Method of forming a skeletal dome structure in situ

A skeletal dome structure composed of a plurality of arcuate support beams joined at their upper ends to a central hub and radiating outwardly and downwardly to terminate at points of engagement with a support surface. Each support beam is composed of an elongated lightweight core sandwiched between upper and lower strips of a material having high tensile and compressive strength. In making the dome, each beam is first preassembled to the extent that the core thereof is secured to a first strip, that strip is then attached at one end to the central hub, the first strip and core are then longitudinally flexed to develop a convex curvature along the side of the core opposite from the strip, and a second flexible strip is then secured to the convex side of the core. A plurality of such beams may be simultaneously formed into buckled or arcuate shape by connecting a plurality of the first strips to a single hub and then raising the hub to impart a curvature into each of the partially-finished beams, followed by the final step of securing the outer strips or skins to the convex upper surfaces of all of the outwardly-radiating arcuate members

Implementation of polarization diversity pulse-pair technique using airborne W-band radar

This work describes the implementation of polarization diversity on the National Research Council Canada W-band Doppler radar and presents the first-ever airborne Doppler measurements derived via polarization diversity pulse-pair processing. The polarization diversity pulse-pair measurements are interleaved with standard pulse-pair measurements with staggered pulse repetition frequency, this allows a better understanding of the strengths and drawbacks of polarization diversity, a methodology that has been recently proposed for wind-focused Doppler radar space missions. Polarization diversity has the clear advantage of making possible Doppler observations of very fast decorrelating media (as expected when deploying Doppler radars on fast-moving satellites) and of widening the Nyquist interval, thus enabling the observation of very high Doppler velocities (up to more than 100 m s−1 in the present work). Crosstalk between the two polarizations, mainly caused by depolarization at backscattering, deteriorated the quality of the observations by introducing ghost echoes in the power signals and by increasing the noise level in the Doppler measurements. In the different cases analyzed during the field campaigns, the regions affected by crosstalk were generally associated with highly depolarized surface returns and depolarization of backscatter from hydrometeors located at short ranges from the aircraft. The variance of the Doppler velocity estimates can be well predicted from theory and were also estimated directly from the observed correlation between the H-polarized and V-polarized successive pulses. The study represents a key milestone towards the implementation of polarization diversity in Doppler space-borne radars

Hypertension, obesity and central obesity in diabetics and non diabetics in Southern Ethiopia

Diabetes mellitus coexists at a greater frequency with hypertension, obesity, central obesity, dyslipedemia and proteinuria and that markedly increases the risk of atherosclerotic disease. A study was done for a period of four months in Sidama Zone, Southern Ethiopia to compare the prevalence of atherosclerotic risk factors between diabetic and non diabetic general population. One hundred ninety nine diabetic cases were selected from two hospitals diabetic clinics and 195 non diabetics subjects were selected from urban and rural areas. The general prevalence of hypertension in the entire study population was 18.8%, with 26.1% in diabetics and 10.2% in non diabetics. Multivariate logistic regression showed that hypertension, central obesity, overweight and obesity, and ethnicity had strong association with possibility of diabetes mellitus. The reason for possible racial difference to cardiovascular risk factors and population awareness to these factors should be studied. [Ethiop. J. Health Dev. 2010;24(2):145-147

Does export dependency hurt economic development? Empirical evidence from Singapore

A rapid export growth in East Asia was once identified as a source of the sustainable economic development that the region enjoyed. However, the current global recession has turned exports from an economic virtue to a vice. There is a growing awareness that a heavy reliance on exports has caused a serious economic downturn in the region. The present paper chooses Singapore as a case study to examine the relationship between the origin of the East Asian Miracle (i.e. export dependency) and the economic growth. For this purpose, the study employs a causality test developed by Toda and Yamamoto. The empirical findings indicate that despite a negative long-run relationship between export dependency and economic growth, Singapore's heavy reliance on exports does not seem to have produced negative effects on the nation's economic growth. This is because the increase in export dependency was an effect, and not a cause, of the country's output expansion.

When it Pays to Rush: Interpreting Morphogen Gradients Prior to Steady-State

During development, morphogen gradients precisely determine the position of gene expression boundaries despite the inevitable presence of fluctuations. Recent experiments suggest that some morphogen gradients may be interpreted prior to reaching steady-state. Theoretical work has predicted that such systems will be more robust to embryo-to-embryo fluctuations. By analysing two experimentally motivated models of morphogen gradient formation, we investigate the positional precision of gene expression boundaries determined by pre-steady-state morphogen gradients in the presence of embryo-to-embryo fluctuations, internal biochemical noise and variations in the timing of morphogen measurement. Morphogens that are direct transcription factors are found to be particularly sensitive to internal noise when interpreted prior to steady-state, disadvantaging early measurement, even in the presence of large embryo-to-embryo fluctuations. Morphogens interpreted by cell-surface receptors can be measured prior to steady-state without significant decrease in positional precision provided fluctuations in the timing of measurement are small. Applying our results to experiment, we predict that Bicoid, a transcription factor morphogen in Drosophila, is unlikely to be interpreted prior to reaching steady-state. We also predict that Activin in Xenopus and Nodal in zebrafish, morphogens interpreted by cell-surface receptors, can be decoded in pre-steady-state.Comment: 18 pages, 3 figure

Forest Carbon Stocks in Woody Plants of Arba Minch Ground Water Forest and its Variations along Environmental Gradients

The role of forests in mitigating the effect of climate change depends on the carbon sequestration potential and management. This study was conducted to estimate the carbon stock and its variation along environmental gradients in Arba Minch Ground Water Forest. The data was collected from the field by measuring plants with a DBH of >5cm in quadrat plots of 10 X 20 m and the carbon stocks of each plant were analyzed by using allometric equations. From this study the mean total carbon stock density of Arba Minch Ground Water Forest was found to be 583.27 t ha-1, of which 829.12 t ha-1, 165.88 t ha-1, 1.28 t ha-1, 83.80 t ha-1 was contained in the above ground carbon, belowground carbon, litter carbon and soil organic carbon (0-30 cm depth) 0respectively. Similarly, the analysis of carbon stock variation of different carbon pools on eight different aspects of the forest area showed a significant variation with the exception of litter carbon stock and this is due to fast decomposition rate of litters and low amount of litter fall in the forest. The amount of carbon stock in above and belowground biomass, soil organic carbon and the total carbon stock was higher on the southern aspect as compared to other aspects. This study concluded that the carbon stock value of Arba Minch Ground Water Forest is large, and this will serve as a potential entry point for the engagement of the forest in REDD project.Keywords: Environmental variables; Ground Water Forest; Climate change; Biomass; Forest carbon stoc

Sampling rare switching events in biochemical networks

Bistable biochemical switches are ubiquitous in gene regulatory networks and signal transduction pathways. Their switching dynamics, however, are difficult to study directly in experiments or conventional computer simulations, because switching events are rapid, yet infrequent. We present a simulation technique that makes it possible to predict the rate and mechanism of flipping of biochemical switches. The method uses a series of interfaces in phase space between the two stable steady states of the switch to generate transition trajectories in a ratchet-like manner. We demonstrate its use by calculating the spontaneous flipping rate of a symmetric model of a genetic switch consisting of two mutually repressing genes. The rate constant can be obtained orders of magnitude more efficiently than using brute-force simulations. For this model switch, we show that the switching mechanism, and consequently the switching rate, depends crucially on whether the binding of one regulatory protein to the DNA excludes the binding of the other one. Our technique could also be used to study rare events and non-equilibrium processes in soft condensed matter systems.Comment: 9 pages, 6 figures, last page contains supplementary informatio

Forward Flux Sampling-type schemes for simulating rare events: Efficiency analysis

We analyse the efficiency of several simulation methods which we have recently proposed for calculating rate constants for rare events in stochastic dynamical systems, in or out of equilibrium. We derive analytical expressions for the computational cost of using these methods, and for the statistical error in the final estimate of the rate constant, for a given computational cost. These expressions can be used to determine which method to use for a given problem, to optimize the choice of parameters, and to evaluate the significance of the results obtained. We apply the expressions to the two-dimensional non-equilibrium rare event problem proposed by Maier and Stein. For this problem, our analysis gives accurate quantitative predictions for the computational efficiency of the three methods.Comment: 19 pages, 13 figure