203 research outputs found
Improved texture of breast meat after a short finishing feeding period of broilers in an organic free-range system
In order to develop an organic broiler product with high ethical value, high meat quality and based on locally produced feed, we tested if a long period without high quality protein feed followed by a finishing period with a high quality protein ration would affect the meat quality. Two genotypes were included in the experiment (The Hubbard breed âJA757â and the Sasso breed âT851â), and only female broilers were included. The chickens were raised in groups in a free range system with more than 10 square meters per chicken covered with grass and herbs. The chickens were offered free access to either an optimized organic concentrate ration (HP) or an organic ration based on locally produced ingredients (peas, rapeseed, lupine, wheat and oat) (LP). The broilers were slaughtered at 90 days (HP) or 118 days (LP). At 90 days the LP broilers were allocated to the high quality protein ration (HP) for either four weeks (LP4) or two weeks (LP2) before slaughter. At slaughter the JA757 HP broilers were the heaviest (2827 g), and the JA757 LP broilers were not able to catch up after either 2 or 4 weeks finishing feeding with the HP ration (2248 g and 2292 g, respectively). This was different for the T851 genotype where there was no difference in slaughter weight between the T851 HP and LP2 and LP4 (average 1592 g). A sensory panel evaluated the sensory quality of the breast meat and found less firmness and fibrousness, lower chewing time and more tenderness in both genotypes offered high quality protein feed in the finishing feeding for 2 weeks in comparison with the 4 weeks finishing feeding, with the HP in between. This pattern is reflected in the daily gains the last two weeks before slaughter and suggests a positive linkage between daily gain before slaughter and tenderness post mortem
Ăkologiske kyllinger pĂĽ urter - vejen til høj dyrevelfĂŚrd (D.5.4)
Slagtekyllinger vokser hurtigt, hvilket er en egenskab opnüet gennem mange ürs avl og foderoptimering. Dette resulterer ofte i benproblemer og et lavt aktivitetsniveau, hvilket øger risikoen for sür og svidninger pü fødderne. Ved brug af nye kyllingetyper med langsommere vÌkst og Ìndret fodringsstrategi forventes bedre velfÌrd, kyllinge-kød med ny spisekvalitet og bedre udnyttelse af føde fra udearealet
Urea production and turnover following the addition of AMP, CMP, RNA and a protein mixture to a marine sediment
The potential of adenosine 5â˛-monophosphate (AMP), cytidine 5â˛-monophosphate (CMP), 16S ribosomal RNA, and a protein (bovine serum albumin) to serve as substrates for bacterial urea production was evaluated in a defaunated, anoxic marine sediment. AMP, CMP and RNA stimulated urea production and urea turnover, but CMP to a lesser degree than AMP and RNA. The increase in urea production and turnover rates took place immediately after AMP, CMP, and RNA were added to the sediment. The rapid response in urea production and turnover rates suggests that the necessary uptake mechanisms and enzymes to utilize the substrates were present constitutively. Addition of the protein mixture did not result in any measurable changes in the urea pool size, urea turnover rate, or urea production rate during the 165 h of incubation. However, an increased and continuous net NH4+ production in the protein-amended sediment relative to the control sediment indicated that the added protein mixture was accessible for bacterial degradation. The results showed that purines and pyrimidines were substrates for the bacterial urea production in the marine sediment, whereas protein was not important for urea production
Measuring the capability to raise revenue process and output dimensions and their application to the Zambia revenue authority
The worldwide diffusion of the good governance agenda and new public management has triggered a renewed focus on state capability and, more specifically, on the capability to raise revenue in developing countries. However, the analytical tools for a comprehensive understanding of the capability to raise revenue remain underdeveloped. This article aims at filling this gap and presents a model consisting of the three process dimensions âinformation collection and processingâ, âmerit orientationâ and âadministrative accountabilityâ. âRevenue performanceâ constitutes the fourth capability dimension which assesses tax administrationâs output. This model is applied to the case of the Zambia Revenue Authority. The dimensions prove to be valuable not only for assessing the how much but also the how of collecting taxes. They can be a useful tool for future comparative analyses of tax administrationsâ capabilities in developing countries.Die weltweite Verbreitung der Good-Governance- und New-Public-Management-Konzepte hat zu einer zunehmenden Konzentration auf staatliche Leistungsfähigkeit und, im Besonderen, auf die Leistungsfähigkeit der Steuererhebung in Entwicklungsländern gefĂźhrt. Allerdings bleiben die analytischen Werkzeuge fĂźr ein umfassendes Verständnis von Leistungsfähigkeit unterentwickelt. Dieser Artikel stellt hierfĂźr ein Modell vor, das die drei Prozess-Dimensionen âSammeln und Verarbeiten von Informationenâ, âLeistungsorientierung der Mitarbeiterâ und âVerantwortlichkeit der Verwaltungâ beinhaltet. âEinnahmeperformanzâ ist die vierte Dimension und erfasst den Output der Steuerverwaltung. Das mehrdimensionale Modell wird fĂźr die Analyse der Leistungsfähigkeit der SteuerbehĂśrde Zambias (Zambia Revenue Authority) genutzt. Es erweist sich nicht nur fĂźr die Untersuchung des Wieviel, sondern auch des Wie des Erhebens von Steuern als wertvoll. Die vier Dimensionen kĂśnnen in Zukunft zur umfassenden und vergleichenden Analyse der Leistungsfähigkeit verschiedener Steuerverwaltungen in Entwicklungsländern genutzt werden
Transcutaneous spinal direct current stimulation increases corticospinal transmission and enhances voluntary motor output in humans
Optimization of motor performance is of importance in daily life, in relation to recovery following injury as well as for elite sports performance. The present study investigated whether transcutaneous spinal direct current stimulation (tsDCS) may enhance voluntary ballistic activation of ankle muscles and descending activation of spinal motor neurons in ableâbodied adults. Fortyâone adults (21 men; 24.0 Âą 3.2 years) participated in the study. The effect of tsDCS on ballistic motor performance and plantar flexor muscle activation was assessed in a doubleâblinded shamâcontrolled crossâover experiment. In separate experiments, the underlying changes in excitability of corticospinal and spinal pathways were probed by evaluating soleus (SOL) motor evoked potentials (MEPs) following singleâpulse transcranial magnetic stimulation (TMS) over the primary motor cortex, SOL Hâreflexes elicited by tibial nerve stimulation and TMSâconditioning of SOL Hâreflexes. Measures were obtained before and after cathodal tsDCS over the thoracic spine (T11âT12) for 10 min at 2.5 mA. We found that cathodal tsDCS transiently facilitated peak acceleration in the ballistic motor task compared to sham tsDCS. Following tsDCS, SOL MEPs were increased without changes in Hâreflex amplitudes. The shortâlatency facilitation of the Hâreflex by subthreshold TMS, which is assumed to be mediated by the fast conducting monosynaptic corticomotoneuronal pathway, was also enhanced by tsDCS. We argue that tsDCS briefly facilitates voluntary motor output by increasing descending drive from corticospinal neurones to spinal plantar flexor motor neurons. tsDCS can thus transiently promote withinâsession CNS function and voluntary motor output and holds potential as a technique in the rehabilitation of motor function following central nervous lesions
Angiopoietin-2/-1 ratios and MMP-3 levels as an early warning sign for the presence of giant cell arteritis in patients with polymyalgia rheumatica
BACKGROUND: Diagnosing patients with giant cell arteritis (GCA) remains difficult. Due to its non-specific symptoms, it is challenging to identify GCA in patients presenting with symptoms of polymyalgia rheumatica (PMR), which is a more common disease. Also, commonly used acute-phase markers CRP and ESR fail to discriminate GCA patients from PMR and (infectious) mimicry patients. Therefore, we investigated biomarkers reflecting vessel wall inflammation for their utility in the accurate diagnosis of GCA in two international cohorts. METHODS: Treatment-naĂŻve GCA patients participated in the Aarhus AGP cohort (N = 52) and the Groningen GPS cohort (N = 48). The AGP and GPS biomarker levels and symptoms were compared to patients presenting phenotypically as isolated PMR, infectious mimicry controls and healthy controls (HCs). Serum/plasma levels of 12 biomarkers were measured by ELISA or Luminex. RESULTS: In both the AGP and the GPS cohort, we found that weight loss, elevated erythrocyte sedimentation rate (ESR) and higher angiopoietin-2/-1 ratios but lower matrix metalloproteinase (MMP)-3 levels identify concomitant GCA in PMR patients. In addition, we confirmed that elevated platelet counts are characteristic of GCA but not of GCA mimicry controls and that low MMP-3 and proteinase 3 (PR3) levels may help to discriminate GCA from infections. CONCLUSION: This study, performed in two independent international cohorts, consistently shows the potential of angiopoietin-2/-1 ratios and MMP-3 levels to identify GCA in patients presenting with PMR. These biomarkers may be used to select which PMR patients require further diagnostic workup. Platelet counts may be used to discriminate GCA from GCA look-alike patients. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13075-022-02754-5
Evolutionary impact assessment: accounting for evolutionary consequences of fishing in an ecosystem approach to fisheries management
Managing fisheries resources to maintain healthy ecosystems is one of the main goals of the ecosystem approach to fisheries (EAF). while the number of international treaties call for the implementation of EAF, there are still gaps in the underlying methodology. One aspect that has received substantial scientific attention recently in fisheries-induced evolution (FIE). Increasing evidence indicates that intensive fishing has the potential to exert strong directional selection on life-history traits, behavior, physiology, and morphology of exploited fish. Of particular concern is that reversing evolutionary responses to fishing can be much more difficult than reversing demographic or phenotypically plastic responses. Furthermore, like climate change, multiple agents cause fisheries-induced evolution with effects accumulating over time. Consequently, FIE may alter then utility derived from fish stocks, which in turn can modify the monetary value living aquatic resources provide to society. Quantifying and predicting the evolutionary effects of fishing is therefore important for both ecological and economic reasons, An important reason this is not happening is the lack of an appropriate assessment framework. We therefor describe the evolutionary impact assessment (EvoIA) as a structured approach for assessing the evolutionary outcomes of alternative management options. EvoIA can contribute to the ecosystem approach to fisheries management by clarifying how evolution may alter stock properties and ecological relations, support the precautionary approach to fisheries management by addressing a previously overlooked source of uncertainty and risk, and thus contribute to sustainable fisheries
Measuring the Capability to Raise Revenue: Process and Output Dimensions and Their Application to the Zambia Revenue Authority
Can fisheries-induced evolution shift reference points for fisheries management?
Heino, M., Baulier, L., Boukal, D. S., Ernande, B., Johnston, F. D., Mollet, F. M., Pardoe, H., Therkildsen, N. O., Uusi-Heikkilä, S., Vainikka, A., Arlinghaus, R., Dankel, D. J., Dunlop, E. S., Eikeset, A. M., Enberg, K., Engelhard G. H., Jørgensen, C., Laugen, A. T., Matsumura, S., NusslĂŠ, S., Urbach, D., Whitlock, R., Rijnsdorp, A. D., and Dieckmann, U. 2013. Can fisheries-induced evolution shift reference points for fisheries management? - ICES Journal of Marine Science, 70: 707-721. Biological reference points are important tools for fisheries management. Reference points are not static, but may change when a population's environment or the population itself changes. Fisheries-induced evolution is one mechanism that can alter population characteristics, leading to "shiftingâ reference points by modifying the underlying biological processes or by changing the perception of a fishery system. The former causes changes in "trueâ reference points, whereas the latter is caused by changes in the yardsticks used to quantify a system's status. Unaccounted shifts of either kind imply that reference points gradually lose their intended meaning. This can lead to increased precaution, which is safe, but potentially costly. Shifts can also occur in more perilous directions, such that actual risks are greater than anticipated. Our qualitative analysis suggests that all commonly used reference points are susceptible to shifting through fisheries-induced evolution, including the limit and "precautionaryâ reference points for spawning-stock biomass, Blim and Bpa, and the target reference point for fishing mortality, F0.1. Our findings call for increased awareness of fisheries-induced changes and highlight the value of always basing reference points on adequately updated information, to capture all changes in the biological processes that drive fish population dynamic
Evolutionary impact assessment: accounting for evolutionary consequences of fishing in an ecosystem approach to fisheries management
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