74 research outputs found

    SOUVENIR ALL INDIA COORDINATED RESEARCH PROJECT FOR DRYLAND AGRICULTURE CRIDA, HYDERABAD XV Working Group Meeting (24th-27th December, 2015) BISWANATH CHARIALI CENTRE ASSAM AGRICULTURAL UNIVERSITY

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    Not AvailableIt is my proud privilege to express heartfelt thanks to the entire AICRPDA family for giving me the responsibility of bringing out a souvenir to commemorate the occasion of XVth Working Group Meeting of AICRPDA at Biswanath Chariali Centre, BNCA, Assam Agricultural University. I, on behalf of the editorial board do extend a warm welcome to all delegate scientists and dignitaries coming from different parts of our country to this holy historic place of Biswanath, popularly known as ‘Gupta Kanshi’. Holding such a mega event of national importance for the first time at a place like Biswanath Chariali at the far east of the country amidst the bounty of natural resources and an area being almost entirely rainfed is of great significance. In view of the aim of realizing the dream of another green revolution that is envisaged from the rainfed areas of the country particularly the eastern and north eastern parts; this workshop is expected to march ahead further for achieving the goal. The vast ‘Gene’ resource of the North East India offers plenty of scope for their utilization to cope up the challenges of rainfed agriculture. This is a challenging task of converting these ‘Gene’ resources into viable ‘Seed Resources’ for their commercial exploitation keeping the very natural resource base and integrity unaltered. A holistic effort with all modern technological interventions is the need of the hour to bring into sustainable utilization of the natural resource base of the region. The idea of bringing out the souvenir in its present form came with the realization of the need of accumulating the multitude of the concepts required for framing the objectives of rainfed area research particularly for the North Eastern part of India. I am fortunate to have the wholehearted response from many luminaries from several ICAR institutes including CRIDA and number dignified scientists from the Assam Agricultural University contributing their valuable articles. I, do express gratitude and thankfulness from my inner core of the heart to all of them for their valuable contributions. I am extremely grateful to the Honorable Vice Chancellor, AAU, Dr. Kamalmalla Bujarbaruah sir, for his constant inspiration and suggestions all along the organization of the workshop. I would also like to express my sincere gratitude to Dr. Srinivasa Rao, Director, CRIDA, Dr. G. N. Hazarika, Director of Research (Agri), AAU, Dr.G.Rabindra Charry, PC, AICRPDA, Dr. T.C. Baruah, Associate Dean, BNCA, Dr. P.K. Sarma, CS, AICRPDA and all associated scientists for their encouragement, moral support and valuable suggestions. Last but not the least, all the Research Associates working under AICRPDA, BNCA, do deserve due share of thanks for their all round helps in bringing out the souvenir.Not Availabl

    Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer

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    Background Limitless self-renewal is one of the hallmarks of cancer and is attained by telomere maintenance, essentially through telomerase (hTERT) activation. Transcriptional regulation of hTERT is believed to play a major role in telomerase activation in human cancers. Main body The dominant interest in telomerase results from its role in cancer. The role of telomeres and telomere maintenance mechanisms is well established as a major driving force in generating chromosomal and genomic instability. Cancer cells have acquired the ability to overcome their fate of senescence via telomere length maintenance mechanisms, mainly by telomerase activation. hTERT expression is up-regulated in tumors via multiple genetic and epigenetic mechanisms including hTERT amplifications, hTERT structural variants, hTERT promoter mutations and epigenetic modifications through hTERT promoter methylation. Genetic (hTERT promoter mutations) and epigenetic (hTERT promoter methylation and miRNAs) events were shown to have clinical implications in cancers that depend on hTERT activation. Knowing that telomeres are crucial for cellular self-renewal, the mechanisms responsible for telomere maintenance have a crucial role in cancer diseases and might be important oncological biomarkers. Thus, rather than quantifying TERT expression and its correlation with telomerase activation, the discovery and the assessment of the mechanisms responsible for TERT upregulation offers important information that may be used for diagnosis, prognosis, and treatment monitoring in oncology. Furthermore, a better understanding of these mechanisms may promote their translation into effective targeted cancer therapies. Conclusion Herein, we reviewed the underlying mechanisms of hTERT regulation, their role in oncogenesis, and the potential clinical applications in telomerase-dependent cancers.info:eu-repo/semantics/publishedVersio

    Socio economic upliftment of tribal community through adoption of climate resilient technologies under TSP programme at Jalakiasuti village of Dhemaji districtof Assam

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    Not AvailableSocio economic upliftment of tribal community through adoption of climate resilient technologies under TSP programme at Jalakiasuti village of Dhemaji districtof AssamNot Availabl

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    Not AvailableComparative evaluation of different farming system models suitable for small and marginal farmers of NagalandNot Availabl

    Building climate resilient agriculture through traditional floating rice in flash flood affected areas of the North bank plains zone of Assam

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    632-638Flash floods are a recurrent phenomenon in the North Bank Plains Zone (NBPZ) of Assam, India, causing wide spread damage to rice (Oryza sativa L.) crop growing during Kharif season. Therefore, it is imperative to identify indigenous technical knowledge and integrate this with mainstream technologies, Maguri and not only to enable more effective ways of coping with such extreme events but also to enhance the adaptive capacity of small-scale local farmers of the NBPZ. Identifying and evaluating traditional crop varieties in the NBPZ that are flood tolerant is one approach that may help manage weather hazards and build climate resilient agricultural systems. This research represents investigations on more flood-resistant local rice varieties. In 2013 and 2014, participatory on-farm trials were conducted in Ganakdolonivillage, a community in NBPZ affected by flash floods. Thirty sites covering 20 ha were selected to evaluate the performance of five traditional floating rice (bao)varieties: Kekua, Tulshi, Dhushuri, Bahadur Rangabao. In both the years, the rice fields were affected by flooding multiple times, to a depth of up to 173 cm. The rice varieties recommended for normal, submergence and deep water situations could not perform well and were damaged extensively. The traditional rice varieties generally growing in deep water situations, however, endured the flash floods, performing better and producing grain yields from 1628 to 3000 kg ha-1. Amongst these traditional varieties, Dhushuri recorded the highest grain yield in both the years

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    Not AvailableComparative evaluation of different farming system models suitable for small and marginal farmers of NagalandNot Availabl

    Resiliant Agriculture for flash flood affected areas of north bank plains zone of Assam

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    Not AvailableResiliant Agriculture for flash flood affected areas of north bank plains zone of AssamNot Availabl
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