Evolution of close binary systems: Observational aspects

Detached close binary systems define the main sequence band satisfactorily, but very little is known about the masses of giants and supergiants. High dispersion international ultraviolet explorer satellite observations promise an improvement, since blue companions are now frequently found to late type supergiants. Mu Sagittaril and in particular Xi Aurigae are discussed in more detail. The barium star abundance anomaly appears to be due to mass transfer in interacting systems. The symbiotic stars are another type of binary systems containing late type giants; several possible models for the hotter star and for the type of interaction are discussed. The W Serpentis stars appear to be Algols in the rapid phase of mass transfer, but a possible link relating them to the symbiotics is also indicated. Evidence of hot circumstellar plasmas has now been found in several ordinary Algols; there may exist a smooth transition between very quiescent Algols and the W Serpentis stars. Beta Lyrae is discussed in the light of new spectrophotometric results

The Roche problem: some analytics

Some exact analytical formulas are derived for the potential and mass ratio as a function of Lagrangian points position, in the classical Roche model of the close binary stars.Comment: aastex, 4 pp. ApJ accepte

Analysis of the symbiotic star AG Pegasi

High and low dispersion IUE data are analyzed in conjunction with coincident ground based spectrophotometric scans and supplementary infrared photometry of the symbiotic object AG Pegasi. The IUE observations yield an improved value of E(B-V) = 0.12. The two stellar components are easily recognized in the spectra. The cool component may be an M1.7 III star and the hot component appears to have T (sub eff) of approximately 30000 K. The emission lines observed in the ultraviolet indicate two or three distince emitting regions. Nebular component ultraviolet intercombination lines suggest an electron density of several times 10 billion/cu cm

Synthetic NLTE accretion disc spectra for the dwarf nova SS Cyg during an outburst cycle

Dwarf nova outbursts result from enhanced mass transport through the accretion disc of a cataclysmic variable system. We assess the question of whether these outbursts are caused by an enhanced mass transfer from the late-type main sequence star onto the white dwarf (so-called mass transfer instability model, MTI) or by a thermal instability in the accretion disc (disc instability model, DIM). We compute non-LTE models and spectra of accretion discs in quiescence and outburst and construct spectral time sequences for discs over a complete outburst cycle. We then compare our spectra to published optical spectroscopy of the dwarf nova SS Cygni. In particular, we investigate the hydrogen and helium line profiles that are turning from emission into absorption during the rise to outburst. The evolution of the hydrogen and helium line profiles during the rise to outburst and decline clearly favour the disc-instability model. Our spectral model sequences allow us to distinguish inside-out and outside-in moving heating waves in the disc of SS Cygni, which can be related to symmetric and asymmetric outburst light curves, respectively.Comment: 8 pages, 8 figures; accepted to A&

The "K-Correction" for Irradiated Emission Lines in LMXBs: Evidence for a Massive Neutron Star in X1822-371 (V691 CrA)

We study the K-correction for the case of emission lines formed in the X-ray illuminated atmosphere of a Roche lobe filling star. We compute the K-correction as function of the mass ratio 'q' and the disc flaring angle 'alpha' using a compact binary code where the companion's Roche lobe is divided into 10^5 resolution elements. We also study the effect of the inclination angle in the results. We apply our model to the case of the neutron star low-mass X-ray binary X1822-371 (V691 CrA), where a K-emission velocity K_em=300 +-8 km/s has been measured by Casares et al. (2003). Our numerical results, combined with previous determination of system parameters, yields 1.61Msun < M_NS < 2.32Msun and 0.44Msun < M_2 < 0.56Msun for the two binary components(i. e. 0.24 < q < 0.27), which provide a compelling evidence for a massive neutron star in this system. We also discuss the implications of these masses into the evolutionary history of the binary.Comment: 6 pages, 5 figures. Accepted for publication in Ap

Equipotential Surfaces and Lagrangian points in Non-synchronous, Eccentric Binary and Planetary Systems

We investigate the existence and properties of equipotential surfaces and Lagrangian points in non-synchronous, eccentric binary star and planetary systems under the assumption of quasi-static equilibrium. We adopt a binary potential that accounts for non-synchronous rotation and eccentric orbits, and calculate the positions of the Lagrangian points as functions of the mass ratio, the degree of asynchronism, the orbital eccentricity, and the position of the stars or planets in their relative orbit. We find that the geometry of the equipotential surfaces may facilitate non-conservative mass transfer in non-synchronous, eccentric binary star and planetary systems, especially if the component stars or planets are rotating super-synchronously at the periastron of their relative orbit. We also calculate the volume-equivalent radius of the Roche lobe as a function of the four parameters mentioned above. Contrary to common practice, we find that replacing the radius of a circular orbit in the fitting formula of Eggleton (1983) with the instantaneous distance between the components of eccentric binary or planetary systems does not always lead to a good approximation to the volume-equivalent radius of the Roche-lobe. We therefore provide generalized analytic fitting formulae for the volume-equivalent Roche lobe radius appropriate for non-synchronous, eccentric binary star and planetary systems. These formulae are accurate to better than 1% throughout the relevant 2-dimensional parameter space that covers a dynamic range of 16 and 6 orders of magnitude in the two dimensions.Comment: 12 pages, 10 figures, 2 Tables, Accepted by the Astrophysical Journa

Identification and characterisation of G-quadruplex DNA-forming sequences in the Pseudomonas aeruginosa genome

A number of Gram-negative bacteria such as Pseudomonas aeruginosa are becoming resistant to front-line antibiotics. Consequently, there is a pressing need to find alternative bio-molecular targets for the development of new drugs. Since non-canonical DNA structures such as guanine-quadruplexes (G4s) have been implicated in regulating transcription, we were interested in determining whether there are putative quadruplex-forming sequences (PQS) in the genome of Pseudomonas aeruginosa. Using bioinformatic tools, we screened 36 genes potentially relevant to drug resistance for the presence of PQS and 10 of these were selected for biophysical characterisation (i.e. circular dichroism and thermal difference UV/Vis spectroscopy). These studies showed that three of these G-rich sequences (linked to murE, ftsB and mexC genes) form stable guanine-quadruplexes which were studied by NMR spectroscopy; detailed analysis of one of the sequences (mexC) confirmed that it adopts a two-quartet antiparallel quadruplex structure in the presence of K+ ions. We also show by FRET melting assays that small molecules can stabilise these three new G4 DNA structures under physiological conditions. These initial results could be of future interest in the development of new antibiotics with alternative bio-molecular targets which in turn would help tackle antimicrobial resistance

Modifiable Risk Factors for Common Ragweed (Ambrosia artemisiifolia) Allergy and Disease in Children: A Case-Control Study

Ragweed allergy is a major public health concern. Within Europe, ragweed is an introduced species and research has indicated that the amounts of ragweed pollen are likely to increase over Europe due to climate change, with corresponding increases in ragweed allergy. To address this threat, improving our understanding of predisposing factors for allergic sensitisation to ragweed and disease is necessary, specifically focusing upon factors that are potentially modifiable (i.e., environmental). In this study, a total of 4013 children aged 2–13 years were recruited across Croatia to undergo skin prick tests to determine sensitisation to ragweed and other aeroallergens. A parental questionnaire collected home environment, lifestyle, family and personal medical history, and socioeconomic information. Environmental variables were obtained using Geographical Information Systems and data from nearby pollen, weather, and air pollution stations. Logistic regression was performed (clustered on school) focusing on risk factors for allergic sensitisation and disease. Ragweed sensitisation was strongly associated with ragweed pollen at levels over 5000 grains m–3 year−1 and, above these levels, the risk of sensitisation was 12–16 times greater than in low pollen areas with about 400 grains m–3 year−1. Genetic factors were strongly associated with sensitisation but nearly all potentially modifiable factors were insignificant. This included measures of local land use and proximity to potential sources of ragweed pollen. Rural residence was protective (odds ratio (OR) 0.73, 95% confidence interval (CI) 0.55–0.98), but the factors underlying this association were unclear. Being sensitised to ragweed doubled (OR 2.17, 95% CI 1.59–2.96) the risk of rhinoconjunctivitis. No other potentially modifiable risk factors were associated with rhinoconjunctivitis. Ragweed sensitisation was strongly associated with ragweed pollen, and sensitisation was significantly associated with rhinoconjunctivitis. Apart from ragweed pollen levels, few other potentially modifiable factors were significantly associated with ragweed sensitisation. Hence, strategies to lower the risk of sensitisation should focus upon ragweed control

Ragweed pollen and allergic symptoms in children: Results from a three-year longitudinal study

Common ragweed is a highly allergenic invasive species in Europe, expected to become widespread under climate change. Allergy to ragweed manifests as eye, nasal and lung symptoms, and children may retain these throughout life. The dose-response relationship between symptoms and pollen concentrations is unclear. We undertook a longitudinal study, assessing the association between ragweed pollen concentration and allergic eye, nasal and lung symptoms in children living under a range of ragweed pollen concentrations in Croatia. Over three years, 85 children completed daily diaries, detailing allergic symptoms alongside daily location, activities and medication, resulting in 10,130 individual daily entries. The daily ragweed pollen concentration for the children's locations was obtained, alongside daily weather and air pollution. Parents completed a home/lifestyle/medical questionnaire. Generalised Additive Mixed Models established the relationship between pollen concentrations and symptoms, alongside other covariates. Eye symptoms were associated with mean daily pollen concentration over four days (day of symptoms plus 3 previous days); 61 grains/m3/day (95%CI: 45, 100) was the threshold at which 50% of children reported symptoms. Nasal symptoms were associated with mean daily pollen concentration over 12 days (day of symptoms plus 11 previous days); the threshold for 50% of children reporting symptoms was 40 grains/m3/day (95%CI: 24, 87). Lung symptoms showed a relationship with mean daily pollen concentration over 19 days (day of symptoms plus 18 previous days), with a threshold of 71 grains/m3/day (95%CI: 59, 88). Taking medication on the day of symptoms showed higher odds, suggesting responsive behaviour. Taking medication on the day prior to symptoms showed lower odds of reporting, indicating preventative behaviour. Different symptoms in children demonstrate varying dose-response relationships with ragweed pollen concentrations. Each symptom type responded to pollen exposure over different time periods. Using medication prior to symptoms can reduce symptom presence. These findings can be used to better manage paediatric ragweed allergy symptoms