Neutrino magnetohydrodynamics

A new neutrino magnetohydrodynamics (NMHD) model is formulated, where the effects of the charged weak current on the electron-ion magnetohydrodynamic fluid are taken into account. The model incorporates in a systematic way the role of the Fermi neutrino weak force in magnetized plasmas. A fast neutrino-driven short wavelengths instability associated with the magnetosonic wave is derived. Such an instability should play a central role in strongly magnetized plasma as occurs in supernovae, where dense neutrino beams also exist. In addition, in the case of nonlinear or high frequency waves, the neutrino coupling is shown to be responsible for breaking the frozen-in magnetic field lines condition even in infinite conductivity plasmas. Simplified and ideal NMHD assumptions were adopted and analyzed in detail

Microwave Spectroscopy

Contains reports on four research projects.United States Army Signal Corps (Contract DA36-039-sc-87376)Lincoln Laboratory (Purchase Order DDL B-00368)United States ArmyUnited States NavyUnited States Air Force (Contract AF19(604)-7400

Heat Shock Protein 70 Prevents both Tau Aggregation and the Inhibitory Effects of Preexisting Tau Aggregates on Fast Axonal Transport

Aggregation and accumulation of the microtubule-associated protein tau are associated with cognitive decline and neuronal degeneration in Alzheimer's disease and other tauopathies. Thus, preventing the transition of tau from a soluble state to insoluble aggregates and/or reversing the toxicity of existing aggregates would represent a reasonable therapeutic strategy for treating these neurodegenerative diseases. Here we demonstrate that molecular chaperones of the heat shock protein 70 (Hsp70) family are potent inhibitors of tau aggregation in vitro, preventing the formation of both mature fibrils and oligomeric intermediates. Remarkably, addition of Hsp70 to a mixture of oligomeric and fibrillar tau aggregates prevents the toxic effect of these tau species on fast axonal transport, a critical process for neuronal function. When incubated with preformed tau aggregates, Hsp70 preferentially associated with oligomeric over fibrillar tau, suggesting that prefibrillar oligomeric tau aggregates play a prominent role in tau toxicity. Taken together, our data provide a novel molecular basis for the protective effect of Hsp70 in tauopathies

Study of intrinsic spin and orbital Hall effects in Pt based on a (6s, 6p, 5d) tight-binding model

We study the origin of the intrinsic spin Hall conductivity (SHC) and the d-orbital Hall conductivity (OHC) in Pt based on a multiorbital tight-binding model with spin-orbit interaction. We find that the SHC reaches 1000 \hbar/e\Omega cm when the resistivity \rho is smaller than ~10 \mu\Omega cm, whereas it decreases to 300 \hbar/e\Omega cm when \rho ~ 100 \mu\Omega cm. In addition, the OHC is still larger than the SHC. The origin of huge SHE and OHE in Pt is the large ``effective magnetic flux'' that is induced by the interorbital transition between d_{xy}- and d_{x2-y2}-orbitals with the aid of the strong spin-orbit interaction.Comment: 5 page

Dietary intake of micronutrients and the risk of developing bladder cancer: results from the Belgian case–control study on bladder cancer risk

OBJECTIVE: We aimed to investigate the effect of dietary intake of micronutrients that are metabolized and excreted via the urinary tract on bladder cancer risk. METHODS: A semi-quantitative 322 item food frequency questionnaire (FFQ) was used to collect dietary data from 200 bladder cancer cases and 386 control subjects participating in the Belgian case-control study on bladder cancer risk. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using unconditional logistic regression adjusting for age, sex, smoking characteristics, occupational exposures, and energy intake. RESULTS: We observed a positive association between calcium intake and bladder cancer (OR: 1.77; 95% CI: 1.00-3.15; p-trend = 0.049) and increased odds, although not statistically significant, for highest tertile of phosphorus intake (OR: 1.82; 95% CI: 0.95-3.49; p-trend = 0.06). We identified possible modification of the effects of both calcium and phosphorus by level of magnesium intake. Increased odds of bladder cancer were also observed for participants with highest intake of phosphorus and lowest intake of vitamin D (OR: 4.25; 95% CI: 1.44-12.55) and among older participants with the highest intakes of calcium (OR: 1.90; 95% CI: 1.08-3.36) and phosphorus (OR: 2.02; 95% CI: 1.05-3.92). CONCLUSION: The positive associations we observed between bladder cancer and intake of calcium and phosphorus require confirmation by other studies. The balances between inter-related micronutrients also warrant further examination

Sex-based differences in functional brain activity during working memory in survivors of pediatric acute lymphoblastic leukemia

BACKGROUND: Long-term survivors of pediatric acute lymphoblastic leukemia are at elevated risk for neurocognitive deficits and corresponding brain dysfunction. This study examined sex-based differences in functional neuroimaging outcomes in acute lymphoblastic leukemia survivors treated with chemotherapy alone. METHODS: Functional magnetic resonance imaging (fMRI) and neurocognitive testing were obtained in 123 survivors (46% male; median [min-max] age = 14.2 years [8.3-26.5 years]; time since diagnosis = 7.7 years [5.1-12.5 years]) treated on the St. Jude Total XV treatment protocol. Participants performed the n-back working memory task in a 3 T scanner. Functional neuroimaging data were processed (realigned, slice time corrected, normalized, smoothed) and analyzed using statistical parametric mapping with contrasts for 1-back and 2-back conditions, which reflect varying degrees of working memory and task load. Group-level fMRI contrasts were stratified by sex and adjusted for age and methotrexate exposure. Statistical tests were 2-sided (P \u3c .05 statistical significance threshold). RESULTS: Relative to males, female survivors exhibited less activation (ie, reduced blood oxygen dependent-level signals) in the right parietal operculum, supramarginal gyrus and inferior occipital gyrus, and bilateral superior frontal medial gyrus during increased working memory load (family-wise error-corrected P = .004 to .008, adjusting for age and methotrexate dose). Female survivors were slower to correctly respond to the 2-back condition than males (P \u3c .05), though there were no differences in overall accuracy. Performance accuracy was negatively correlated with fMRI activity in female survivors (Pearson\u27s r = -0.39 to -0.29, P = .001 to .02), but not in males. CONCLUSIONS: These results suggest the working memory network is more impaired in female survivors than male survivors, which may contribute to ongoing functional deficits

Interpolating self-energy of the infinite-dimensional Hubbard model: Modifying the iterative perturbation theory

We develop an analytical expression for the self-energy of the infinite-dimensional Hubbard model that is correct in a number of different limits. The approach represents a generalization of the iterative perturbation theory to arbitrary fillings. In the weak-coupling regime perturbation theory to second order in the interaction U is recovered. The theory is exact in the atomic limit. The high-energy behavior of the self-energy up to order (1/E)**2 and thereby the first four moments of the spectral density are reproduced correctly. Referring to a standard strong-coupling moment method, we analyze the limit of strong U. Different modifications of the approach are discussed and tested by comparing with the results of an exact diagonalization study.Comment: LaTeX, 14 pages, 5 ps figures included, title changed, references updated, minor change

A Study of the Antiferromagnetic Phase in the Hubbard Model by means of the Composite Operator Method

We have investigated the antiferromagnetic phase of the 2D, the 3D and the extended Hubbard models on a bipartite cubic lattice by means of the Composite Operator Method within a two-pole approximation. This approach yields a fully self-consistent treatment of the antiferromagnetic state that respects the symmetry properties of both the model and the algebra. The complete phase diagram, as regards the antiferromagnetic and the paramagnetic phases, has been drawn. We firstly reported, within a pole approximation, three kinds of transitions at half-filling: Mott-Hubbard, Mott-Heisenberg and Heisenberg. We have also found a metal-insulator transition, driven by doping, within the antiferromagnetic phase. This latter is restricted to a very small region near half filling and has, in contrast to what has been found by similar approaches, a finite critical Coulomb interaction as lower bound at half filling. Finally, it is worth noting that our antiferromagnetic gap has two independent components: one due to the antiferromagnetic correlations and another coming from the Mott-Hubbard mechanism.Comment: 20 pages, 37 figures, RevTeX, submitted to Phys. Rev.