Parent’s report on oral health-related quality of life of children with haemophilia

PubMedID: 30690828Introduction: Among children with haemophilia and their caregivers; problems arising from the teeth and the surrounding tissues have an important role in the treatment of this disease and it affects the quality of life of children and their parents. Aim: Aim of this study is to evaluate the oral health-related quality of life of children with haemophilia from the perspective of their parents. Methods: Paediatric oral health-related quality of life (POQL) instrument was used in this cross-sectional study for quality of life measurement. The research data collected by the questionnaire form were coded for scale items and personal information questions and transferred to SPSS, a multivariate statistical analysis program for social sciences. SPSS 23.0 (IBM Corp, Armonk, NY) package program was used for statistical analysis of the data. Results: Primary dentition dmft scores of patients with haemophilia are higher than the control group; mean value of haemophilic group is 3.5 vs control group are 2.6, respectively (P = 0.034). In spite of higher dmft scores, the haemophilia and control groups have shown no significant difference in oral health-related quality of life scores; median scores were 63.9 in haemophilic group and 85.3 in control group (P = 0.336), respectively. Conclusion: In spite of lower oral health measures, children with haemophilia and their parents reported no difference in oral health-related quality of life from their healthy counterparts. © 2019 John Wiley & Sons Lt

Seed structure of some taxa of the genus Crocus L. (iridaceae) series crocus

In this study, the macro-and micromorphological seed characteristics of the genus Crocus L. series Crocus taxa, including C. pallasii, C. turcicus, C. dispathaceus, C. asumaniae, C. mathewii, C. thomasii, C. oreocreticus, and C. cartwrightianus, were observed. Morphological characteristics, such as the size, shape, color, and seed surface structures, were analyzed using stereo and scanning electron microscopes. Testa layer structures including the outer and inner testae, phytomelan layer structure and thickness, and seed endosperm cell features were studied. Differences in the seed, raphe size, seed surface patterns, inner testa features, and phytomelan layer thickness were observed at an interspecific level. The results revealed differences in the seed morphology and anatomy with a few exceptions. © TÜBİTAK

Malnutrition, associated clinical factors, and depression in systemic sclerosis: a cross-sectional study

Introduction: The aim of this study was to evaluate the associations between malnutrition and the clinical features of the disease and depression in patients with systemic sclerosis (SSc). Method: Patients with SSc who were followed up in our clinic were enrolled in the study. Malnutrition risk was assessed using the Malnutrition Universal Screening Tool (MUST). Skin involvement was assessed using the modified Rodnan skin score (mRSS) and interincisal distance (ID) measurements were used to assess the maximal mouth opening capacity. The Beck Depression Inventory (BDI) was used for measuring the severity of depression. Results: Ninety-eight patients with SSc (84.7% women; mean age 52.67 ± 11.26 years) were included in the study. According to the MUST scores, 61.2%, 15.3%, and 23.5% of patients had low, medium, and high risk for malnutrition, respectively. The mRSS was significantly higher in the group with high malnutrition risk compared with low-risk group (p = 0.014). Malnutrition risk was associated with interstitial lung disease and bowel involvement (p = 0.044 and p = 0.021, respectively). Interincisal distance was lower in the group with high malnutrition risk compared with the low-risk group (p = 0.003). Malnutrition risk was higher in patients who had mild-to-severe depressive symptoms than in those without (p = 0.012). Interincisal distance and bowel involvement were the most relevant factors for malnutrition. Conclusions: The risk of malnutrition is increased in patients with SSc. In our study, microstomia and bowel involvement were the most relevantly associated factors with malnutrition. Key Points: • The risk of malnutrition is increased in patients with systemic sclerosis (SSc). • Microstomia and bowel involvement are found to be the most important factors associated with malnutrition. • Depressive symptoms are seen frequently among patients with SSc, and depression seems to be one of the etiologic factors or the result of malnourishment in SSc. • Assessment of nutritional status and the presence of depression should be a part of routine clinical visits of patients with SSc. © 2019, International League of Associations for Rheumatology (ILAR)

Supplementary Material for: A Retrospective analysis of 83 patients with testicular mass who underwent testis-sparing surgery: The Eurasian Uro-oncology Association Multicenter Study*

ABSTRACT Introduction: Herein,we analyzed the histopathological, oncologic and functional outcomes of TSS in patient with distinct risk for testicular cancer. Methods: This is a multicenter retrospective study on consecutive patients who underwent TSS. Patients were categorized in high- or low-risk Testicular Germ Cell Tumor(TGCT) according to the presence/absence of features compatible with Testicular Dysgenesis Syndrome(TDS). Histology was categorized per size and risk groups. Results: TSS was performed in 83 patients(86 tumors) of them, 27 in the high-risk group. Fifty-nine patients had a non-tumoral contralateral testis present. Sixty masses and 26 mases were benign and TGCTs respectively. No statistical differences were observed in mean age(30.9±10.32 years), pathological tumor size(14.67 ± 6.7 mm) between risk groups or between benign and malignant tumors(p=0.608). When categorized per risk groups 22(73.3%) and 4(7.1%) of the TSS specimens were malignant in the high- and low-risk patient groups respectively.Univariate analysis showed that the only independent variable significantly related to malignant outcome was previous history of TGCT. During a mean follow-up of 25.5±22.7 months no patient developed systemic disease. Local recurrence was detected in 5 patients and received RO. Postoperative testosterone levels remained normal in 88% of those patients with normal preoperative level. No ED was reported in patients with benign lesions. Conclusion: TSS is a safe and feasible approach with adequate cancer control and preservation of sexual function is possible in 2/3 of patients harboring malignancy. Incidence of TGCT varies extremely between patients at high and low risk for TGCT requiring a careful consideration and counseling