Spatial Modulation or Spatial Multiplexing for mmWave Communications?

In this paper, two large scale (LS)–multiple–input multiple–output (MIMO) systems and their performance over 3D statistical outdoor millimeter wave (mmWave) channel model are considered and thoroughly analyzed. Namely, spatial multiplexing (SMX) and spatial modulation (SM) systems are considered. The performance of both systems in terms of average bit error ratio (ABER) and channel capacity are derived and studied. Obtained results divulge that SM can achieve higher theoretical capacity than SMX system. Further, SMX system is shown to offer better ABER and mutual information performance as compared to SM system for the same system configuration. Yet, SM demonstrate significant energy efficiency (EE) enhancement for large scale number of transmit antennas.© 2019 Springer. ICST Institute for Computer Sciences, Social Informatics and Telecommunications Engineering.fi=vertaisarvioitu|en=peerReviewed

Professional development and sustainable development goals

Professional development is defined as a consciously designed systematic process that helps professionals to attain, utilize, and retain knowledge, skills, and expertise. It is simply a process of obtaining skills, qualifications, and experience that help in advancement in one’s career. In the field of education, it is defined as the process of improving staff skills and competencies needed to produce outstanding performance of students. It also refers to a process of improving an organization’s staff capabilities through access to education and training opportunities for better output. Professional development can include a variety of approaches such as formal and informal education, vocational, specialized, or skill-based training, or advanced professional learning

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

Cisplatin and its platinum analogs, carboplatin and oxaliplatin, are some of the most widely used cancer chemotherapeutics. Although cisplatin and carboplatin are used primarily in germ cell, breast and lung malignancies, oxaliplatin is instead used almost exclusively to treat colorectal and other gastrointestinal cancers. Here we utilize a unique, multi-platform genetic approach to study the mechanism of action of these clinically established platinum anti-cancer agents, as well as more recently developed cisplatin analogs. We show that oxaliplatin, unlike cisplatin and carboplatin, does not kill cells through the DNA-damage response. Rather, oxaliplatin kills cells by inducing ribosome biogenesis stress. This difference in drug mechanism explains the distinct clinical implementation of oxaliplatin relative to cisplatin, and it might enable mechanistically informed selection of distinct platinum drugs for distinct malignancies. These data highlight the functional diversity of core components of front-line cancer therapy and the potential benefits of applying a mechanism-based rationale to the use of our current arsenal of anti-cancer drugs

An e-tourism adoption model and its implications for tourism industry in Nepal

Although Nepal has tremendous tourism opportunities, the small and medium tourism enterprises (SMTEs) that constitute the largest percentage of tourism service providers, are lagging behind in e-Tourism adoption. This research conducts a comprehensive analysis of existing literature to propose an e-Tourism adoption model based on the Technology-Organisation-Environment and e-Readiness models. This model is supported by empirical data using qualitative in-depth interviews with seven key stakeholders and quantitative survey with 198 SMTEs. An operational model is outlined to identify the barriers and motivators for e-Tourism adoption in Nepal. Implications of this model for key stakeholders such as the government, tourism organisations and tourism associations are discussed. As Nepal moves to a federal political structure, the findings and recommendation from this research are expected to help policy makers, tourism associations and SMTEs to develop specific e-Tourism based programs in order to provide superior services to tourists