14 research outputs found

    Bio-analytical Assay Methods used in Therapeutic Drug Monitoring of Antiretroviral Drugs-A Review

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    The Cholecystectomy As A Day Case (CAAD) Score: A Validated Score of Preoperative Predictors of Successful Day-Case Cholecystectomy Using the CholeS Data Set

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    Background Day-case surgery is associated with significant patient and cost benefits. However, only 43% of cholecystectomy patients are discharged home the same day. One hypothesis is day-case cholecystectomy rates, defined as patients discharged the same day as their operation, may be improved by better assessment of patients using standard preoperative variables. Methods Data were extracted from a prospectively collected data set of cholecystectomy patients from 166 UK and Irish hospitals (CholeS). Cholecystectomies performed as elective procedures were divided into main (75%) and validation (25%) data sets. Preoperative predictors were identified, and a risk score of failed day case was devised using multivariate logistic regression. Receiver operating curve analysis was used to validate the score in the validation data set. Results Of the 7426 elective cholecystectomies performed, 49% of these were discharged home the same day. Same-day discharge following cholecystectomy was less likely with older patients (OR 0.18, 95% CI 0.15–0.23), higher ASA scores (OR 0.19, 95% CI 0.15–0.23), complicated cholelithiasis (OR 0.38, 95% CI 0.31 to 0.48), male gender (OR 0.66, 95% CI 0.58–0.74), previous acute gallstone-related admissions (OR 0.54, 95% CI 0.48–0.60) and preoperative endoscopic intervention (OR 0.40, 95% CI 0.34–0.47). The CAAD score was developed using these variables. When applied to the validation subgroup, a CAAD score of ≤5 was associated with 80.8% successful day-case cholecystectomy compared with 19.2% associated with a CAAD score >5 (p < 0.001). Conclusions The CAAD score which utilises data readily available from clinic letters and electronic sources can predict same-day discharges following cholecystectomy

    Quality Improvements for Ensuring e-Retailing Success in India: Constructs and Frameworks

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    Part 7: Shorter PapersInternational audienceThis extended abstract presents a review of various constructs and evaluation frameworks proposed in the literature for e-Retailers. Our study shows that the existing frameworks apply to either the technical or the non-technical elements of an e-Retailing site and not both of them. Therefore, a comprehensive framework covering all aspects of quality is what is required. Furthermore, for the long run sustenance and growth of e-Retailing, it is necessary to focus on the service provided and not only the technical aspects. In the Indian context, where e-Retailing is beginning to enter a rapid growth phase, evaluation methods and metrics which are appropriate are necessary. Our extended abstract highlights the key issues that will help define these constructs

    Recent Advancements in High-Performance Solid Electrolytes for Li-ion Batteries: Towards a Solid Future

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