524 research outputs found

    Application Of Principles Of Total Quality Management (TQM) In Teacher Education Institutions

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    The indomitable spirit of higher education paves the way for the growth of a nation in the political, economic, social, intellectual and spiritual dimensions. Teacher education is one of the areas in higher education which trains student-teachers in pedagogy, which in turn helps them to train the young minds of educational institutions. The “Fate of the nation is decided in the classroom,” is a remark made by the Education Commission of India. Such classrooms are created by committed and dedicated teachers. These teachers are trained in teacher education institutions. Teacher education institutions should maintain quality to ensure the academic excellence of trainees who come into the teaching profession. Quality is a comparative standard prescribed for those institutions that are on the quest for output brilliance. Quality assurance in teacher education reflects on the high profile of the institution and the competency of student-teachers. The present study on the application of principals of TQM in teacher education institutions in India has exposed the tangibility of institutions in the perception of teachers based on eleven quality indicators, such as principal as leader, teacher quality, linkage and interface, students, co-curricular activities, teaching, office management, relationships, material resources, examinations and job satisfaction. A total of nine colleges of education was selected to collect data. The exploratory technique under the survey method of research design was used for the study. A tool - ‘Teacher Institutional Profile’ (TIP) - was constructed, standardized and used for data collection. Quantitative and qualitative analyses were made for finding and interpreting results. The findings focus on the strong and weak areas of various teacher education institutions according to the quality indicators. The study recommends further strengthening of quality indicators, which are already strong, and the revamping of weaker quality indicators. It is also recommended that institutions should adhere to the quality standards set by national and international assessment and accreditation bodies. In conclusion, the global scenario expects skilled teachers to produce students with a versatile personality for which teacher education should be strengthened

    ANTIDIABETIC AND ANTIOXIDANT EFFICACY OF BONE MARROW STEM CELLS ON STZE-INDUCED MALE ALBINO WISTAR RATS

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    Diabetes mellitus is a multi-metabolic disorder that influences more than 348 million people worldwide. A key goal of diabetes treatment is to prevent complications because over time, diabetes can damage the heart, blood vessels, eyes, kidneys, and nerves. Consequently there is an incredible need to develop new and successful therapies for treating diabetic complications early before it causes irreparable tissue damage. Bone marrow derived mesenchymal stem cells (BMSCs) offer significant benefits for clinical application, because they can be easily harvested and, when autologous transplanted, there is no immunological rejection. Moreover, BMSCs can differentiate into a wide variety of cell types. Here, we focused on bone marrow-derived mesenchymal stem cells (MSCs) can transdifferentiate into insulin-producing cells (IPC) under defined conditions  and normalize the glucose level of streptozotocin (STZ)- induced diabetic rats.The main objective of  the study was To evaluate the antidiabetic activity of the Dental pulp cells in Streptozotocin (STZ)-induced diabetic Wistar albino rats.To calculate the biochemical estimation of both normal and treated groups.To study the effects of dental pulp cells on morphological characterization of normal and treated groups. Streptozotocin.,Wistar albino rat.,Insulin.,stem cell.,fibroblas

    FORMULATION AND EVALUATION OF GASTRORETENTIVE MICROBALLOONS OF ACEBROPHYLLINE FOR THE TREATMENT OF BRONCHIAL ASTHMA

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    Objective: Gastroretentive dosage forms are an approach for prolonged and predictable drug delivery in the upper gastrointestinal tract to controlthe gastric residence time. Microballoons are considered as one of the most promising buoyant drug delivery systems as they possess the advantagesof both multiple-unit systems and good floating properties. Acebrophylline is a xanthine derivative with potent bronchodilator, mucosecretolytic, andanti-inflammatory property. It is used to treat bronchial asthma and chronic obstructive pulmonary diseases.Methods: Microballoons of acebrophylline were prepared by emulsion solvent diffusion method using hydroxypropyl methylcellulose (HPMC) andethyl cellulose (EC) as polymer. The microballoons were evaluated with their micromeritic properties, particle size, tapped density, compressibilityindex, angle of repose, percentage yield, in vitro buoyancy, entrapment efficiency, drug-polymer compatibility, scanning electron microscopy (SEM),and drug release kinetics.Results: The mean particle size of the microballoons formulation MB1 to MB6 containing HPMC and EC was in the range between 226±16 and 577±10,respectively. The mean particle size of microballoons was found to increase with increasing polymer concentration. The micromeritic properties werefound be good, and SEM confirmed their hollow structure with smooth and dense which helped to prolong floating to increase residence time instomach. The in vitro drug release studies showed controlled release of acebrophylline microballoons in the simulated gastric fluid more than 12 hrs.Conclusions: The results showed that the prepared floating microballoons of acebrophylline prove to be potential multiple-unit delivery devicesadaptable for safe and effective sustained drug delivery.Keywords: Microballoons, Acebrophylline, Bronchial asthma, Hydroxypropyl methylcellulose, Ethyl cellulose

    1-[2-(2,4-Dinitro­benzyl­ideneamino)phen­yl]-3-phenyl­thio­urea

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    In the title compound, C20H15N5O4S, the central benzene ring makes dihedral angles of 59.5 (1) and 51.7 (1)°, respectively, with the terminal phenyl and benzene rings. The mol­ecular structure exhibits weak intra­molecular N—H⋯N and C—H⋯S inter­actions. In the crystal structure, mol­ecules are linked by weak inter­molecular N—H⋯S and C—H⋯O inter­actions, forming a chain along [11]

    Determination of Intrinsic Ferroelectric Polarization in Orthorhombic Manganites with E-type Spin Order

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    By directly measuring electrical hysteresis loops using the Positive-Up Negative-Down (PUND) method, we accurately determined the remanent ferroelectric polarization Pr of orthorhombic RMnO3 (R = Ho, Tm, Yb, and Lu) compounds below their E-type spin ordering temperatures. We found that LuMnO3 has the largest Pr of 0.17 uC/cm^2 at 6 K in the series, indicating that its single-crystal form can produce a Pr of at least 0.6 \muuC/cm^2 at 0 K. Furthermore, at a fixed temperature, Pr decreases systematically with increasing rare earth ion radius from R = Lu to Ho, exhibiting a strong correlation with the variations in the in-plane Mn-O-Mn bond angle and Mn-O distances. Our experimental results suggest that the contribution of the Mn t2g orbitals dominates the ferroelectric polarization.Comment: 16 pages, 4 figure

    Patient advice regarding participation in sport in children with disorders of cerebrospinal fluid (CSF) circulation: a national survey of British paediatric neurosurgeons

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    Background Management of children with disorders of cerebrospinal fluid (CSF) circulation is a common aspect of paediatric neurosurgical practice. Sport and physical activity play an integral role in the lives of patients in this age group. However, there is little evidence to support the dissemination of appropriate advice to children regarding such activities. The aim of this study was to evaluate the perspectives of clinicians across the UK regarding the participation of children with disorders of CSF circulation in sports. Methods Questionnaires were distributed to Consultant Paediatric Neurosurgeons practising across the UK via the Society of British Neurological Surgeons (SBNS). Five different patient scenarios were supplied, and participants were asked to choose whether they would advise participation in the following sports: Taekwondo, rugby, skiing, and football. Results An overall response rate of 66.7% (36 out of 54 paediatric neurosurgeons) was achieved. The following percentages of clinicians advocated football, rugby, Taekwondo, and skiing across all scenarios: 96%, 75%, 77%, and 97%, respectively. The majority of responders (91.2%) relied on personal experience when providing advice, whilst 50% used available literature and 19.4% used available guidelines. Conclusions There is a paucity of evidence in the literature to support the dissemination of appropriate advice to children with disorders of CSF circulation regarding participation in sports. Our findings demonstrate that the majority of clinicians rely on personal experience to make such decisions, emphasizing the necessity of larger scale studies to inform evidence-based guidelines

    Response of rice (Oryza sativa L.) productivity and nutrient uptake to nitrogen and boron fertilization in Typic Ustifluvents soil

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    Nitrogen and boron are necessary for the metabolic activities of rice for its growth. With this perspective, a field experiment was conducted in farmer’s field during 2020 at Kuttalam, Mayladuthurai district, Tamilnadu in sandy clay loam(Padugai Series – TypicUstifluvents) to predict the response of rice (Oryza sativa) to different levels of nitrogen(N) and boron (B) application. The treatments consisted of Factor A- Nitrogen levels, 0, 75, 150, 225 kg ha-1 and Factor B- Boron levels 0, 1.5, 3.0 kg ha-1. Fifteen treatments were conducted in a Factorial randomised block (FRBD) design with three replications.  The test crop was rice with a variety ADT 46.    Concerning nitrogen alone, the highest grain (5344 kg ha-1) and straw yield was recorded in N3(225 kg ha-1). Among the boron levels tested, the highest grain (4695 kg ha-1) and straw yield (6509 kg ha-1) was registered in B1 (1.5 kg ha-1) in rice. The highest total nutrient uptake viz., N(88.2 kg ha-1), P(30.5 kg ha-1), K(105.0 kg ha-1) and B(172mg kg-1)  were recorded in N3B1. Among the N alone, the highest total nutrient uptake viz., N(78.1kg ha-1, P(26.3kg ha-1), K (95.8 kg ha-1) and B(156.6 mg kg-1) in N3. Concerning B alone, the highest nutrient uptake viz., N(60.5, kg ha-1) , P(17.8kg ha-1) K(74.9 kg ha-1) and B(112.1mg kg-1) were registered in B1 over other B levels. The highest grain (5631 kg ha-1) was recorded in N3B1 (225 kg N ha-1 and 1.5kg B ha-1) than other interactions. The study concluded that applying nitrogen and boron is required to achieve the maximum yield of rice in sandy clay loam soil

    Combustion and Emission Analysis of Mahua and Jujube Biodiesel Blends as Fuel in a CI Engine

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    This present study on biodiesel blends shows the performance, emission and combustion characteristics of the DI diesel engine, which is been run independently on direct diesel fuel, 20% blending of zizipus jujbe methyl ester (ZJME20), and 20% blending of mahua methyl ester (MME20) with diesel. In this study, the tested fuels were obtained by catalytic transesterification process. Based on the experimental results, MME20 is favorable for less HC, CO, and smoke density than diesel and ZJME20. Based on the brake thermal efficiency and specific fuel consumption, MME20 is better when compared with ZJME20. The result also showed momentous improvement in the heat releasing rate due to the better performance characteristic of MME20
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