Eräiden rikkakasvihävitteiden teho perunalla

Compared to the untreated control the use fo various herbicides has given yield increases of 6 11 tons per hectare. Prometryne (Gesagard 50) and terbutryne (Igran 50) gave highly significant differences in results compared to the untreated control. The effects of various chemicals, however, did not differ from each other significantly. On the average, the best weed control and highest yield increases were obtained with linuron, followed by terbutryne and prometryn. Results of MCPA and cyanazine were not as good. Prometryne and cyanazine did not have an equally good effect on weeds, and probably for this reason, they did not give good yield results consistently

Levosimendan versus Milrinone for Inotropic Support in Pediatric Cardiac Surgery: Results from a Randomized Trial

Objective : We aimed to determine the differential effects of intra-operative administration of milrinone versus levosimendan on myocardial function after pediatric cardiac surgery. Transthoracic echocardiography was employed for myocardial function evaluation, utilizing biventricular longitudinal strain with two-dimensional speckle tracking echocardiography in addition to conventional echocardiographic variables. Design : A secondary analysis of a randomized, prospective, double-blinded clinical drug trial Setting : Two pediatric tertiary university hospitals Participants : Infants between 1-12 months of age diagnosed with ventricular septal defect, complete atrioventricular septal defect, or tetralogy of Fallot who were scheduled for corrective surgery with cardiopulmonary bypass. Interventions : The patients were randomized to receive an infusion of milrinone or levosimendan at the start of cardiopulmonary bypass and for 26 consecutive hours. Measurements and main results : Biventricular longitudinal strain and conventional echocardiographic variables were measured preoperatively, on the first postoperative morning and prior to hospital discharge. The association between perioperative parameters and postoperative myocardial function was also investigated. Images were analyzed for left ventricular (n=67) and right ventricular (n=44) function. The day after surgery, left ventricular longitudinal strain was deteriorated in both the milrinone and levosimendan groups; 33% and 39%, respectively. The difference was not significant. The corresponding deterioration in right ventricular longitudinal strain was 42% and 50% (non-significant difference). For both groups, biventricular longitudinal strain approached their preoperative values at hospital discharge. Preoperative N-terminal pro-brain natriuretic peptide could predict the left ventricular strain on postoperative day one (p=0.014). Conclusions : Levosimendan was comparable to milrinone for left and right ventricular inotropic support in pediatric cardiac surgery.Peer reviewe

Syysviljojen talvituhosienien torjunta PCNB:llä

Tehdyissä kokeissa vuosina 1966—69 on Kotkaniemen koetilalla Vihdissä saatu PCNB-käsittelyllä useimmiten huomattavia sadonlisäyksiä rukiilla ja syysvehnällä. Alustavat kokeet osoittavat, että 50 %:sen PCNB-ruiskutejauheen, joka sisältää täyteaineena ammoniumsulfaattia, levitys alkutalven löyhälle lumelle tai sijoitus lumen läpi rivilannoituskoneella lannoitteeseen sekoitettuna maan pinnalle, antaa yhtä hyviä tuloksia kuin ennen lumen tuloa tapahtunut levityskin

Recessive TMOD1 mutation causes childhood cardiomyopathy.

Familial cardiomyopathy in pediatric stages is a poorly understood presentation of heart disease in children that is attributed to pathogenic mutations. Through exome sequencing, we report a homozygous variant in tropomodulin 1 (TMOD1; c.565C>T, p.R189W) in three individuals from two unrelated families with childhood-onset dilated and restrictive cardiomyopathy. To decipher the mechanism of pathogenicity of the R189W mutation in TMOD1, we utilized a wide array of methods, including protein analyses, biochemistry and cultured cardiomyocytes. Structural modeling revealed potential defects in the local folding of TMOD1R189W and its affinity for actin. Cardiomyocytes expressing GFP-TMOD1R189W demonstrated longer thin filaments than GFP-TMOD1wt-expressing cells, resulting in compromised filament length regulation. Furthermore, TMOD1R189W showed weakened activity in capping actin filament pointed ends, providing direct evidence for the variant's effect on actin filament length regulation. Our data indicate that the p.R189W variant in TMOD1 has altered biochemical properties and reveals a unique mechanism for childhood-onset cardiomyopathy

Syysviljojen talvituhosienien torjunta PCNB:llä

vokKirjasto Aj-KControl of low temperature parasitic fungi PCN

Syysviljojen talvituhosienien torjunta PCNB:llä

In the tests on the Kotkaniemi Experimental Farm at Vihti in 1966—69 PCNB-treatments in most cases gave considerable increases in grain yields of rye and winter wheat. In addition to customary treatments, research has been carried out the possibility of reducing the loss of PCNB in rains in the autumn by using a fixing material. The results of the tests are negative, however. The spreading of 50 % PCNB-spray powder, containing ammonium sulphate as filling material, on the loose snow or the placement of PCNB with a fertilizer under the snow in early winter has in the preliminary tests given as good results as spreading before the fall of snow. The results indicate that the time of the PCNB-treatment may safely be postponed to a later date than is customary at present.Tehdyissä kokeissa vuosina 1966—69 on Kotkaniemen koetilalla Vihdissä saatu PCNB-käsittelyllä useimmiten huomattavia sadonlisäyksiä rukiilla ja syysvehnällä. Alustavat kokeet osoittavat, että 50 %:sen PCNB-ruiskutejauheen, joka sisältää täyteaineena ammoniumsulfaattia, levitys alkutalven löyhälle lumelle tai sijoitus lumen läpi rivilannoituskoneella lannoitteeseen sekoitettuna maan pinnalle, antaa yhtä hyviä tuloksia kuin ennen lumen tuloa tapahtunut levityskin

Speckle tracking echocardiography detects decreased cardiac longitudinal function in anthracycline-exposed survivors of childhood cancer

Longitudinal motion significantly contributes to the contraction of the ventricles. We studied the left (LV) and right ventricular (RV) longitudinal functions in 75 anthracycline-exposed, long-term childhood cancer survivors and 75 healthy controls with conventional echocardiography, tissue Doppler imaging (TDI), speckle tracking echocardiography (STE) of the mitral and tricuspid annular motion, and real-time three-dimensional echocardiography (RT-3DE). Cardiac magnetic resonance (CMR) imaging was performed on 61 of the survivors. The survivors had lower systolic myocardial velocities in the LV and lower diastolic velocities in both ventricles by TDI than did their healthy peers. The STE-based tissue motion annular displacement (TMAD) values describing the LV and RV systolic longitudinal function (MAD and TAD mid%, respectively) were also lower among the survivors (15.4 +/- 2.4 vs. 16.1 +/- 2.2 %, p = 0.049 and 22.5 +/- 3.0 vs. 23.5 +/- 3.0 %, p = 0.035). MAD and TAD mid in millimeters correlated with the respective ventricular volumes measured with RT-3DE or CMR. Conclusion: Childhood cancer survivors exposed to low to moderate anthracycline doses had decreased longitudinal systolic and diastolic functions (TDI or STE) compared with healthy controls. The STE-based TMAD is a fast and reproducible method to assess cardiac longitudinal function.Peer reviewe