24 research outputs found

    Developmental gene networks: a triathlon on the course to T cell identity

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    Atypical chorioretinal coloboma in a Golden Retriever: a retinographic, fluoroangiographic, and optical coherence tomography study

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    Purpose: To report a case of canine atypical chorioretinal coloboma where ophthalmoscopic, fluoroangiographic and optical coherence tomography characteristics are described. Animal Studied: A 2-year-old Golden Retriever dog in which routine ophthalmoscopic examination allowed diagnosis of a posterior coloboma on the left eye. Procedures: Retinography, fluorescein angiography, and optical coherence tomography were performed to characterize the lesion of the left fundus. Results: Ophthalmoscopy revealed a pigmented circumscribed lesion dorsal to the optic nerve of the left fundus, surrounded by small areas of hyper-reflectivity and retinal vessels with an abnormal pattern. Fluoroangiography revealed a constant hypofluorescence of the defect and a complete altered vascular pattern associated with the coloboma. Optical coherence study demonstrated an important craterlike depression showing an atrophic neurosensory retina, and a lack of retinal pigment epithelium and choroidal tissue. Conclusions: Fluoroangiographic and optical coherence tomographic studies of an atypical chorioretinal coloboma in a dog are reported for the first time. Both imaging techniques are of great importance to characterize this type of congenital defects.Depto. de Medicina y CirugĂ­a AnimalFac. de VeterinariaTRUEpu
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