple Leaf Fiber-Reinforced Polypropylene Composites: Experiment and Modelling

The application of natural fibers is increasing rapidly in the polymer-based composites. This study investigates manufacturing and characterization of polypropylene (PP) based composites reinforced with three different natural fibers: jute, kenaf, and pineapple leaf fiber (PALF). In each case, the fiber weight percentages were varied by 30 wt.%, 35 wt.%, and 40 wt.%. Mechanical properties such as tensile, flexural, and impact strengths were determined by following the relevant standards. Fourier transform infrared (FTIR) spectroscopy was employed to identify the chemical interactions between the fiber and the PP matrix material. Tensile strength and Izod impact strength of the composites significantly increased for all the composites with different fiber contents when compared to the pure PP matrix. The tensile moduli of the composites were compared to the values obtained from two theoretical models based on the modified “rule of mixtures” method. Results from the modelling agreed well with the experimental results. Tensile strength (ranging from 43 to 58 MPa), flexural strength (ranging from 53 to 67 MPa), and impact strength (ranging from 25 to 46 kJ/m2) of the composites significantly increased for all the composites with different fiber contents when compared to the pure PP matrix having tensile strength of 36 MPa, flexural strength of 53 Mpa, and impact strength of 22 kJ/m2. Furthermore, an improvement in flexural strength but not highly significant was found for majority of the composites. Overall, PALF-PP displayed better mechanical properties among the composites due to the high tensile strength of PALF. In most of the cases, T98 (degradation temperature at 98% weight loss) of the composite samples was higher (532–544 °C) than that of 100% PP (500 °C) matrix. Fractured surfaces of the composites were observed in a scanning electron microscope (SEM) and analyses were made in terms of fiber matrix interaction. This comparison will help the researcher to select any of the natural fiber for fiber-based reinforced composites according to the requirement of the final product

Assessment of left ventricular volumes using simplified 3-D echocardiography and computed tomography – a phantom and clinical study

<p>Abstract</p> <p>Objectives</p> <p>To compare the accuracy of simplified 3-dimensional (3-D) echocardiography vs. multi-slice computed tomography (MSCT) software for the quantification of left ventricular (LV) volumes.</p> <p>Design</p> <p>Three-D echocardiography (3-planes approach) and MSCT-CardIQ software were calibrated by measuring known volumes of 10 phantoms designed to closely mimic blood-endocardium interface. Subsequently, LV volumes were measured with both the methods in 9 patients referred routinely for coronary angiography and the agreement between the measurements was evaluated.</p> <p>Results</p> <p>Simplified 3D-echocardiography provided higher degree of agreement between the measured and true phantom volumes (mean difference 0 ± 1 ml, variation range +4 to -4 ml) than MSCT software (mean difference 6 ± 5 ml; variation range +22 to -10 ml). The agreement between LV measurements in the patients was considerably poorer, with significantly larger volumes produced by MSCT (mean difference -23 ± 40 ml, variation between +93 and -138 ml).</p> <p>Conclusion</p> <p>Simplified 3-D echocardiography provides more accurate assessment of phantom volumes than MSCT-CardIQ software. The discrepancy between the results of LV measurements with the two methods is even greater and does not warrant their interchangeable diagnostic use.</p

Treatment of developmental dyslexia: A review

Remarkably few research articles on the treatment of developmental dyslexia were published during the last 25 years. Some treatment research arose from the temporal processing theory, some from the phonological deficit hypothesis and some more from the balance model of learning to read and dyslexia. Within the framework of that model, this article reviews the aetiology of dyslexia sub-types, the neuropsychological rationale for treatment, the treatment techniques and the outcomes of treatment research. The possible mechanisms underlying the effects of treatment are discussed. © 2005 Informa UK Ltd All rights reserved

Zilucoplan in immune-mediated necrotising myopathy: a phase 2, randomised, double-blind, placebo-controlled, multicentre trial

BACKGROUND: Immune-mediated necrotising myopathy is an autoimmune myopathy characterised by proximal muscle weakness, high creatine kinase concentrations, and autoantibodies recognising 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) or the signal recognition particle (SRP). No approved therapies exist for people with immune-mediated necrotising myopathy. Previous studies have suggested that complement activation might be pathogenic in immune-mediated necrotising myopathy; therefore, zilucoplan, a complement C5 (C5) inhibitor, could be a potential therapy. We aimed to evaluate the efficacy, safety, and tolerability of zilucoplan in adult participants with anti-HMGCR or anti-SRP autoantibody-positive immune-mediated necrotising myopathy. METHODS: IMNM-01 was a phase 2, multicentre, randomised, double-blind, placebo-controlled study done at 15 hospital sites across the USA, the UK, France, and the Netherlands. Participants aged 18–74 years were eligible for inclusion if they had a clinically confirmed diagnosis of immune-mediated necrotising myopathy, positive serology for anti-HMGCR or anti-SRP autoantibodies, clinical evidence of weakness, serum total creatine kinase concentration of more than 1000 U/L at screening, and no change in glucocorticoids or other immunosuppressive therapies for 30 days before baseline or expected during the first 8 weeks of the study. Participants were randomly assigned (1:1) to receive daily subcutaneous zilucoplan (0·3 mg/kg) or placebo for 8 weeks by use of a computerised randomisation algorithm; with optional enrolment in the study open-label extension. Randomisation was stratified by autoantibody status. Participants and study staff were masked to treatment group assignment. Primary efficacy endpoint (in the intent-to-treat population, defined as all participants who were randomly assigned to a treatment group) was percent change from baseline to week 8 in creatine kinase concentrations. Safety analyses were performed on the safety population (participants who received at least one dose of study drug during the main study, irrespective of whether they continued to the extension period—study participants were analysed on the basis of the treatment received). This study is registered with ClinicalTrials.gov, NCT04025632. FINDINGS: Between Nov 7, 2019, and Jan 7, 2021, we randomly assigned 27 participants (13 female and 14 male) to receive zilucoplan (n=12) or placebo (n=15). All 27 participants completed the 8-week main study. At week 8 there were no significant differences between treatment groups in median percent change of creatine kinase concentrations versus baseline (–15·1% [IQR –31·1 to 3·2] in the zilucoplan group vs –16·3% [–43·8 to 5·9] in the placebo group; p=0·46) and no clinically relevant improvement over time within the treatment group despite target engagement based on mode of action. There were no unexpected adverse safety or tolerability findings. Treatment-emergent adverse events were reported in nine (75%) of 12 participants in the zilucoplan group, and in 13 (87%) of 15 participants in the placebo group, and serious treatment-emergent adverse events were reported in zero participants in the zilucoplan group and three (20%) participants in the placebo group. The most frequent treatment-emergent adverse events were headache (four [33%] participants in the zilucoplan group and four [27%] participants in the placebo group) and nausea (three [25%] participants in the zilucoplan group and three [20%] participants in the placebo group). INTERPRETATION: C5 inhibition does not appear to be an efficacious treatment modality for people with immune-mediated necrotising myopathy. Rather than being the primary driver for disease activity, complement activation might be secondary to muscle injury. FUNDING: Ra Pharmaceuticals (now part of UCB Pharma)