635 research outputs found
Supersymmetry Unification Predictions for M_top V_cb and tan(beta)
We study the predictions for M_top, tan(beta) and V_cb in a popular texture
ansatze for the fermion mass matrices. We do this both for the Minimal
Supersymmetric Standard Model (MSSM) and for the simplest model (MSSM-BRpV)
where a bilinear R-Parity violating term is added to the superpotential. We
find that taking the experimental values for M_top and V_cb at 99 % C.L. and
the GUT relations h_b=h_tau and (V_cb)^2=h_c/h_t within 5 %, the large
tan(beta) solution, characteristic in the MSSM with bottom--tau unification,
becomes disallowed. In contrast the corresponding allowed region for the
MSSM-BRpV is slightly larger. We also find that important modifications occur
if we relax the texture conditions at the GUT scale. For example, if the GUT
relations are imposed at 40 %, the large tan(beta) branch in the MSSM becomes
fully allowed. In addition, in MSSM-BRpV the whole tan(beta)-M_top plane become
allowed, finding unification at any value of tan(beta).Comment: 15 pages, including 6 figures. Late
Autophagy activation can partially rescue proteasome dysfunction-mediated cardiac toxicity.
The ubiquitin-proteasome pathway and its functional interplay with other proteostatic and/or mitostatic modules are crucial for cell viability, especially in post-mitotic cells like cardiomyocytes, which are constantly exposed to proteotoxic, metabolic, and mechanical stress. Consistently, treatment of multiple myeloma patients with therapeutic proteasome inhibitors may induce cardiac failure; yet the effects promoted by heart-targeted proteasome dysfunction are not completely understood. We report here that heart-targeted proteasome knockdown in the fly experimental model results in increased proteome instability and defective mitostasis, leading to disrupted cardiac activity, systemic toxicity, and reduced longevity. These phenotypes were partially rescued by either heart targeted- or by dietary restriction-mediated activation of autophagy. Supportively, activation of autophagy by Rapamycin or Metformin administration in flies treated with proteasome inhibitors reduced proteome instability, partially restored mitochondrial function, mitigated cardiotoxicity, and improved flies' longevity. These findings suggest that autophagic inducers represent a novel promising intervention against proteasome inhibitor-induced cardiovascular complications
Extra Dimensions at the Weak Scale and Deviations from Newtonian Gravity
We consider theories in which the Standard Model gauge fields propagate in
extra dimensions whose size is around the electroweak scale. The Standard Model
quarks and leptons may either be localized to a brane or propagate in the bulk.
This class of theories includes models of Scherk-Schwarz supersymmetry
breaking and universal extra dimensions. We consider the problem of stabilizing
the volume of the extra dimensions. We find that for a large class of
stabilization mechanisms the field which corresponds to fluctuations of the
volume remains light even after stabilization, and has a mass in the
eV range. In particular this is the case if stabilization does not involve
dynamics at scales larger than the cutoff of the higher dimensional Standard
Model, and if the effective theory below the compactification scale is four
dimensional. The mass of this field is protected against large radiative
corrections by the general covariance of the higher dimensional theory and by
the weakness of its couplings, which are Planck suppressed. Its couplings to
matter mediate forces whose strength is comparable to that of gravity and which
can give rise to potentially observable deviations from Newton's Law at
sub-millimeter distances. Current experiments investigating short distance
gravity can probe extra dimensions too small to be accessible to current
collider experiments. In particular for a single extra dimension stabilized by
the Casimir energy of the Standard Model fields compactification radii as small
as 5 inverse TeV are accessible to current sub-millimeter gravity experiments.Comment: Minor corrections, conclusions unchanged. References adde
Scattering off an SO(10) cosmic string
The scattering of fermions from the abelian string arising during the phase
transition induced by the Higgs in the
126 representation is studied. Elastic cross-sections and baryon number
violating cross-sections due to the coupling to gauge fields in the core of the
string are computed by both a first quantised method and a perturbative second
quantised method. The elastic cross-sections are found to be Aharonov-Bohm
type. However, there is a marked asymmetry between the scattering
cross-sections for left and right handed fields. The catalysis cross-sections
are small, depending on the grand unified scale. If cosmic strings were
observed our results could help tie down the underlying gauge group.Comment: 20 page
The Formation of Cosmic Structures in a Light Gravitino Dominated Universe
We analyse the formation of cosmic structures in models where the dark matter
is dominated by light gravitinos with mass of eV -- 1 keV, as predicted
by gauge-mediated supersymmetry (SUSY) breaking models. After evaluating the
number of degrees of freedom at the gravitinos decoupling (), we compute
the transfer function for matter fluctuations and show that gravitinos behave
like warm dark matter (WDM) with free-streaming scale comparable to the galaxy
mass scale. We consider different low-density variants of the WDM model, both
with and without cosmological constant, and compare the predictions on the
abundances of neutral hydrogen within high-redshift damped Ly-- systems
and on the number density of local galaxy clusters with the corresponding
observational constraints. We find that none of the models satisfies both
constraints at the same time, unless a rather small value (\mincir
0.4) and a rather large Hubble parameter (\magcir 0.9) is assumed.
Furthermore, in a model with warm + hot dark matter, with hot component
provided by massive neutrinos, the strong suppression of fluctuation on scales
of \sim 1\hm precludes the formation of high-redshift objects, when the
low-- cluster abundance is required. We conclude that all different variants
of a light gravitino DM dominated model show strong difficulties for what
concerns cosmic structure formation.
This gives a severe cosmological constraint on the gauge-mediated SUSY
breaking scheme.Comment: 28 pages,Latex, submitted for publication to Phys.Rev.
Collider signals from slow decays in supersymmetric models with an intermediate-scale solution to the mu problem
The problem of the origin of the mu parameter in the Minimal Supersymmetric
Standard Model can be solved by introducing singlet supermultiplets with
non-renormalizable couplings to the ordinary Higgs supermultiplets. The
Peccei-Quinn symmetry is broken at a scale which is the geometric mean between
the weak scale and the Planck scale, yielding a mu term of the right order of
magnitude and an invisible axion. These models also predict one or more singlet
fermions which have electroweak-scale masses and suppressed couplings to MSSM
states. I consider the case that such a singlet fermion, containing the axino
as an admixture, is the lightest supersymmetric particle. I work out the
relevant couplings in several of the simplest models of this type, and compute
the partial decay widths of the next-to-lightest supersymmetric particle
involving leptons or jets. Although these decays will have an average proper
decay length which is most likely much larger than a typical collider detector,
they can occasionally occur within the detector, providing a striking signal.
With a large sample of supersymmetric events, there will be an opportunity to
observe these decays, and so gain direct information about physics at very high
energy scales.Comment: 24 pages, LaTeX, 4 figure
Stationary Einstein-Maxwell fields in arbitrary dimensions
The Einstein-Maxwell equations in D-dimensions admitting (D-3) commuting
Killing vector fields have been investigated. The existence of the electric,
magnetic and twist potentials have been proved. The system is formulated as the
harmonic map coupled to gravity on three-dimensional base space generalizing
the Ernst system in the four-dimensional stationary Einstein-Maxwell theory.
Some classes of the new exact solutions have been provided, which include the
electro-magnetic generalization of the Myers-Perry solution, which describes
the rotating black hole immersed in a magnetic universe, and the static charged
black ring solution.Comment: 26 page
Phenomenology of the Little Higgs Model
We study the low energy phenomenology of the little Higgs model. We first
discuss the linearized effective theory of the "littlest Higgs model" and study
the low energy constraints on the model parameters. We identify sources of the
corrections to low energy observables, discuss model-dependent arbitrariness,
and outline some possible directions of extensions of the model in order to
evade the precision electroweak constraints. We then explore the characteristic
signatures to test the model in the current and future collider experiments. We
find that the LHC has great potential to discover the new SU(2) gauge bosons
and the possible new U(1) gauge boson to the multi-TeV mass scale. Other states
such as the colored vector-like quark T and doubly-charged Higgs boson Phi^{++}
may also provide interesting signals. At a linear collider, precision
measurements on the triple gauge boson couplings could be sensitive to the new
physics scale of a few TeV. We provide a comprehensive list of the linearized
interactions and vertices for the littlest Higgs model in the appendices.Comment: 43 pages, 6 figures; v2: discussion clarified, typos corrected; v3:
version to appear in PRD; v4: typos fixed in Feynman rule
Flavon exchange effects in models with abelian flavor symmetry
In models with abelian flavor symmetry the small mixing angles and mass
ratios of quarks and leptons are typically given by powers of small parameters
characterizing the spontaneous breaking of flavor symmetry by "flavon" fields.
If the scale of the breaking of flavor symmetry is near the weak scale, flavon
exchange can lead to interesting flavor-violating and CP violating effects.
These are studied. It is found that d_e, mu -> e + gamma, and mu-e conversion
on nuclei can be near present limits. For significant range of parameters mu-e
conversion can be the most sensitive way to look for such effects.Comment: 19 pages, 5 Postscript figures, LATE
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