Fish and freshwater crayfish in streams in the Cape Naturaliste region and Wilyabrup Brook

No abstract availabl

Theology at the coal-face of hospitalisation - the development and evaluation of a postgraduate certificate in Healthcare Chaplaincy

Healthcare chaplaincy is working towards recognition as a registered health profession. An accredited programme of professional education is part of that process. The University of Glasgow supported by NHS Education for Scotland have developed a programme of professional education for healthcare chaplains that is integrated into an MSc. (MedSci) in healthcare. This article outlines the commissioning, development and evaluation of a postgraduate certificate in healthcare chaplaincy by students, clinical mentors and experienced healthcare chaplains. It also highlights an innovative approach to practice development in spiritual and religious care in healthcare

Bacterial Quality of Private Water Wells in Clark County, Arkansas

Most private water wells in Clark County appeared to be contaminated by bacteria, apparently entering the wells from surface water seepage. Eighteen to 24% of the wells investigated were positive for fecal contamination. Deeper wells were less often contaminated. More than one-half of the wells sampled exceeded recommended limits of inorganic chemicals for safe potable water. High concentrations of iron and manganese were most common, exceeding recommended limits in more than 40% of the well

Spatial variation of iron abundance in the high speed solar wind, 1972 to 1976

The Fe/H ratios in the peaks of high speed streams (HSS) during the decline of Solar Cycle 20 and the following minimum (October 1972-December 1976) were analyzed. The response of the 50-200 keV ion channel of the APL/JHU energetic particle experiment (EPE) on IMP-7 and 8 to solar wind iron ions at high solar wind speeds and Fe measurements were compared with solar wind H and He parameters from the Los Alamos National Laboratory (LANL) instruments on the same spacecraft. In general, the Fe distribution parameters (bulk velocity, flow direction, temperature) are found to be similar to the LANL He parameters. Although the average Fe/H ratio in many steady HSS peaks agrees within observational uncertainties with the nominal coronal ratio of 4.7 x 10(-5), abundance variations of a factor of up to 6 are obtained across a given coronal-hole associated HSS. Over the period 1973-1976, a steady decrease in the average quiet-time Fe/H ratio by a factor of about 4 is measured on both IMP-7 and 8

Hypothesis testing near singularities and boundaries

The likelihood ratio statistic, with its asymptotic $\chi^2$ distribution at regular model points, is often used for hypothesis testing. At model singularities and boundaries, however, the asymptotic distribution may not be $\chi^2$, as highlighted by recent work of Drton. Indeed, poor behavior of a $\chi^2$ for testing near singularities and boundaries is apparent in simulations, and can lead to conservative or anti-conservative tests. Here we develop a new distribution designed for use in hypothesis testing near singularities and boundaries, which asymptotically agrees with that of the likelihood ratio statistic. For two example trinomial models, arising in the context of inference of evolutionary trees, we show the new distributions outperform a $\chi^2$.Comment: 32 pages, 12 figure

Argon protects against hypoxic-ischemic brain injury in neonatal rats through activation of Nuclear factor (erythroid-derived 2)-like 2

Perinatal hypoxic ischaemic encephalopathy (HIE) has a high mortality rate with neuropsychological impairment. This study investigated the neuroprotective effects of argon against neonatal hypoxic-ischaemic brain injury. In vitro cortical neuronal cell cultures derived from rat foetuses were subjected to an oxygen and glucose deprivation (OGD) challenge for 90 minutes and then exposed to 70% argon or nitrogen with 5% carbon dioxide and balanced with oxygen for 2 hours. In vivo, seven-day-old rats were subjected to unilateral common carotid artery ligation followed by hypoxic (8% oxygen balanced with nitrogen) insult for 90 minutes. They were exposed to 70% argon or nitrogen balanced with oxygen for 2 hours. In vitro, argon treatment of cortical neuronal cultures resulted in a significant increase of p-mTOR and Nuclear factor (erythroid-derived 2)-like 2(Nrf2) and protection against OGD challenge. Inhibition of m-TOR through Rapamycin or Nrf2 through siRNA abolished argon-mediated cyto-protection. In vivo, argon exposure significantly enhanced Nrf2 and its down-stream effector NAD(P)H Dehydrogenase, Quinone 1(NQO1) and superoxide dismutase 1(SOD1). Oxidative stress, neuroinflammation and neuronal cell death were significantly decreased and brain infarction was markedly reduced. Blocking PI-3K through wortmannin or ERK1/2 through U0126 attenuated argon-mediated neuroprotection. These data provide a new molecular mechanism for the potential application of Argon as a neuroprotectant in HIE

Perceived characteristics of the environment associated with active travel: development and testing of a new scale

Background Environmental characteristics may be associated with patterns of physical activity. However, the development of instruments to measure perceived characteristics of the local environment is still at a comparatively early stage, and published instruments are not necessarily suitable for application in all settings. We therefore developed and established the test-retest reliability of a new scale for use in a study of the correlates of active travel and overall physical activity in deprived urban neighbourhoods in Glasgow, Scotland. Methods We developed and piloted a 14-item scale based on seven constructs identified from the literature (aesthetics, green space, access to amenities, convenience of routes, traffic, road safety and personal safety). We administered the scale to all participants in a random postal survey (n = 1322) and readministered the scale to a subset of original respondents (n = 125) six months later. We used principal components analysis and Varimax rotation to identify three principal components (factors) and derived summary scores for subscales based on these factors. We examined the internal consistency of these subscales using Cronbach's alpha and examined the test-retest reliability of the individual items, the subscale summary scores and an overall summary neighbourhood score using a combination of correlation coefficients and Cohen's kappa with and without weighting. Results Public transport and proximity to shops were the items most likely to be rated positively, whereas traffic volume, traffic noise and road safety for cyclists were most likely to be rated negatively. Three principal components – 'safe and pleasant surroundings', 'low traffic' and 'convenience for walking' – together explained 45% of the total variance. The test-retest reliability of individual items was comparable with that of items in other published scales (intraclass correlation coefficients (ICCs) 0.34–0.70; weighted Cohen's kappa 0.24–0.59). The overall summary neighbourhood score had acceptable internal consistency (Cronbach's alpha 0.72) and test-retest reliability (ICC 0.73). Conclusion This new scale contributes to the development of a growing set of tools for investigating the role of perceived environmental characteristics in explaining or mediating patterns of active travel and physical activity

Quantum Algorithm to Solve Satisfiability Problems

A new quantum algorithm is proposed to solve Satisfiability(SAT) problems by taking advantage of non-unitary transformation in ground state quantum computer. The energy gap scale of the ground state quantum computer is analyzed for 3-bit Exact Cover problems. The time cost of this algorithm on general SAT problems is discussed.Comment: 5 pages, 3 figure