Social Inequality And Common Mental Disorders.

OBJECTIVE: To analyze the association between the socioeconomic characteristics of individuals and common mental disorders. METHOD: A cross-sectional survey of a representative sample of the urban population, 14 years and older, in Campinas (Brazil) (n=515) was conducted using a multipurpose instrument that included the Self-Reporting Questionnaire (SRQ-20) to assess common mental disorders in the previous 3 months. Weighted prevalence of common mental disorders was calculated for each independent variable. Crude and adjusted prevalence ratios were estimated using Poisson regression. RESULTS: The overall prevalence was 17% (95% CI 12.8-22.3), 8.9% in males and 24.4% in females. An inverse association was found between common mental disorders and the socioeconomic characteristics (schooling and employment) even after controlling for all the other variables. Higher common mental disorders prevalence was observed in those with less than 5 years of schooling (PR=5.5) and unemployed or underemployed (PR=2.0). CONCLUSIONS: As in other studies, common mental disorders were unevenly distributed; it was significantly more frequent in socially disadvantaged individuals. Specific actions to reduce inequalities in the general and mental health system should be studied.29325025

Nonlinear parametric instability in double-well lattices

A possibility of a nonlinear resonant instability of uniform oscillations in dynamical lattices with harmonic intersite coupling and onsite nonlinearity is predicted. Numerical simulations of a lattice with a double-well onsite anharmonic potential confirm the existence of the nonlinear instability with an anomalous value of the corresponding power index, 1.57, which is intermediate between the values 1 and 2 characterizing the linear and nonlinear (quadratic) instabilities. The anomalous power index may be a result of competition between the resonant quadratic instability and nonresonant linear instabilities. The observed instability triggers transition of the lattice into a chaotic dynamical state.Comment: A latex text file and three pdf files with figures. Physical Review E, in pres

Isotopic Scaling of Heavy Projectile Residues from the collisions of 25 MeV/nucleon 86Kr with 124Sn, 112Sn and 64Ni, 58Ni

The scaling of the yields of heavy projectile residues from the reactions of 25 MeV/nucleon 86Kr projectiles with 124Sn,112Sn and 64Ni, 58Nitargets is studied. Isotopically resolved yield distributions of projectile fragments in the range Z=10-36 from these reaction pairs were measured with the MARS recoil separator in the angular range 2.7-5.3 degrees. The velocities of the residues, monotonically decreasing with Z down to Z~26-28, are employed to characterize the excitation energy. The yield ratios R21(N,Z) for each pair of systems are found to exhibit isotopic scaling (isoscaling), namely, an exponential dependence on the fragment atomic number Z and neutron number N. The isoscaling is found to occur in the residue Z range corresponding to the maximum observed excitation energies. The corresponding isoscaling parameters are alpha=0.43 and beta=-0.50 for the Kr+Sn system and alpha=0.27 and beta=-0.34 for the Kr+Ni system. For the Kr+Sn system, for which the experimental angular acceptance range lies inside the grazing angle, isoscaling was found to occur for Z<26 and N<34. For heavier fragments from Kr+Sn, the parameters vary monotonically, alpha decreasing with Z and beta increasing with N. This variation is found to be related to the evolution towards isospin equilibration and, as such, it can serve as a tracer of the N/Z equilibration process. The present heavy-residue data extend the observation of isotopic scaling from the intermediate mass fragment region to the heavy-residue region. Such high-resolution mass spectrometric data can provide important information on the role of isospin in peripheral and mid-peripheral collisions, complementary to that accessible from modern large-acceptance multidetector devices.Comment: 8 pages, 6 figures, submitted to Phys. Rev.

Inativação seletiva de esporos mantendo atividade larvicida em Bt sorovar israelensis irradiada com raios gama

Bacillus thuringiensis is used to produce biopesticides against target-insects of importance in agroindustry and human health. However, B. thuringiensis can carry the same enterotoxin-encoding genes as Bacillus cereus, suggesting a potential risk of food poisoning. The objective of this work was to study the application of gamma radiation to eliminate spores in biopesticides based on B. thuringiensis serovar israelensis in order to avoid the liberation of these spores in the environment. The application of 20 kGy of radiation ensures total inactivation of the spores in the insecticide without changing the larvicidal activity. Results showed that it is possible to develop formulations containing B. thuringiensis serovar israelensis (IPS-82) eliminating viable spores with gamma radiation without affecting the larvicidal activity. Irradiated formulations would be safer for the environment and humans since the elimination of viable spores abolishes the pathogenic potential of B. thuringiensis strains.Keywords: biopesticides, gamma radiation, larvicidal insecticides.Bacillus thuringiensis é usado na produção de biopesticidas contra insetos-alvo de importância na agroindústria e na saúde pública. Contudo, B. thuringiensis pode apresentar os mesmos genes codificadores de enterotoxinas presentes em Bacillus cereus, sugerindo a possível existência de risco para intoxicação alimentar. O objetivo deste trabalho foi estudar a aplicação de radiação gama para a eliminação de esporos em preparações de biopesticidas de B. thuringiensis sorovar israelensis de forma a se evitar a liberação de esporos viáveis no ambiente. Observou-se que a aplicação de 20 kGy garante a inativação total dos esporos no inseticida sem que haja mudança na atividade larvicida. Os resultados obtidos demonstram que é possível desenvolver formulações contendo B. thuringiensis sorovar israelensis (IPS-82) eliminando-se esporos viáveis sem alteração da atividade larvicida. As formulações irradiadas seriam mais seguras para o meio-ambiente e para seres humanos uma vez que a eliminação dos esporos viáveis neutraliza o potencial patogênico de cepas de B. thuringiensis.Palavras-chave: biopesticidas, radiação gama, inseticidas larvicidas

First international new intravascular rigid-flex endovascular stent study (FINESS): Clinical and angiographic results after elective and urgent stent implantation

Objectives. The purpose of this study was to determine the feasibility, safety and efficacy of elective and urgent deployment of the new intravascular rigid-flex (NIR) stent in patients with coronary artery disease. Background. Stent implantation has been shown to be effective in the treatment of focal, new coronary stenoses and in restoring coronary flow after coronary dissection and abrupt vessel closure. However, currently available stents either lack flexibility, hindering navigation through tortuous arteries, or lack axial strength, resulting in suboptimal scaffolding of the vessel. The unique transforming multicellular design of the NIR stent appears to provide both longitudinal flexibility and radial strength. Methods. NIR stent implantation was attempted in 255 patients (341 lesions) enrolled prospectively in a multicenter international registry from December 1995 through March 1996. Nine-, 16- and 32-mm long NIR stents were manually crimped onto coronary balloons and deployed in native coronary (94%) and saphenous vein graft (6%) lesions. Seventy-four percent of patients underwent elective stenting for primary or restenotic lesions, 21% for a suboptimal angioplasty result and 5% for threatened or abrupt vessel closure. Fifty-two percent of patients presented with unstable angina, 48% had a previous myocardial infarction, and 45% had multivessel disease. Coronary lesions were frequently complex, occurring in relatively small arteries (mean [±SD] reference diameter 2.8 ± 0.6 mm). Patients were followed up for 6 months for the occurrence of major adverse cardiovascular events. Results. Stent deployment was accomplished in 98% of lesions. Mean minimal lumen diameter increased by 1.51 ± 0.51 mm (from 1.09 ± 0.43 mm before to 2.60 ± 0.50 mm after the procedure). Mean percent diameter stenosis decreased from 61 ± 13% before to 17 ± 7% after intervention. A successful interventional procedure with <50% diameter stenosis of all treatment site lesions and no major adverse cardiac events within 30 days occurred in 95% of patients. Event-free survival at 6 months was 82%. Ninety-four percent of surviving patients were either asymptomatic or had mild stable angina at 6 month follow-up. Conclusions. Despite unfavorable clinical and angiographic characteristics of the majority of patients enrolled, the acute angiographic results and early clinical outcome after NIR stent deployment were very promising. A prospective, randomized trial comparing the NIR stent with other currently available stents appears warranted

The rationale for heart team decision-making for patients with stable, complex coronary artery disease

Stable complex coronary artery disease can be treated with coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), or medical therapy. Multidisciplinary decision-making has gained more emphasis over the recent years to select the most optimal treatment strategy for individual patients with stable complex coronary artery disease. However, the so-called 'Heart Team' concept has not been widely implemented. Yet, decision-making has shown to remain suboptimal; there is large variability in PCI-to-CABG ratios, which may predominantly be the consequence of physician-related factors that have raised concerns regarding overuse, underuse, and inappropriate selection of revascularization. In this review, we summarize these and additional data to support the statement that a multidisciplinary Heart Team consisting of at least a clinical/non-invasive cardiologist, interventional cardiologist, and cardiac surgeon, can together better analyse and interpret the available diagnostic evidence, put into context the clinical condition of the patient as well as consider individual preference and local expertise, and through shared decision-making with the patient can arrive at a most optimal joint treatment strategy recommendation for patients with stable co

Atherosclerotic coronary lesions with inadequate compensatory enlargement have smaller plaque and vessel volumes: observations with three dimensional intravascular ultrasound in vivo.

OBJECTIVE: To compare vessel, lumen, and plaque volumes in atherosclerotic coronary lesions with inadequate compensatory enlargement versus lesions with adequate compensatory enlargement. DESIGN: 35 angiographically significant coronary lesions were examined by intravascular ultrasound (IVUS) during motorised transducer pullback. Segments 20 mm in length were analysed using a validated automated three dimensional analysis system. IVUS was used to classify les

The torsion cosmology in Kaluza-Klein theory

We have studied the torsion cosmology model in Kaluza-Klein theory. We considered two simple models in which the torsion vectors are $A_{\mu}=(\alpha,0,0,0)$ and $A_{\mu}=a(t)^2(0,\beta,\beta,\beta)$, respectively. For the first model, the accelerating expansion of the Universe can be not explained without dark energy which is similar to that in the standard cosmology. But for the second model, we find that without dark energy the effect of torsion can give rise to the accelerating expansion of the universe and the alleviation of the well-known age problem of the three old objects for appropriated value of the model parameter $\beta$. These outstanding features of the second torsion cosmology model have been supported by the Type Ia supernovae (SNIa) data.Comment: 12 pages, 2 figures. Accepted for publication in JCA