2,770 research outputs found

    Electronic energy spectra and wave functions on the square Fibonacci tiling

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    We study the electronic energy spectra and wave functions on the square Fibonacci tiling, using an off-diagonal tight-binding model, in order to determine the exact nature of the transitions between different spectral behaviors, as well as the scaling of the total bandwidth as it becomes finite. The macroscopic degeneracy of certain energy values in the spectrum is invoked as a possible mechanism for the emergence of extended electronic Bloch wave functions as the dimension changes from one to two

    Field theoretic calculation of scalar turbulence

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    The cascade rate of passive scalar and Bachelor's constant in scalar turbulence are calculated using the flux formula. This calculation is done to first order in perturbation series. Batchelor's constant in three dimension is found to be approximately 1.25. In higher dimension, the constant increases as d1/3d^{1/3}.Comment: RevTex4, publ. in Int. J. Mod. Phy. B, v.15, p.3419, 200

    Addition of benzodiazepines to selective serotonin reuptake inhibitors to optimize treatment of depression: a hospital based study

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    Background: Selective serotonin reuptake inhibitors ameliorate depression and anxiety slowly and in fact increase anxiety or insomnia initially. Addition of clonazepam to escitalopram improves response: thereby improving symptoms associated with depression, reducing side-effects and alleviating core depressive symptoms. The aim of study was to assess the benefits of adding benzodiazepines in management of depression.Methods: It was an open label prospective study of 8 weeks of escitalopram group versus escitalopram with benzodiazepine group in moderate to severe depression. 51 subjects who gave written informed consent and were fulfilling the inclusion and exclusion criteria were included in the study and grouped into escitalopram alone or escitalopram with benzodiazepines.Results: In the present study nearly 60% of the patients were prescribed clonazepam. Though combined group with benzodiazepines had faster onset of action in controlling depressive symptoms than escitalopram group alone at 4 weeks of treatment, there was no significant difference in the pattern of reduction of MADRS score in both the groups at 8 weeks of follow up.Conclusions: Augmenting benzodiazepines to antidepressants are more effective in management of depression associated anxiety and sleep disturbances initially till SSRIs start action

    A methodology for solving single-model, stochastic assembly line balancing problem

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    Cataloged from PDF version of article.In this paper, a methodology is developed to solve the single-model, stochastic assembly line balancing problem for the objective of minimizing the total labor cost and the expected incompletion cost arising from tasks not completed within the prescribed cycle time. The methodology is based on determining an initial DP based solution and its improvement using a branch-and-bound procedure which uses an approximate solution instead of a lower bound for fathoming nodes. Detailed experimentation shows the superiority of this method over the most promising one from the literature. # 1999 Elsevier Science Ltd. All rights reserved

    Mouth Image Based Person Authentication Using DWLSTM and GRU

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    Recently several classification methods were introduced to solve mouth based biometric authentication systems. The results of previous investigations into mouth prints are insufficient and produce lesser authentication results. This is mainly due to the difficulties that accompany any analysis of the mouths: mouths are very flexible and pliable, and successive mouth print impressions even those obtained from the same person may significantly differ from one other. The existing machine learning methods, may not achieve higher performance and only few methods are available using deep learning for mouth biometric authentication. The use of deep learning based mouth biometrics authentication gives higher results than usual machine learning methods. The proposed mouth based biometric authentication (MBBA) system is rigorously examined with real world data and challenges with the purpose that could be expected on mouth-based solution deployed on a mobile device. The proposed system has three major steps such as (1) database collection, (2) creating model for authentication, (3) performance evaluation. The database is collected from Annamalai University deep learning laboratory which consists of 5000 video frames belongs to 10 persons. The person authentication model is created using divergence weight long short term memory (DWLSTM) and gated recurrent unit (GRU) to capture the temporal relationship in mouth images of a person. The existing and proposed methods are implemented via the Anaconda with Jupyter notebook. Finally the results of the proposed model are compared against existing methods such as support vector machine (SVM), and Probabilistic Neural Network (PNN) with respect to metrics like precision, recall, F1-score, and accuracy of mouth

    Answer Set Programming for Non-Stationary Markov Decision Processes

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    Non-stationary domains, where unforeseen changes happen, present a challenge for agents to find an optimal policy for a sequential decision making problem. This work investigates a solution to this problem that combines Markov Decision Processes (MDP) and Reinforcement Learning (RL) with Answer Set Programming (ASP) in a method we call ASP(RL). In this method, Answer Set Programming is used to find the possible trajectories of an MDP, from where Reinforcement Learning is applied to learn the optimal policy of the problem. Results show that ASP(RL) is capable of efficiently finding the optimal solution of an MDP representing non-stationary domains

    Small Molecule Recognition of c-Src via the Imatinib-Binding Conformation

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    SummaryThe cancer drug, Imatinib, is a selective Abl kinase inhibitor that does not inhibit the closely related kinase c-Src. This one drug and its ability to selectively inhibit Abl over c-Src has been a guiding principle in virtually all kinase drug discovery efforts in the last 15 years. A prominent hypothesis explaining the selectivity of Imatinib is that Abl has an intrinsic ability to adopt an inactive conformation (termed DFG-out), whereas c-Src appears to pay a high intrinsic energetic penalty for adopting this conformation, effectively excluding Imatinib from its ATP pocket. This explanation of the difference in binding affinity of Imatinib for Abl versus c-Src makes the striking prediction that it would not be possible to design an inhibitor that binds to the DFG-out conformation of c-Src with high affinity. We report the discovery of a series of such inhibitors. We use structure-activity relationships and X-ray crystallography to confirm our findings. These studies suggest that small molecules are capable of inducing the generally unfavorable DFG-out conformation in c-Src. Structural comparison between c-Src in complex with these inhibitors allows us to speculate on the differential selectivity of Imatinib for c-Src and Abl

    New bounds on the neutrino magnetic moment from the plasma induced neutrino chirality flip in a supernova

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    The neutrino chirality-flip process under the conditions of the supernova core is investigated in detail with the plasma polarization effects in the photon propagator taken into account, in a more consistent way than in earlier publications. It is shown in part that the contribution of the proton fraction of plasma is essential. New upper bounds on the neutrino magnetic moment are obtained: mu_nu < (0.5 - 1.1) 10^{-12} mu_B from the limit on the supernova core luminosity for nu_R emission, and mu_nu < (0.4 - 0.6) 10^{-12} mu_B from the limit on the averaged time of the neutrino spin-flip. The best upper bound on the neutrino magnetic moment from SN1987A is improved by the factor of 3 to 7.Comment: 19 pages, LaTeX, 7 EPS figures, submitted to Journal of Cosmology and Astroparticle Physic

    Flux of Primordial Monopoles

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    We discuss how in supersymmetric models with D and F-flat directions, a primordial monopole flux of order 10^{-16} - 10^{-18} cm^{-2} sec^{-1} sr^{-1} can coexist with the observed baryon asymmetry. A modified Affleck-Dine scenario yields the desired asymmetry if the monopoles are superheavy (~ 10^{13}-10^{18} GeV). For lighter monopoles with masses ~ 10^{9}-10^{12} GeV, the baryon asymmetry can arise via TeV scale leptogenesis.Comment: 17 pages, 4 figures, revtex
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