333 research outputs found
Altered expression of Alzheimer's disease-related proteins in male hypogonadal mice
Age-related depletion of estrogens and androgens is associated with an increase in Alzheimer's disease (AD) brain pathology and diminished cognitive function. Here we investigated AD-associated molecular and cellular changes in brains of aged hypogonadal (hpg) male and female mice. hpg Mice have a spontaneous, inactivating genetic mutation in the GnRH gene resulting in lifelong deficiency of gonadotropins and gonadal sex hormones. Western blot analysis revealed low levels of amyloid precursor protein and high levels of presenilin 1, amyloid precursor protein C-terminal fragment, and beta-amyloid 42 in brains of aged male, but not female, hpg mice. Changes were confined to the hippocampus and were not evident in the cerebellum or other brain tissues. Male hpg mice tended to have lower levels of IL-1 beta protein than male littermate controls. Immunohistochemical staining of the basal forebrain revealed that male hpg mice had lower choline acetyltransferase levels per neuron compared with controls. These AD-like changes specific to male hpg mice supports a link between androgen depletion and the development of AD pathology
Particle size distribution and mineralogy of Brazilian Ferralsols: Significance for the structure and hydraulic properties.
The Cerrados Biome is one of the major regions of Brazil with 24% of the Brazilian territory (204.106 ha). It is mainly located in the center of Brazil and corresponds to the whole Central Plateau. About 49% of the soils are Ferralsols and approximately 79.106 ha of these soils are dedicated to agriculture. The main characteristics of Ferralsols are a poor horizonation, a weak development of the macrostructure, and a strong submillimetric granular microstructure
Medium-chain triglyceride supplementation may increase working memory in older adults: A pilot study
Poster presentatio
List Of Angiosperm Species In An Atlantic Forest Fragment Reveals Collection Gaps In Espírito Santo State, Brazil
This study presents a list of angiosperm species in an Atlantic Forest fragment in the southern portion of Espírito Santo state, Brazil, a region that represents a collection gap within the Atlantic Forest. The studied site is a relatively small fragment of 144 ha located within a conservation unit, the Mata das Flores State Park. The site belongs to a conservation priority area for the Atlantic Forest in Espírito Santo, and is under strong anthropic pressure. Of the 239 species listed here, 21 are new records for the state, eight are endemic, and 20 figure either in the country’s or the state’s Red Lists of endangered species. Rubiaceae and Piperaceae were the families with the highest number of species. We show that small fragments that were never inventoried before can reveal a relatively large number of threatened species and that collection gaps need to be filled in order to refine our understanding about conservation priorities within the Atlantic Forest Biome. © 2016 Check List and Authors.12111
BB Intermeson Potentials in the Quark Model
In this paper we derive quark model results for scattering amplitudes and
equivalent low energy potentials for heavy meson pairs, in which each meson
contains a heavy quark. This "BB" system is an attractive theoretical
laboratory for the study of the nuclear force between color singlets; the
hadronic system is relatively simple, and there are lattice gauge theory (LGT)
results for V_BB(r) which may be compared to phenomenological models. We find
that the quark model potential (after lattice smearing) has qualitative
similarities to the LGT potential in the two B*B* channels in which direct
comparison is possible, although there is evidence of a difference in length
scales. The quark model prediction of equal magnitude but opposite sign for I=0
and I=1 potentials also appears similar to LGT results at intermediate r. There
may however be a discrepancy between the LGT and quark model I=1 BB potentials.
A numerical study of the two-meson Schrodinger equations in the (bqbar)(bqbar)
and (cqbar)(cqbar) sectors with the quark model potentials finds a single
"molecule", in the I=0 BB* sector. Binding in other channels might occur if the
quark model forces are augmented by pion exchange.Comment: 30 pages, 5 figures, revtex and epsfig. Submitted to Phys. Rev.
Spin- and charge-density oscillations in spin chains and quantum wires
We analyze the spin- and charge-density oscillations near impurities in spin
chains and quantum wires. These so-called Friedel oscillations give detailed
information about the impurity and also about the interactions in the system.
The temperature dependence of these oscillations explicitly shows the
renormalization of backscattering and conductivity, which we analyze for a
number of different impurity models. We are also able to analyze screening
effects in one dimension. The relation to the Kondo effect and experimental
consequences are discussed.Comment: Final published version. 15 pages in revtex format including 22
epsf-embedded figures. The latest version in PDF format is available from
http://fy.chalmers.se/~eggert/papers/density-osc.pd
Series study of the One-dimensional S-T Spin-Orbital Model
We use perturbative series expansions about a staggered dimerized ground
state to compute the ground state energy, triplet excitation spectra and
spectral weight for a one-dimensional model in which each site has an S=\case
1/2 spin and a pseudospin , representing a doubly
degenerate orbital. An explicit dimerization is introduced to allow study of
the confinement of spinon excitations. The elementary triplet represents a
bound state of two spinons, and is stable over much of the Brillouine zone. A
special line is found in the gapped spin-liquid phase, on which the triplet
excitation is dispersionless. The formation of triplet bound states is also
investigated.Comment: 9 pages, 9 figure
Dissociation cross sections of ground-state and excited charmonia with light mesons in the quark model
We present numerical results for the dissociation cross sections of
ground-state, orbitally- and radially-excited charmonia in collisions with
light mesons. Our results are derived using the nonrelativistic quark model, so
all parameters are determined by fits to the experimental meson spectrum.
Examples of dissociation into both exclusive and inclusive final states are
considered. The dissociation cross sections of several C=(+) charmonia may be
of considerable importance for the study of heavy ion collisions, since these
states are expected to be produced more copiously than the J/psi. The relative
importance of the productions of ground-state and orbitally-excited charmed
mesons in a pion-charmonium collision is demonstrated through the -dependent charmonium dissociation cross sections.Comment: 9 pages, 8 figure
Constraints on the CMB temperature redshift dependence from SZ and distance measurements
The relation between redshift and the CMB temperature,
is a key prediction of standard cosmology, but is violated in many non-standard
models. Constraining possible deviations to this law is an effective way to
test the CDM paradigm and search for hints of new physics. We present
state-of-the-art constraints, using both direct and indirect measurements. In
particular, we point out that in models where photons can be created or
destroyed, not only does the temperature-redshift relation change, but so does
the distance duality relation, and these departures from the standard behaviour
are related, providing us with an opportunity to improve constraints. We show
that current datasets limit possible deviations of the form
to be up to a redshift
. We also discuss how, with the next generation of space and
ground-based experiments, these constraints can be improved by more than one
order of magnitude.Comment: 27 pages, 11 figure
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