The design and relevance of a computerised therapy program for indigenous Māori adolescents.

Background: Depression is a major health issue among Māori indigenous adolescents, yet there has been little investigation into the relevance or effectiveness of psychological treatments for them. Further, consumer views are critical for engagement and adherence to therapy. However, there is little research regarding indigenous communities’ opinions about psychological interventions for depression. Objective: The objective of this study was to conduct semistructured interviews with Māori (indigenous New Zealand) young people (taitamariki) and their families to find out their opinions of a prototype computerized cognitive behavioral therapy (cCBT) program called Smart, Positive, Active, Realistic, X-factor thoughts (SPARX), a free online computer game intended to help young persons with mild to moderate depression, feeling down, stress or anxiety. The program will teach them how to resolve their issues on their own using Cognitive Behavioural Therapy as psychotherapeutic approach. Methods: There were seven focus groups on the subject of the design and cultural relevance of SPARX that were held, with a total of 26 participants (19 taitamarki, 7 parents/caregivers, all Māori). There were five of the groups that were with whānau (family groups) (n=14), one group was with Māori teenage mothers (n=4), and one group was with taitamariki (n=8). The general inductive approach was used to analyze focus group data. Results: SPARX computerized therapy has good face validity and is seen as potentially effective and appealing for Māori people. Cultural relevance was viewed as being important for the engagement of Māori young people with SPARX. Whānau are important for young peoples’ well-being. Participants generated ideas for improving SPARX for Māori and for the inclusion of whānau in its delivery. Conclusions: SPARX computerized therapy had good face validity for indigenous young people and families. In general, Māori participants were positive about the SPARX prototype and considered it both appealing and applicable to them. The results of this study were used to refine SPARX prior to it being delivered to taitamariki and non-Māori young people

Electrical conductivity for Copper Oxide (CuO) nanofluids in the superconducting phase. A generalization of Type II superconductivity hydrodynamics behavior

This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, Aristotle University of Thessaloniki, University of Thessaly, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute.Copper oxide superconducting nanofluids exhibit a lot of very interesting technological properties and their behaviour is typical of a two- phase nanofluid. Near the superconductivity trasition temperature, their electrical conductivity is the sum of a normal conductivity component and a flux flow superconducting contribution from the unpinned motion of vortices within the sample. Armed with recent experimental results for regular type II superconductivity nanosamples, we review the corresponding expected behaviour for CuO High Temperature Superconducting (HTSC) systems. The equivalent Navier-Stokes equations that go under the name Ginzburg–Landau equations for the superconducting density are briefly reviewed and their solutions are presented in a clear way for the particular problem. Contribution of fluctuations of the structural vortex lattice, which is a stable solution of the Time Dependent Ginzburg-Landau (TDGL) equations, to the flux flow two -phase conductivity is briefly presented. The corresponding discussion for the two-phase thermal conductivity of a superconducting nanosample is going to be presented in a separate future publication

Using keystroke logging to understand writers’ processes on a reading-into-writing test

Background Integrated reading-into-writing tasks are increasingly used in large-scale language proficiency tests. Such tasks are said to possess higher authenticity as they reflect real-life writing conditions better than independent, writing-only tasks. However, to effectively define the reading-into-writing construct, more empirical evidence regarding how writers compose from sources both in real-life and under test conditions is urgently needed. Most previous process studies used think aloud or questionnaire to collect evidence. These methods rely on participants’ perceptions of their processes, as well as their ability to report them. Findings This paper reports on a small-scale experimental study to explore writers’ processes on a reading-into-writing test by employing keystroke logging. Two L2 postgraduates completed an argumentative essay on computer. Their text production processes were captured by a keystroke logging programme. Students were also interviewed to provide additional information. Keystroke logging like most computing tools provides a range of measures. The study examined the students’ reading-into-writing processes by analysing a selection of the keystroke logging measures in conjunction with students’ final texts and interview protocols. Conclusions The results suggest that the nature of the writers’ reading-into-writing processes might have a major influence on the writer’s final performance. Recommendations for future process studies are provided

The mystery of relationship of mechanics and field in the many-body quantum world

We have revealed three fatal errors incurred from a blind transferring of quantum field methods into the quantum mechanics. This had tragic consequences because it produced crippled model Hamiltonians, unfortunately considered sufficient for a description of solids including superconductors. From there, of course, Fr\"ohlich derived wrong effective Hamiltonian, from which incorrect BCS theory arose. 1) Mechanical and field patterns cannot be mixed. Instead of field methods applied to the mechanical Born-Oppenheimer approximation we have entirely to avoid it and construct an independent and standalone field pattern. This leads to a new form of the Bohr's complementarity on the level of composite systems. 2) We have correctly to deal with the center of gravity, which is under the field pattern "materialized" in the form of new quasipartiles - rotons and translons. This leads to a new type of relativity of internal and external degrees of freedom and one-particle way of bypassing degeneracies (gap formation). 3) The possible symmetry cannot be apriori loaded but has to be aposteriori obtained as a solution of field equations, formulated in a general form without translational or any other symmetry. This leads to an utterly revised view of symmetry breaking in non-adiabatic systems, namely Jahn-Teller effect and superconductivity. These two phenomena are synonyms and share a unique symmetry breaking.Comment: 24 pages, 9 sections; remake of abstract, introduction and conclusion; more physics, less philosoph

Pengaruh Primatani terhadap Peningkatan Pendapatan Petani Perkebunan di Kecamatan Busungbiu

In 2006 up to 2009, Assessment Institue for Agriculture Technology (AIAT) of Bali, conducted Primatani assessment in Busungbiu district. There are several technologies introduced in the study, namely: (1) improvement of cultivation technology of coffee, cocoa, and goats, (2) processing of coffee and cocoa waste into animal feed, (3) processing of goat manure into organic fertilizer, and (4 ) processing of integration farming products. In this regard, the research aims to analyze the influence of Primatani to: (1) farmers income, (2) the extention of farmers income, (3) contribution of the integration farming income to totally farm household income, (4) employment; ( 5) farmers income distribution, and (6) the factors that influence farming integration income. The research was conducted in the Sepang and Pucaksari villages in July to September 2013. Respondents are farmers who implemented farming integration of Robusta coffee plants and goats. They are determined by disproportional random sampling. Respondents were divided into two groups, namely: the Primatani cooperators and not Primatani cooperators group. Number of samples are determined by Slovin theory. The data is collected by surveys. The data was analyzed by independent samples t-test, Lorenz curve, Gini coefficient, and Structural Quation Modeling of Partial Least Square method. The result of analysis showed, (1) the integration farming income in the Primatani cooperators group higher than not Primatani cooperators group; (2) sources of income in the Primatani cooperators group more than not Primatani cooperators group; (3) contribution of integration farming income to total income of household farmers in both sample groups are relatively equal, (4) sum of employ in the Primatani cooperators group higher than not Primatani cooperators group; (5) equitable distribution of income, and (6) factor of coffee plantation and goats farming influence on integration farming income

Pre-mRNA Splicing Modulation by Antisense Oligonucleotides

Pre-mRNA splicing, a dynamic process of intron removal and exon joining, is governed by a combinatorial control exerted by overlapping cis-elements that are unique to each exon and its flanking intronic sequences. Splicing cis-elements are usually 4-to-8-nucleotide-long linear motifs that provide binding sites for specific proteins. Pre-mRNA splicing is also influenced by secondary and higher order RNA structures that affect accessibility of splicing cis-elements. Antisense oligonucleotides (ASOs) that block splicing cis-elements and/or affect RNA structure have been shown to modulate splicing in vivo. Therefore, ASO-based strategies have emerged as a powerful tool for therapeutic manipulation of splicing in pathological conditions. Here we describe an ASO-based approach to increase the production of the full-length SMN2 mRNA in spinal muscular atrophy patient cells