6 research outputs found
Salinity Measurements Collected by Fishermen Reveal a âRiver in the Seaâ Flowing Along the Eastern Coast of India
Being the only tropical ocean bounded by a continent to the north, the Indian Ocean is home to the most powerful monsoon system on Earth. Monsoonal rains and winds induce huge river discharges and strong coastal currents in the northern Bay of Bengal. To date, the paucity of salinity data has prevented a thorough description of the spreading of this freshwater into the bay. The potential impact of the salinity on cyclones and regional climate in the Bay of Bengal is, however, a strong incentive for a better description of the water cycle in this region. Since May 2005, the National Institute of Oceanography conducts a program in which fishermen collect seawater samples in knee-deep water at eight stations along the Indian coastline every 5 days. Comparison with open-ocean samples shows that this cost-effective sampling strategy is representative of offshore salinity evolution. This new dataset reveals a salinity drop exceeding 10 g kgâ1 in the northern part of the bay at the end of the summer monsoon. This freshening signal propagates southward in a narrow (~100 km wide) strip along the eastern coast of India, and reaches its southern tip after 2.5 months. Satellite-derived alongshore-current data shows that the southward propagation of this âriver in the seaâ is consistent with transport by seasonal coastal currents, while other processes are responsible for the ensuing erosion of this coastal freshening. This simple procedure of coastal seawater samples collection could further be used to monitor phytoplankton concentration, bacterial content, and isotopic composition of seawater along the Indian coastlin
Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs
: AIMS/HYPOTHESIS: Evaluation of the association of 31 common single nucleotide polymorphisms (SNPs) with fasting glucose, fasting insulin, HOMA-beta cell function (HOMA-?), HOMA-insulin resistance (HOMA-IR) and type 2 diabetes in the Indian population. METHODS: We genotyped 3,089 sib pairs recruited in the Indian Migration Study from four cities in India (Lucknow, Nagpur, Hyderabad and Bangalore) for 31 SNPs in 24 genes previously associated with type 2 diabetes in European populations. We conducted within-sib-pair analysis for type 2 diabetes and its related quantitative traits. RESULTS: The risk-allele frequencies of all the SNPs were comparable with those reported in western populations. We demonstrated significant associations of CXCR4 (rs932206), CDKAL1 (rs7756992) and TCF7L2 (rs7903146, rs12255372) with fasting glucose, with ? values of 0.007 (p?=?0.05), 0.01 (p?=?0.01), 0.007 (p?=?0.05), 0.01 (p?=?0.003) and 0.08 (p?=?0.01), respectively. Variants in NOTCH2 (rs10923931), TCF-2 (also known as HNF1B) (rs757210), ADAM30 (rs2641348) and CDKN2A/B (rs10811661) significantly predicted fasting insulin, with ? values of -0.06 (p?=?0.04), 0.05 (p?=?0.05), -0.08 (p?=?0.01) and -0.08 (p?=?0.02), respectively. For HOMA-IR, we detected associations with TCF-2, ADAM30 and CDKN2A/B, with ? values of 0.05 (p?=?0.04), -0.07 (p?=?0.03) and -0.08 (p?=?0.02), respectively. We also found significant associations of ADAM30 (??=?-0.05; p?=?0.01) and CDKN2A/B (??=?-0.05; p?=?0.03) with HOMA-?. THADA variant (rs7578597) was associated with type 2 diabetes (OR 1.5; 95% CI 1.04, 2.22; p?=?0.03). CONCLUSIONS/INTERPRETATION: We validated the association of seven established loci with intermediate traits related to type 2 diabetes in an Indian population using a design resistant to population stratification
Salinity Measurements Collected by Fishermen Reveal a âRiver in the Seaâ Flowing Along the Eastern Coast of India
International audienceBeing the only tropical ocean bounded by a continent to the north, the Indian Ocean is home to the most powerful monsoon system on Earth. Monsoonal rains and winds induce huge river discharges and strong coastal currents in the northern Bay of Bengal. To date, the paucity of salinity data has prevented a thorough description of the spreading of this freshwater into the bay. The potential impact of the salinity on cyclones and regional climate in the Bay of Bengal is, however, a strong incentive for a better description of the water cycle in this region. Since May 2005, the National Institute of Oceanography conducts a program in which fishermen collect seawater samples in knee-deep water at eight stations along the Indian coastline every 5 days. Comparison with open-ocean samples shows that this cost-effective sampling strategy is representative of offshore salinity evolution. This new dataset reveals a salinity drop exceeding 10 g kg-1 in the northern part of the bay at the end of the summer monsoon. This freshening signal propagates southward in a narrow (~100 km wide) strip along the eastern coast of India, and reaches its southern tip after 2.5 months. Satellite-derived alongshore-current data shows that the southward propagation of this âriver in the seaâ is consistent with transport by seasonal coastal currents, while other processes are responsible for the ensuing erosion of this coastal freshening. This simple procedure of coastal seawater samples collection could further be used to monitor phytoplankton concentration, bacterial content, and isotopic composition of seawater along the Indian coastline