Vanishing Next-to-Leading Corrections to the \beta-Function of the SUSY CP^{N-1} Model in Three Dimensions

We study the ultraviolet properties of the supersymmetric CP^{N-1} sigma model in three dimensions to next-to-leading order in the 1/N expansion. We calculate the \beta-function to this order and verify that it has no next-to-leading order corrections.Comment: 8 pages, 1 figure, the renormalization constant of the field alpha is correcte

Japan and the CGIAR: Strengthening the Partnership

Partnership book on CGIAR and Japan, written by Masayoshi Saito during his assignment at the CGIAR Secretariat in June 2006

The Diagnosis and Treatment of Early-Stage Colorectal Cancer

The introduction of colorectal endoscopic submucosal dissection (ESD) has expanded the applications for endoscopic treatment; as a result, lesions with low metastatic potential can be treated endoscopically regardless of the lesion size. The most attractive feature of ESD is the achievement of en bloc resection with a lower local recurrence rate in comparison to that of endoscopic piecemeal mucosal resection. However, in case of gastric cancers, ESD is not as widely applied to the treatment of colorectal neoplasms because of its technical difficulty, longer procedural time, and increased perforation risk. In the movement toward diversified endoscopic treatment strategies for superficial colorectal neoplasms, endoscopists who begin to perform ESD need to recognize the indications of ESD, as well as the technical issues and associated complications of this procedure

Cancellation of UV Divergences in the N=4 SUSY Nonlinear Sigma Model in Three Dimensions

We study the UV properties of the three-dimensional ${\cal N}=4$ SUSY nonlinear sigma model whose target space is $T^*(CP^{N-1})$ (the cotangent bundle of $CP^{N-1}$) to higher orders in the 1/N expansion. We calculate the $\beta$-function to next-to-leading order and verify that it has no quantum corrections at leading and next-to-leading orders.Comment: 10 pages, 2 figures. references adde

RNA-seq Transcriptional Profiling of an Arbuscular Mycorrhiza Provides Insights into Regulated and Coordinated Gene Expression in Lotus japonicus and Rhizophagus irregularis

Gene expression during arbuscular mycorrhizal development is highly orchestrated in both plants and arbuscular mycorrhizal fungi. To elucidate the gene expression profiles of the symbiotic association, we performed a digital gene expression analysis of Lotus japonicus and Rhizophagus irregularis using a HiSeq 2000 next-generation sequencer with a Cufflinks assembly and de novo transcriptome assembly. There were 3,641 genes differentially expressed during arbuscular mycorrhizal development in L. japonicus, approximately 80% of which were up-regulated. The up-regulated genes included secreted proteins, transporters, proteins involved in lipid and amino acid metabolism, ribosomes and histones. We also detected many genes that were differentially expressed in small-secreted peptides and transcription factors, which may be involved in signal transduction or transcription regulation during symbiosis. Coregulated genes between arbuscular mycorrhizal and root nodule symbiosis were not particularly abundant, but transcripts encoding for membrane traffic-related proteins, transporters and iron transport-related proteins were found to be highly co-up-regulated. In transcripts of arbuscular mycorrhizal fungi, expansion of cytochrome P450 was observed, which may contribute to various metabolic pathways required to accommodate roots and soil. The comprehensive gene expression data of both plants and arbuscular mycorrhizal fungi provide a powerful platform for investigating the functional and molecular mechanisms underlying arbuscular mycorrhizal symbiosis.ArticlePLANT AND CELL PHYSIOLOGY. 56(8):1490-1511 (2015)journal articl

Effects of Eating or Skipping Breakfast on Heart Rate and Oxygen Uptake

The purpose of this study was to compare changes in heart rate, oxygen uptake, blood pressure and oral temperature between subjects eating breakfast and subjects skipping breakfast when they exercise each day at 11:00 AM and 2:00 PM. The study design included two different groups, a breakfast group and a skipping group. Subjects rested for five minutes, and they exercised on a pendulum ergometer for twenty minutes. After exercising, the resistance was returned to zero for a one minute cool down followed by five more minutes of complete rest(recovery phase). Oral temperatures of the skipping group were lower than those of the breakfast group at 11:00 AM. Diet induced thermogenesis (DIT), which increases core body temperature, is generated by eating breakfast. In the skipping group, the resting heart rates at 11:00 AM were lower than at 2:00 PM. A significant difference in heart rate after the first minute of exercise was seen between 11:00 AM and 2:00 PM in the skipping group. These results suggested that when skipping breakfast, the heart rate response immediately after beginning exercise is slow in the morning. Although all subjects did cooling down for one minute after exercising, oxygen uptake during the recovery phase in the skipping group at 11:00 AM was significantly higher than at rest. These results suggest that eating breakfast has a physiological influence on both heart rate and oxygen uptake

Japan College of Rheumatology 2009 guidelines for the use of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, in rheumatoid arthritis

The introduction of biological agents targeting tumor necrosis factor-alpha (TNF-α) has brought about a paradigm shift in the treatment of rheumatoid arthritis (RA). Although these anti-TNF agents have excellent efficacy against RA, a substantial number of patients still show inadequate responses. In Western countries, such patients are already being treated with new classes of antirheumatic drugs such as abatacept and rituximab. Tocilizumab (TCZ) is a humanized monoclonal antibody developed in Japan against the human interleukin-6 (IL-6) receptor. TCZ does not only alleviate the signs and symptoms of RA but also seems to prevent progressive bone and joint destruction. However, there is a concern that TCZ might increase the risk of adverse events such as infections since IL-6 plays a pivotal role in the immune system. Calculating the relative risks of specific adverse outcomes with TCZ use remains difficult, due to insufficient patient numbers enrolled in clinical trials to date. This review presents tentative guidelines for the use of TCZ for RA patients prepared by the Japan College of Rheumatology and based on results of clinical trials in Japan and Western countries. The guidelines are intended as a guide for postmarketing surveillance and clinical practice, and will be revised periodically based on the surveillance

Anatomical variation of the Psoas Valley: a scoping review

Abstract: Background: This scoping review aimed to investigate the literature on the anatomy of the psoas valley, an anterior depression on the acetabular rim, and propose a unified definition of the anatomical structure, describe its dimensions, anatomical variations and clinical implications. Methods: A systematic computer search of EMBASE, PubMed and Cochrane for literature related to the psoas valley was undertaken using Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. Clinical outcome studies, prospective/retrospective case series, case reports and review articles that described the psoas valley and its synonyms were included. Studies on animals as well as book chapters were excluded. Results: Of the 313 articles, the filtered literature search identified 14 papers describing the psoas valley and its synonyms such as iliopsoas notch, a notch between anterior inferior iliac spine and the iliopubic eminence, Psoas-U and anterior wall depression. Most of these were cross-sectional studies that mainly analyzed normal skeletal hips. In terms of anatomical variation, 4 different configurations of the anterior acetabular rim have been identified and it was found that the curved type was the most frequent while the straight type may be nonexistent. Additionally, the psoas valley tended to be deeper in males as compared with females. Several papers established the psoas valley, or Psoas-U in a consistent location at approximately 3 o’clock on the acetabular rim which may have implications with labral pathology. Conclusion: This review highlights the importance of the anatomy of the psoas valley which is a consistent bony landmark. The anatomy and the anatomical variations of the psoas valley need to be well-appreciated by surgeons involved in the management of young adults with hip pathology and also joint replacement surgeons to ensure appropriate seating of the acetabular component

Atypical Symptoms in Migraine-Related Alice in Wonderland Syndrome: Expansion of the Phenotype and Reflection on the Pathomechanism

We report an 8-year-old girl who experienced daily episodes of visual and somesthetic distortion and was diagnosed with Alice in wonderland syndrome (AIWS). Ophthalmologic assessment revealed best-corrected visual acuity of 0.2 in both eyes, and bilateral constricted tubular or spiral visual fields. Augmented amplitude of visually evoked potentials was revealed, and treatment with lomerizine and valproate showed favorable effect on the visual/somesthetic distortion as well as the visual field and acuity. Psychogenic visual problems can co-exist with the typical sensory distortion in AIWS, similarly to the case of psychogenic pseudo-seizures in subjects with epilepsy. Otherwise, an ambiguous borderline between psychological and physical pathomechanisms in migraine may also be characteristic of the migraine-related AIWS