18,126 research outputs found
Extrinsic versus intrinsic diameter for Riemannian filling-discs and van Kampen diagrams
The diameter of a disc filling a loop in the universal covering of a
Riemannian manifold may be measured extrinsically using the distance function
on the ambient space or intrinsically using the induced length metric on the
disc. Correspondingly, the diameter of a van Kampen diagram filling a word that
represents the identity in a finitely presented group can either be measured
intrinsically its 1-skeleton or extrinsically in the Cayley graph of the group.
We construct the first examples of closed manifolds and finitely presented
groups for which this choice -- intrinsic versus extrinsic -- gives rise to
qualitatively different min-diameter filling functions.Comment: 44 pages, 12 figures, to appear in the Journal of Differential
Geometr
The Potential for Public-Private Partnerships: Philanthropic Leaders Considering Housing as a Platform
Explores foundation leaders' approaches to housing as a platform for layering programs and services to improve quality of life, views on funding partnerships with the federal government, and suggestions for targeted collaborations. Includes case studies
Simulation of gemini-agena docking
Attitude and translation control using visual docking simulator for Gemini/Agena projec
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Suspension Design, Modeling, and Testing of a Thermo-Acoustic-Driven Linear Alternator
The Score-Stove™ generates electricity from a wood-burning cooking stove using a thermo-acoustic engine (TAE) that converts heat to sound through a linear alternator (LA). This paper introduces a prototype hemitoroidal suspension that was refined into a segmented trapezoidal shape that gave a higher cyclic life for the LA and includes a critical evaluation that compares a theoretical analysis with experimental results. The results show an improvement from the 40% efficiency of a standard loudspeaker used in reverse as an LA to 70–80% efficiency with the new suspension and a double Halbach array magnetic topology
Evaluation of the SPAR thermal analyzer on the CYBER-203 computer
The use of the CYBER 203 vector computer for thermal analysis is investigated. Strengths of the CYBER 203 include the ability to perform, in vector mode using a 64 bit word, 50 million floating point operations per second (MFLOPS) for addition and subtraction, 25 MFLOPS for multiplication and 12.5 MFLOPS for division. The speed of scalar operation is comparable to that of a CDC 7600 and is some 2 to 3 times faster than Langley's CYBER 175s. The CYBER 203 has 1,048,576 64-bit words of real memory with an 80 nanosecond (nsec) access time. Memory is bit addressable and provides single error correction, double error detection (SECDED) capability. The virtual memory capability handles data in either 512 or 65,536 word pages. The machine has 256 registers with a 40 nsec access time. The weaknesses of the CYBER 203 include the amount of vector operation overhead and some data storage limitations. In vector operations there is a considerable amount of time before a single result is produced so that vector calculation speed is slower than scalar operation for short vectors
Spectral irradiance of total and spectral energy standards
Spectral irradiance measurements of tungsten and carbon filament lamps for energy standards and accuracy limits used in space simulator
Six Districts Begin the Principal Pipeline Initiative
This first report of an ongoing evaluation of The Wallace Foundation's Principal Pipeline Initiative describes the six participating school districts' plans and activities during the first year of their grants. The evaluation, conducted by Policy Studies Associates and the RAND Corporation, isintended to inform policy makers and practitioners about the process of carrying out new policies and practices for school leadership and about the results of investments in the Principal Pipeline Initiative. This report is based on collection and analysis of qualitative data, including the districts' proposals, work plans, and progress reports and semi-structured interviews in spring 2012 with 91 administrators employed by districts and their partner institutions. Leaders in all districts report wanting to enlarge their pools of strong applicants for principal positions and to identify and cultivate leadership talent as early as possible in educators' careers.Districts are actively working on allrequired pipeline components: (1) with stakeholder participation, they have developed standards and identified competencies for principals, which they plan to use to guide principal training, hiring, evaluation, and support; (2) they are initiating or strengthening partnerships with university training programs; (3) for hiring, they have standard performance tasks and are developing systems to capture data on candidates' experience; (4) they have diagnostic evaluation tools and are working to build the capacity of principals' supervisors and mentors to support principals' skill development. In addition, all are also bolstering district-run training programs for graduates of university training programs who aspire to become principals
Sensitivity of mixing layers to three-dimensional forcing
It is well known that turbulent mixing layers are dominated by large scale, fairly coherent structures, and that these structures are related to the stability characteristics of the flow. These facts have led researchers to attempt controlling such flows by selectively forcing certain unstable modes, which can in addition have the effect of suppressing other modes. Much of the work on controlling the mixing layer has relied on forcing 2-D instabilities. The results of forcing 3-D instabilities are addressed. The objectives of the work are twofold: to understand how a mixing layer responds to 3-D perturbations, and to test the validity of an amplitude expansion in predicting the mixing layer development. The amplitude expansion could be very useful in understanding and predicting the 3-D response of the flow to a variety of initial conditions
NK cells as effectors of acquired immune responses: effector CD4+ T cell-dependent activation of NK cells following vaccination.
We characterized vaccine-induced cellular responses to rabies virus in naive adult volunteers. Contrary to current paradigms, we observed potent and prolonged in vitro NK cell cytokine production and degranulation responses after restimulation of PBMCs with inactivated rabies virus in vaccinated, but not in unvaccinated, individuals. This "recall" NK cell response was absolutely dependent on Ag-specific IL-2 from CD45RO(+) CD4(+) T cells as well as IL-12 and IL-18 from accessory cells. Importantly, NK cells represented over 70% of all IFN-gamma-secreting and degranulating cells in the first 12-18 h after virus rechallenge indicating they may be required for rapid control of infection after vaccination. Activation of NK cells may be a critical function of IL-2-secreting effector memory T cells. Although IL-2-dependent postvaccination NK cell activation has been reported previously, this is the first time the magnitude of this effect and its contribution to the overall vaccine-induced response has been appreciated and the mechanisms of NK activation postvaccination have been elucidated. Our data will allow standard protocols for evaluating vaccine-induced immunity to be adapted to assess NK cell effector responses
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