628 research outputs found
Targeting biotypes of Dactylopius tomentosus to improve effective biocontrol of Cylindropuntia spp. in Australia
Seven Dactylopius tomentosus (Lamarck) biotypes were collected from a range of Cylindropuntia spp. in Mexico, South Africa and United States of America (USA) and imported into quarantine facilities at the Ecosciences Precinct. Host range trials were conducted for each biotype and further assessed against the Cylindropuntia species that are naturalised in Australia to determine the most effective biotype for each species. Host range was confined to the Cylindropuntia for all seven biotypes. In the efficacy trials, C. imbricata (Haw.) F.M.Knuth was killed by the ‘imbricata’ biotype within 16 weeks and C. kleiniae (DC.) F.M.Knuth died within 26 weeks. Cylindropuntia
fulgida var. mamillata (DC.) Backeb. and C. imbricata were killed by the ‘fulgida’ biotype within 18 weeks. On-going trials suggest that C. rosea (DC.) Backeb. could be controlled by either the ‘acanthocarpa’ or the ‘acanthocarpa × echinocarpa’ biotypes. Cylindropuntia
spinosior (Englem.) F.M.Knuth was not susceptible to any of the D. tomentosus biotypes assessed. A clear designation of which D. tomentosus biotype is most suited for each Cylindropuntia species will improve and increase the effectiveness of biological control of these weed specie
Targeting biotypes of Dactylopius tomentosus to improve effective biocontrol of Cylindropuntia spp. in Australia
Seven Dactylopius tomentosus (Lamarck) biotypes were collected from a range of Cylindropuntia spp. in Mexico, South Africa and United States of America (USA) and imported into quarantine facilities at the Ecosciences Precinct. Host range trials were conducted for each biotype and further assessed against the Cylindropuntia species that are naturalised in Australia to determine the most effective biotype for each species. Host range was confined to the Cylindropuntia for all seven biotypes. In the efficacy trials, C. imbricata (Haw.) F.M.Knuth was killed by the ‘imbricata’ biotype within 16 weeks and C. kleiniae (DC.) F.M.Knuth died within 26 weeks. Cylindropuntia
fulgida var. mamillata (DC.) Backeb. and C. imbricata were killed by the ‘fulgida’ biotype within 18 weeks. On-going trials suggest that C. rosea (DC.) Backeb. could be controlled by either the ‘acanthocarpa’ or the ‘acanthocarpa × echinocarpa’ biotypes. Cylindropuntia
spinosior (Englem.) F.M.Knuth was not susceptible to any of the D. tomentosus biotypes assessed. A clear designation of which D. tomentosus biotype is most suited for each Cylindropuntia species will improve and increase the effectiveness of biological control of these weed specie
Silicon isotopes reveal recycled altered oceanic crust in the mantle sources of ocean island basalts
EP thanks the Chateaubriand STEM fellowship program for funding. FM thanks the European Research Council under the European Community’s H2020 framework program/ERC grant agreement #637503 (Pristine) and the Agence Nationale de la Recherche for a chaire d’Excellence Sorbonne Paris Cité (IDEX13C445) and for the UnivEarthS Labex program (ANR-10-LABX-0023 and ANR-11-IDEX-0005-02). PS thanks the support of the Marie Curie FP7-IOF fellowship “Isovolc”.The study of silicon (Si) isotopes in Ocean Island Basalts (OIB) has the potential to discern between different models for the origins of geochemical heterogeneities in the mantle. Relatively large (∼several per mil per atomic mass unit) Si isotope fractionation occurs in low-temperature environments during biochemical and geochemical precipitation of dissolved Si, where the precipitate is preferentially enriched in the lighter isotopes relative to the dissolved Si. In contrast, only a limited range (∼tenths of a per mil) of Si isotope fractionation has been observed from high-temperature igneous processes. Therefore, Si isotopes may be useful as tracers for the presence of crustal material within OIB mantle source regions that experienced relatively low-temperature surface processes in a manner similar to other stable isotope systems, such as oxygen. Characterizing the isotopic composition of the mantle is also of central importance to the use of the Si isotope system as a basis for comparisons with other planetary bodies (e.g., Moon, Mars, asteroids). Here we present the first comprehensive suite of high-precision Si isotope data obtained by MC-ICP-MS for a diverse suite of OIB. Samples originate from ocean islands in the Pacific, Atlantic, and Indian Ocean basins and include representative end-members for the EM-1, EM-2, and HIMU mantle components. On average, δ30Si values for OIB (−0.32 ± 0.09‰, 2 sd) are in general agreement with previous estimates for the δ30Si value of Bulk Silicate Earth (−0.29 ± 0.07‰, 2 sd; Savage et al., 2014). Nonetheless, some small systematic variations are present; specifically, most HIMU-type (Mangaia; Cape Verde; La Palma, Canary Islands) and Iceland OIB are enriched in the lighter isotopes of Si (δ30Si values lower than MORB), consistent with recycled altered oceanic crust and lithospheric mantle in their mantle sources.PostprintPeer reviewe
Plus ça change : pots, crucibles and the development of metallurgy in Chalcolithic Las Pilas (Mojácar, Spain)
This paper considers the structure of production, distribution and consumption of ceramics within Chalcolithic communities of SE Iberia, an important region for modelling social and technological change in the recent prehistory of Eurasia. Our research provides new data through the comparative analysis of domestic and metallurgical ceramics, as well as building and other clay-rich materials from the archaeological site of Las Pilas (2875–2620 cal. BC 2σ to 2460–2205 cal. BC 2σ) (Mojácar, Almería). In total, 56 samples are characterised by optical petrography, with SEM analysis of 22 of those individuals, in order to assess firing conditions. Results point to the existence of a local tradition in which domestic and metallurgical wares exhibit important similarities in their production processes. In terms of technology, the assemblage shows a relative homogeneity, although firing conditions, surface treatment and decoration seem to have played an important role in the differentiation of highly symbolic wares from other ceramics. We conclude that raw material procurement and processing at Las Pilas differ from those at other Copper Age sites already studied in SE and SW Iberia. This is in agreement with earlier archaeometallurgical studies on Las Pilas, suggesting the development of local and community-based technological traditions. As such, the paper attempts to bridge the recent divide between re-emergent top-down models and our detailed understandings of technological practice
Channel diffusion of sodium in a silicate glass
We use classical molecular dynamics simulations to study the dynamics of
sodium atoms in amorphous NaO-4SiO. We find that the sodium
trajectories form a well connected network of pockets and channels. Inside
these channels the motion of the atoms is not cooperative but rather given by
independent thermally activated hops of individual atoms between the pockets.
By determining the probability that an atom returns to a given starting site,
we show that such events are not important for the dynamics of this system.Comment: 10 pages of Latex, 5 figures, one figure added, text expande
Exoskeletal predator defenses of juvenile California spiny lobsters (Panulirus interruptus) are affected by fluctuating ocean acidification-like conditions
Spiny lobsters rely on multiple biomineralized exoskeletal predator defenses that may be sensitive to ocean acidification (OA). Compromised mechanical integrity of these defensive structures may tilt predator-prey outcomes, leading to increased mortality in the lobsters’ environment. Here, we tested the effects of OA-like conditions on the mechanical integrity of selected exoskeletal defenses of juvenile California spiny lobster, Panulirus interruptus. Young spiny lobsters reside in kelp forests with dynamic carbonate chemistry due to local metabolism and photosynthesis as well as seasonal upwelling, yielding daily and seasonal fluctuations in pH. Lobsters were exposed to a series of stable and diurnally fluctuating reduced pH conditions for three months (ambient pH/stable, 7.97; reduced pH/stable 7.67; reduced pH with low fluctuations, 7.67 ± 0.05; reduced pH with high fluctuations, 7.67 ± 0.10), after which we examined the intermolt composition (Ca and Mg content), ultrastructure (cuticle and layer thickness), and mechanical properties (hardness and stiffness) of selected exoskeletal predator defenses. Cuticle ultrastructure was consistently robust to pH conditions, while mineralization and mechanical properties were variable. Notably, the carapace was less mineralized under both reduced pH treatments with fluctuations, but with no effect on material properties, and the rostral horn had lower hardness in reduced/high fluctuating conditions without a corresponding difference in mineralization. Antennal flexural stiffness was lower in reduced, stable pH conditions compared to the reduced pH treatment with high fluctuations and not correlated with changes in cuticle structure or mineralization. These results demonstrate a complex relationship between mineralization and mechanical properties of the exoskeleton under changing ocean chemistry, and that fluctuating reduced pH conditions can induce responses not observed under the stable reduced pH conditions often used in OA research. Furthermore, this study shows that some juvenile California spiny lobster exoskeletal defenses are responsive to changes in ocean carbonate chemistry, even during the intermolt period, in ways that can potentially increase susceptibility to predation among this critical life stage
Integration of genetics into a systems model of electrocardiographic traits using humanCVD BeadChip
<p>Background—Electrocardiographic traits are important, substantially heritable determinants of risk of arrhythmias and sudden cardiac death.</p>
<p>Methods and Results—In this study, 3 population-based cohorts (n=10 526) genotyped with the Illumina HumanCVD Beadchip and 4 quantitative electrocardiographic traits (PR interval, QRS axis, QRS duration, and QTc interval) were evaluated for single-nucleotide polymorphism associations. Six gene regions contained single nucleotide polymorphisms associated with these traits at P<10−6, including SCN5A (PR interval and QRS duration), CAV1-CAV2 locus (PR interval), CDKN1A (QRS duration), NOS1AP, KCNH2, and KCNQ1 (QTc interval). Expression quantitative trait loci analyses of top associated single-nucleotide polymorphisms were undertaken in human heart and aortic tissues. NOS1AP, SCN5A, IGFBP3, CYP2C9, and CAV1 showed evidence of differential allelic expression. We modeled the effects of ion channel activity on electrocardiographic parameters, estimating the change in gene expression that would account for our observed associations, thus relating epidemiological observations and expression quantitative trait loci data to a systems model of the ECG.</p>
<p>Conclusions—These association results replicate and refine the mapping of previous genome-wide association study findings for electrocardiographic traits, while the expression analysis and modeling approaches offer supporting evidence for a functional role of some of these loci in cardiac excitation/conduction.</p>
GS-2: A novel Broad-Spectrum agent for environmental microbial control
The environmental control of microbial pathogens currently relies on compounds that do not exert long-lasting activity on surfaces, are impaired by soil, and contribute to the growing problem of antimicrobial resistance. This study presents the scientific development and characterization of GS-2, a novel, water-soluble ammonium carboxylate salt of capric acid and L-arginine that demonstrates activity against a range of bacteria (particularly Gram-negative bacteria), fungi, and viruses. In real-world surface testing, GS-2 was more effective than a benzalkonium chloride disinfectant at reducing the bacterial load on common touch-point surfaces in a high-traffic building (average 1.6 vs. 32.6 CFUs recovered from surfaces 90 min after application, respectively). Toxicology testing in rats confirmed GS-2 ingredients were rapidly cleared and posed no toxicities to humans or animals. To enhance the time-kill against Gram-positive bacteria, GS-2 was compounded at a specific ratio with a naturally occurring monoterpenoid, thymol, to produce a water-based antimicrobial solution. This GS-2 with thymol formulation could generate a bactericidal effect after five minutes of exposure and a viricidal effect after 10 min of exposure. Further testing of the GS-2 and thymol combination on glass slides demonstrated that the compound retained bactericidal activity for up to 60 days. Based on these results, GS-2 and GS-2 with thymol represent a novel antimicrobial solution that may have significant utility in the long-term reduction of environmental microbial pathogens in a variety of settings
The CCAP knowledgebase:Linking protistan and cyanobacterial biological resources with taxonomic and molecular data
Peer reviewedPublisher PD
Meter-Scale Chemical and Isotopic Heterogeneities in the Oceanic Mantle, Leka Ophiolite Complex, Norway
Mantle peridotites from three 3 x 3-meter grids sampled at kilometer distances from one another in the ca. 497 Ma Leka Ophiolite Complex (LOC), Norway, are examined to investigate the chemical and isotopic nature of oceanic mantle domains at the centimeter to kilometer scale. The lithology of each grid locality is predominantly harzburgite, but includes layers and lenses of dunite and pyroxenite. Major and lithophile trace element compositions indicate a history of prior melting at pressures at or slightly below the garnet stability field. The common presence of orthopyroxenite veins likely reflects infiltration of silicic melts associated with supra-subduction zone processes. Osmium isotopes and highly siderophile element (HSE) abundance data for centimeter-scale sampling of traverses from the pyroxenites into the harzburgites reveal that the formation of the veins had little effect on Os isotopic compositions, and Os, Ir, Ru and Re abundances in the harzburgites. Adjacent to one of the orthopyroxenite veins studied, however, Pt and Pd abundances appear to have been strongly modified by interactions with vein-forming melts or fluids at distances of as much as 4– 6 cm from the pyroxenite-harzburgite contact. Leka harzburgites have initial gammaOs values (% deviation from a chondritic reference) that range from -4.7 to +2.2 (6.9% variation), with individual uncertainties of 60.2 units. Averaged initial Os isotopic compositions for harzburgites from the three grid sites separated by as much as 6 km, by
contrast, differ by only a maximum of 2.6%. Isotopic heterogeneity on the centimeter to meter scale is, therefore, larger than kilometer-scale heterogeneity, indicating that at least some of the Os isotopic heterogeneity commonly observed globally among mantle peridotites is the result of processes that acted on a local scale. The general uniformity of these isotopic compositions among the three grid sites suggests that the portion of the oceanic mantle sampled by the LOC was homogenous at the kilometer scale with respect to the long-term Re/Os ratio. The long-term projected Re/Os for LOC harzburgites is similar to the average required for modern abyssal peridotites. This observation strengthens previous interpretations, based largely on data for
abyssal peridotites, that state the Os isotopic evolution of oceanic mantle is consistent with a long-term 187Re/188Os of ~0.38. The present ~3 to 4% difference between the Os isotopic composition of the modern oceanic mantle and estimates for primitive mantle suggests that at least ~6% of the mass of the oceanic mantle has been removed from it in the form of Re- enriched, mafic oceanic crust. Despite the recycling of this crust back into the mantle, most of it has evidently not been mixed back into accessible portions of the upper oceanic peridotite mantle. Compared to composition estimates for the primitive mantle, the median HSE compositions for the three grid sites are moderately to strongly depleted in Pd and Re, consistent with the corresponding lithophile element evidence for 20–30% melt depletion. As with initial cOs values, most harzburgites from a given grid are characterized by greater variations in absolute and relative HSE abundances than the differences between the median abundances of the three grid sampling locales. This observation indicates that as with Os isotopes, the HSE abundance heterogeneity among the harzburgites most strongly reflects centimeter- to meter-scale melting and remobilization effects.
Except for Ru, median HSE abundances for grid harzburgites are similar to median abundances for abyssal peridotites. The 30% lower median Ru/Ir in the LOC compared to the median ratio for abyssal peridotites suggests that the abundance of Ru in the oceanic mantle may be more variable than generally thought.This work was supported by National Science Foundation (NSF) Earth Science grants 1423879 (to RJW) and 1447130 (to J.M.D.D.), which are gratefully acknowledged. B.O’D. acknowledges support from a Royal Society Research
Grant (RG100528) and from Natural Environment Research Council (NERC) New Investigator grant NE/J00457X/1. J.S.D. gratefully acknowledges a University College Dublin Seed Funding Grant and Science Foundation Ireland Grant No. 13/RC/2092, which was co-funded under the European Regional Development Fund
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