740 research outputs found

    Entrainment of sediment particles by very-large-scale motions

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    Acknowledgements The study has been supported by two EPSRC/UK grants, ‘High-resolution numerical and experimental studies of turbulence-induced sediment erosion and near-bed transport’ (EP/G056404/1) and ‘Bed friction in rough-bed free-surface flows: a theoretical framework, roughness regimes, and quantification’ (EP/K041088/1). The authors are grateful to three anonymous reviewers and the Editor for constructive criticisms and helpful suggestions that improved the presentation of the material in the paper.Peer reviewedPostprin

    An Estimate of the Vibrational Frequencies of Spherical Virus Particles

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    The possible normal modes of vibration of a nearly spherical virus particle are discussed. Two simple models for the particle are treated, a liquid drop model and an elastic sphere model. Some estimates for the lowest vibrational frequency are given for each model. It is concluded that this frequency is likely to be of the order of a few GHz for particles with a radius of the order of 50 nm.Comment: 6 pages, 1 figur

    A novel experimental technique and its application to study the effects of particle density and flow submergence on bed particle saltation

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    This research was sponsored by EPSRC grant EP/G056404/1 which is greatly appreciated.Peer reviewedPublisher PD

    Quimioterapia intra-tumoral com carboplatina em carcinoma de células escamosas no plano nasal de gatos: relato de dois casos

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    Fractal Dimension and Localization of DNA Knots

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    The scaling properties of DNA knots of different complexities were studied by atomic force microscope. Following two different protocols DNA knots are adsorbed onto a mica surface in regimes of (i) strong binding, that induces a kinetic trapping of the three-dimensional (3D) configuration, and of (ii) weak binding, that permits (partial) relaxation on the surface. In (i) the gyration radius of the adsorbed DNA knot scales with the 3D Flory exponent ν0.58\nu\approx 0.58 within error. In (ii), we find ν0.66\nu\approx 0.66, a value between the 3D and 2D (ν=3/4\nu=3/4) exponents, indicating an incomplete 2D relaxation or a different polymer universality class. Compelling evidence is also presented for the localization of the knot crossings in 2D.Comment: 4 pages, 3 figure

    Tourism policy and destination marketing in developing countries: the chain of influence

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    Tourism marketers including destination marketing organisations (DMOs) and international tour operators play a pivotal role in destination marketing, especially in creating destination images. These images, apparent in tourist brochures, are designed to influence tourist decision-making and behaviour. This paper proposes the concept of a “chain of influence” in destination marketing and image-making, suggesting that the content of marketing materials is influenced by the priorities of those who design these materials, e.g. tour operators and DMOs. A content analysis of 2,000 pictures from DMO and tour operator brochures revealed synergies and divergence between these marketers. The brochure content was then compared to the South African tourism policy, concluding that the dominant factor in the chain of influence in the South African context is in fact its organic image

    Numerical study of linear and circular model DNA chains confined in a slit: metric and topological properties

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    Advanced Monte Carlo simulations are used to study the effect of nano-slit confinement on metric and topological properties of model DNA chains. We consider both linear and circularised chains with contour lengths in the 1.2--4.8 μ\mum range and slits widths spanning continuously the 50--1250nm range. The metric scaling predicted by de Gennes' blob model is shown to hold for both linear and circularised DNA up to the strongest levels of confinement. More notably, the topological properties of the circularised DNA molecules have two major differences compared to three-dimensional confinement. First, the overall knotting probability is non-monotonic for increasing confinement and can be largely enhanced or suppressed compared to the bulk case by simply varying the slit width. Secondly, the knot population consists of knots that are far simpler than for three-dimensional confinement. The results suggest that nano-slits could be used in nano-fluidic setups to produce DNA rings having simple topologies (including the unknot) or to separate heterogeneous ensembles of DNA rings by knot type.Comment: 12 pages, 10 figure
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