Computability on quasi-Polish spaces

International audienceWe investigate the effectivizations of several equivalent definitions of quasi-Polish spaces and study which characterizations hold effectively. Being a computable effectively open image of the Baire space is a robust notion that admits several characterizations. We show that some natural effectivizations of quasi-metric spaces are strictly stronger

Specific features of Bazhenov suite sediments in south-eastern Nurolsk sedimentary basin (Tomsk Oblast)

The specific sediment features in Georgiev (J[3]kmgr), Bazhenov (J3vbg) and Kulomzin (K1bkl) suites, exposed by drilling in the S-E Nurolsk depression (Tomsk Oblast), were defined and described via petrographic, X-ray diffraction and fluorescence-microscopy analysis methods. The classification of agrillites was identified, the structure-texture features, composition, voids and bitumen types and their distribution were determined. It was defined that Bazhenov suite argillites are characteristic of fine-dispersion, high biogenic silica content and scattered organic matter, enriched multi-composite syngenetic bitumen (from light to resin-asphaltine), as well as fractured surface where the migration of light bitumen occurs

The role of herpes virus infection in development of arrhythmias in children

ECG' peculiarities and titers of anticardial antibodies (ACAB) were studied in 44 children with herpes virus infection: 63% of patients were infected by herpes virus type IV, V, VI; the rest ones - herpes virus type I,II in addition. ECG has revealed dysfunction of sinus node, conductive disturbances and changes of repolarization in 1/3 of children, 20% of patients has signs of myocardial electric instability. Part of children has increased titers of ACAB to conductive system and cardiomyocytes

Black-hole concept of a point-like nucleus with supercritical charge

The Dirac equation for an electron in the central Coulomb field of a point-like nucleus with the charge greater than 137 is considered. This singular problem, to which the fall-down onto the centre is inherent, is addressed using a new approach, based on a black-hole concept of the singular centre and capable of producing cut-off-free results. To this end the Dirac equation is presented as a generalized eigenvalue boundary problem of a self-adjoint operator. The eigenfunctions make complete sets, orthogonal with a singular measure, and describe particles, asymptotically free and delta-function-normalizable both at infinity and near the singular centre $r=0$. The barrier transmission coefficient for these particles responsible for the effects of electron absorption and spontaneous electron-positron pair production is found analytically as a function of electron energy and charge of the nucleus. The singular threshold behaviour of the corresponding amplitudes substitutes for the resonance behaviour, typical of the conventional theory, which appeals to a finite-size nucleus.Comment: 22 pages, 5 figures, LATEX requires IOPAR

Recent Advances in Σ-definability over Continuous Data Types

The purpose of this paper is to survey our recent research in computability and definability over continuous data types such as the real numbers, real-valued functions and functionals. We investigate the expressive power and algorithmic properties of the language of Sigma-formulas intended to represent computability over the real numbers. In order to adequately represent computability we extend the reals by the structure of hereditarily finite sets. In this setting it is crucial to consider the real numbers without equality since the equality test is undecidable over the reals. We prove Engeler's Lemma for Sigma-definability over the reals without the equality test which relates Sigma-definability with definability in the constructive infinitary language L_{omega_1 omega}. Thus, a relation over the real numbers is Sigma-definable if and only if it is definable by a disjunction of a recursively enumerable set of quantifier free formulas. This result reveals computational aspects of Sigma-definability and also gives topological characterisation of Sigma-definable relations over the reals without the equality test. We also illustrate how computability over the real numbers can be expressed in the language of Sigma-formulas

Assessment of polymorbidity, antihypertensive therapy, renal function and electrolyte disorders in hospitalized cardiac patients

The purpose of the study is to evaluate the differences in kidney function and the state of electrolyte metabolism.Цель исследования – оценить различия функций почек и состояния электролитного обмена

Effect of exogenous factors on somatic health and autonomic nervous regulation in children and young people

Монографія присвячена аналізу впливу зовнішних чинників та особливостей способу життя на стан здоров’я, зміни автономної нервової регуляції та стан серцево-судинної системи, які здатні призводити до порушень стану здоров’я у дітей та юнацтва

Clinical and anamnestic and biological candidates for participation in the mechanisms of genital prolapse formation in women

Introduction. The article presents an overview of the results of modern evidence-based scientific research on the mechanisms of formation of genital prolapse as one of the fundamental causes of pelvic floor muscle insufficiency in women. A systematic analysis of the current literature data on the involvement of clinical, anamnestic and pathogenetic motives in the development of pelvic organ prolapse in women was carried out. Objective: to expand the understanding of the role of anamnestic and biological factors in the pathogenesis of genital prolapse in womenЦель исследования: расширить представление о роли анамнестических и биологических факторов в патогенезе пролапса гениталий у женщи

Комбинированное лечение больных раком прямой кишки с использованием программы полирадиомодификации в сочетании с короткими курсами неоадъювантной лучевой терапии

Objective: to improve the outcomes of combination treatment of patients with rectal cancer using polyradiomodification and short courses of neoadjuvant radiotheragy.Materials and methods. A total of 905patients were included into this retrospective study based on the data retrieved from a prospective database. Of them, 241 patients underwent combination treatment with polyradiomodification (CT + PRM); 271 patients underwent combination treatment with preoperative radiotherapy alone (CT); 393patients underwent surgical treatment only (ST). Combination treatment with polyradiomodification included a course of radiotherapy with a total dose of 25 Gy delivered in 5 fractions (5 Gy each), rectal administration of biopolymer composition containing metronidazole at a dose of 10 g/m2 (5-h exposure in the rectum on days 3 and 5), and chemotherapy with capecitabine at a dose of 2 g/m2 on days 1—14 followed by surgery within the next 4—6 weeks. We analyzed the incidence of postoperative complications, 5-year relapse-free survival, and frequency of relapses.Results. The incidence of grade IIIB postoperative complications was significantly lower in patients who underwent combination treatment with polyradiomodification than in those who had surgery only (p = 0.0023) and those who had combination therapy without polyradiomodification (p = 0.0003). The 5-year relapse-free survival rate was 80.5 % in the group of CT + PRM compared to 64.9 % in the group of CT (p = 0.00315) and 60.1 % in the group of ST (p = 0.000001). The frequency of relapses was 0.4 %, 8.5 % (p = 0.00001), and 13.7 % (p = 0.00001) in the groups CT + PRM, CT, and ST respectively. There were no significant differences in the incidence of distant metastasis between the groups.Conclusions. The developed variant of combination treatment with polyradiomodification did not increase the number of complications and ensured better relapse-free survival due to improved locoregional control.Цель исследования — улучшить результаты комбинированного метода лечения больных раком прямой кишки с использованием программы полирадиомодификации в сочетании с короткими курсами неоадъювантной лучевой терапии.Материалы и методы. В ретроспективное исследование, основанное на данных проспективно заполняемой базы данных, включено 905 больных, из которых у 241 проведено комбинированное лечение с применением программы полирадиомодификации, у 271 пациента ранее проведено комбинированное лечение с использованием только предоперационной лучевой терапии в монорежиме, и у 393 — только хирургическое лечение. Комбинированное лечение с применением программы полирадиомодификации включало проведение курса лучевой терапии в разовой очаговой дозе 5 Гр в течение 5 дней до суммарной очаговой дозы 25 Гр, внутриректальной сверхвысокочастотной гипертермии в дни 3 и 5, введение биополимерной композиции, содержащей метронидазол в дозе 10 г/м2, с экспозицией ее в прямой кишке в течение 5 ч в дни 3 и 5, а также проведение химиотерапии капецитабином в дозе 2 г/м2 в дни 1—14 с последующим оперативным вмешательством в сроки от 4 до 6 нед. Анализировали частоту послеоперационных осложнений, 5-летнюю безрецидивную выживаемость, частоту рецидивов.Результаты. Частота послеоперационных осложнений IIIB степени тяжести в группе комбинированного лечения с применением программы полирадиомодификации была ниже по сравнению с группой хирургического лечения (р = 0,0023) и группой комбинированного лечения без применения программы полирадиомодификации (р = 0,0003). Пятилетняя безрецидивная выживаемость в группе комбинированного лечения с применением программы полирадиомодификации составила 80,5 % по сравнению с 64,9 % в группе комбинированного лечения без использования полирадиомодификации (р = 0,00315) и 60,1 % в группе хирургического лечения (р = 0,000001). Частота рецидивов составила 0,4 %, 8,5 % (р = 0,00001) и 13,7 % (р = 0,00001) соответственно. Частота отдаленного метастазирования достоверно не различалась между группами.Выводы. Созданный вариант комбинированного лечения с применением программы полирадиомодификации не приводит к увеличению общего количества осложнений и в рамках проведенного ретроспективного исследования обеспечивает более высокие показатели безрецидивной выживаемости за счет усиления локорегионарного контроля