Fatty acids composition and age estimation of wild Octopus vulgaris paralarvae

Under culture conditions, lipid composition and specifically, the fatty acid profile of reared paralarvae is significantly different from hatchlings. Therefore, comparing wild paralarvae and reared paralarvae of similar age would allow us to elucidate if the changes in fatty acid profile are related with a non-optimal prey composition or are caused by the normal development. The aim of this study was analyze, for the very first time, the fatty acid profile of wild Octopus vulgaris paralarvae individually, determining for each paralarvae their age through deposition of daily increments on lateral hood surface of the beaks. The main goal is to clear up lipid requirements of paralarvae and optimise the diet of reared paralarvae

Fatty acid composition and age estimation of wild Octopus vulgaris paralarvae

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ESTIMACIÓN DE LA EDAD Y DETERMINACIÓN DEL PERFIL DE ÁCIDOS GRASOS EN PARALARVAS SALVAJES DE PULPO COMÚN (Octopus vulgaris)

Bajo condiciones de cultivo, la composición lipídica y, específicamente, el perfil de ácidos grasos de las paralarvas cultivadas, es significativamente diferente al de las paralarvas recién eclosionadas. Por tanto, la comparación entre paralarvas salvajes y cultivadas de edad equivalente, permitiría dilucidar si estos cambios detectados en el perfil de ácidos grasos están relacionados con una dieta inadecuada o son causados por el propio desarrollo de la paralarva. En el presente estudio, se analizó por primera vez de forma individual el perfil de ácidos grasos de paralarvas salvajes de Octopus vulgaris y se determinó su edad a través de la deposición diaria de los incrementos en los picos, con el objetivo de profundizar en los requerimientos lipídicos de las paralarvas a lo largo del desarrollo y de esta forma intentar optimizar la dieta de los ejemplares en cultivo

RICORS2040 : The need for collaborative research in chronic kidney disease

Chronic kidney disease (CKD) is a silent and poorly known killer. The current concept of CKD is relatively young and uptake by the public, physicians and health authorities is not widespread. Physicians still confuse CKD with chronic kidney insufficiency or failure. For the wider public and health authorities, CKD evokes kidney replacement therapy (KRT). In Spain, the prevalence of KRT is 0.13%. Thus health authorities may consider CKD a non-issue: very few persons eventually need KRT and, for those in whom kidneys fail, the problem is 'solved' by dialysis or kidney transplantation. However, KRT is the tip of the iceberg in the burden of CKD. The main burden of CKD is accelerated ageing and premature death. The cut-off points for kidney function and kidney damage indexes that define CKD also mark an increased risk for all-cause premature death. CKD is the most prevalent risk factor for lethal coronavirus disease 2019 (COVID-19) and the factor that most increases the risk of death in COVID-19, after old age. Men and women undergoing KRT still have an annual mortality that is 10- to 100-fold higher than similar-age peers, and life expectancy is shortened by ~40 years for young persons on dialysis and by 15 years for young persons with a functioning kidney graft. CKD is expected to become the fifth greatest global cause of death by 2040 and the second greatest cause of death in Spain before the end of the century, a time when one in four Spaniards will have CKD. However, by 2022, CKD will become the only top-15 global predicted cause of death that is not supported by a dedicated well-funded Centres for Biomedical Research (CIBER) network structure in Spain. Realizing the underestimation of the CKD burden of disease by health authorities, the Decade of the Kidney initiative for 2020-2030 was launched by the American Association of Kidney Patients and the European Kidney Health Alliance. Leading Spanish kidney researchers grouped in the kidney collaborative research network Red de Investigación Renal have now applied for the Redes de Investigación Cooperativa Orientadas a Resultados en Salud (RICORS) call for collaborative research in Spain with the support of the Spanish Society of Nephrology, Federación Nacional de Asociaciones para la Lucha Contra las Enfermedades del Riñón and ONT: RICORS2040 aims to prevent the dire predictions for the global 2040 burden of CKD from becoming true