278 research outputs found

    Quark-antiquark composite systems: the Bethe-Salpeter equation in the spectral-integration technique

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    The Bethe-Salpeter equations for the light-quark composite systems, q q-bar, are written in terms of spectral integrals. For the q q-bar -mesons characterized by the mass M, spin J and radial quantum number n, the equations are presented for the following (n,M^2)-trajectories: pi_J, eta_J, a_J, f_J, rho_J, omega_J, h_J and b_J.Comment: 42 pages, 5 figures, typos correcte

    The Political Economy of Myanmar's Transition

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    This is an Author's Original Manuscript of an article whose final and definitive form, the Version of Record, has been published in the JOURNAL OF CONTEMPORARY ASIA, 07 Feb 2013, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/00472336.2013.764143.Since holding elections in 2010, Myanmar has transitioned from a direct military dictatorship to a formally democratic system and has embarked on a period of rapid economic reform. After two decades of military rule, the pace of change has startled almost everyone and led to a great deal of cautious optimism. To make sense of the transition and assess the case for optimism, this article explores the political economy of Myanmar's dual transition from state socialism to capitalism and from dictatorship to democracy. It analyses changes within Myanmar society from a critical political economy perspective in order to both situate these developments within broader regional trends and to evaluate the country's current trajectory. In particular, the emergence of state-mediated capitalism and politico-business complexes in Myanmar's borderlands are emphasised. These dynamics, which have empowered a narrow oligarchy, are less likely to be undone by the reform process than to fundamentally shape the contours of reform. Consequently, Myanmar's future may not be unlike those of other Southeast Asian states that have experienced similar developmental trajectories

    An ultrasensitive reverse transcription polymerase chain reaction assay to detect asymptomatic low-density Plasmodium falciparum and Plasmodium vivax infections in small volume blood samples.

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    BackgroundHighly sensitive, scalable diagnostic methods are needed to guide malaria elimination interventions. While traditional microscopy and rapid diagnostic tests (RDTs) are suitable for the diagnosis of symptomatic malaria infection, more sensitive tests are needed to screen for low-density, asymptomatic infections that are targeted by interventions aiming to eliminate the entire reservoir of malaria infection in humans.MethodsA reverse transcription polymerase chain reaction (RT- PCR) was developed for multiplexed detection of the 18S ribosomal RNA gene and ribosomal RNA of Plasmodium falciparum and Plasmodium vivax. Simulated field samples stored for 14 days with sample preservation buffer were used to assess the analytical sensitivity and specificity. Additionally, 1750 field samples from Southeastern Myanmar were tested both by RDT and ultrasensitive RT-PCR.ResultsLimits of detection (LoD) were determined under simulated field conditions. When 0.3 mL blood samples were stored for 14 days at 28 °C and 80% humidity, the LoD was less than 16 parasites/mL for P. falciparum and 19.7 copies/µL for P. vivax (using a plasmid surrogate), about 10,000-fold lower than RDTs. Of the 1739 samples successfully evaluated by both ultrasensitive RT-PCR and RDT, only two were RDT positive while 24 were positive for P. falciparum, 108 were positive for P. vivax, and 127 were positive for either P. vivax and/or P. falciparum using ultrasensitive RT-PCR.ConclusionsThis ultrasensitive RT-PCR method is a robust, field-tested screening method that is vastly more sensitive than RDTs. Further optimization may result in a truly scalable tool suitable for widespread surveillance of low-level asymptomatic P. falciparum and P. vivax parasitaemia

    Calibrated Sub-Bundles in Non-Compact Manifolds of Special Holonomy

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    This paper is a continuation of math.DG/0408005. We first construct special Lagrangian submanifolds of the Ricci-flat Stenzel metric (of holonomy SU(n)) on the cotangent bundle of S^n by looking at the conormal bundle of appropriate submanifolds of S^n. We find that the condition for the conormal bundle to be special Lagrangian is the same as that discovered by Harvey-Lawson for submanifolds in R^n in their pioneering paper. We also construct calibrated submanifolds in complete metrics with special holonomy G_2 and Spin(7) discovered by Bryant and Salamon on the total spaces of appropriate bundles over self-dual Einstein four manifolds. The submanifolds are constructed as certain subbundles over immersed surfaces. We show that this construction requires the surface to be minimal in the associative and Cayley cases, and to be (properly oriented) real isotropic in the coassociative case. We also make some remarks about using these constructions as a possible local model for the intersection of compact calibrated submanifolds in a compact manifold with special holonomy.Comment: 20 pages; for Revised Version: Minor cosmetic changes, some paragraphs rewritten for improved clarit

    Bound q\bar q Systems in the Framework of the Different Versions of the 3-Dimensional Reductions of the Bethe-Salpeter Equation

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    Bound q\bar q systems are studied in the framework of different 3-dimensional relativistic equations derived from the Bethe-Salpeter equation with the instantaneous kernel in the momentum space. Except the Salpeter equation, all these equations have a correct one-body limit when one of the constituent quark masses tends to infinity. The spin structure of the confining qq interaction potential is taken in the form xγ10γ20+(1x)I1I2x\gamma_{1}^{0}\gamma_{2}^{0}+(1-x)I_{1}I_{2}, with 0x10\leq x \leq 1. At first stage, the one-gluon-exchange potential is neglected and the confining potential is taken in the oscillator form. For the systems (u\bar s), (c\bar u), (c\bar s) and (u\bar u), (s\bar s) a comparative qualitative analysis of these equations is carried out for different values of the mixing parameter x and the confining potential strength parameter. We investigate: 1)the existence/nonexistence of stable solutions of these equations; 2) the parameter dependence of the general structure of the meson mass spectum and leptonic decay constants of pseudoscalar and vector mesons. It is demonstrated that none of the 3-dimensional equations considered in the present paper does simultaneously describe even general qualitative features of the whole mass spectrum of q\bar q systems. At the same time, these versions give an acceptable description of the meson leptonic decay characteristics.Comment: 22 pages, 5 postscript figures, LaTeX-file (revtex.sty

    Charmed quark component of the photon wave function

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    We determine the c-anti-c component of the photon wave function on the basis of (i) the data on the transitions e+ e- -> J/psi(3096), psi(3686), psi(4040), psi(4415), (ii) partial widths of the two-photon decays eta_{c0}(2979), chi_{c0}(3415), chi_{c2}(3556) -> gamma-gamma, and (iii) wave functions of the charmonium states obtained by solving the Bethe-Salpeter equation for the c-anti-c system. Using the obtained c-anti-c component of the photon wave function we calculate the gamma-gamma decay partial widths for radial excitation 2S state, eta_{c0}(3594) -> gamma-gamma, and 2P states chi_{c0}(3849), chi_{c2}(3950) -> gamma-gamma.Comment: 20 pages, 8 figure

    Quark--antiquark states and their radiative transitions in terms of the spectral integral equation. {\Huge II.} Charmonia

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    In the precedent paper of the authors (hep-ph/0510410), the bbˉb\bar b states were treated in the framework of the spectral integral equation, together with simultaneous calculations of radiative decays of the considered bottomonia. In the present paper, such a study is carried out for the charmonium (ccˉ)(c\bar c) states. We reconstruct the interaction in the ccˉc\bar c-sector on the basis of data for the charmonium levels with JPC=0+J^{PC}=0^{-+}, 11^{--}, 0++0^{++}, 1++1^{++}, 2++2^{++}, 1+1^{+-} and radiative transitions ψ(2S)γχc0(1P)\psi(2S)\to\gamma\chi_{c0}(1P), γχc1(1P)\gamma\chi_{c1}(1P), γχc2(1P)\gamma\chi_{c2}(1P), γηc(1S)\gamma\eta_{c}(1S) and χc0(1P)\chi_{c0}(1P), χc1(1P)\chi_{c1}(1P), χc2(1P)γJ/ψ\chi_{c2}(1P)\to\gamma J/\psi. The ccˉc\bar c levels and their wave functions are calculated for the radial excitations with n6n\le 6. Also, we determine the ccˉc\bar c component of the photon wave function using the e+ee^+e^- annihilation data: e+eJ/ψ(3097)e^+e^- \to J/\psi(3097), ψ(3686)\psi(3686), ψ(3770)\psi(3770), ψ(4040)\psi(4040), ψ(4160) \psi(4160), ψ(4415)\psi(4415) and perform the calculations of the partial widths of the two-photon decays for the n=1n=1 states: ηc0(1S)\eta_{c0}(1S), χc0(1P)\chi_{c0}(1P), χc2(1P)γγ\chi_{c2}(1P)\to\gamma\gamma, and n=2n=2 states: ηc0(2S)γγ\eta_{c0}(2S)\to\gamma\gamma, χc0(2P)\chi_{c0}(2P), χc2(2P)γγ\chi_{c2}(2P)\to \gamma\gamma. We discuss the status of the recently observed ccˉc\bar c states X(3872) and Y(3941): according to our results, the X(3872) can be either χc1(2P)\chi_{c1}(2P) or ηc2(1D)\eta_{c2}(1D), while Y(3941) is χc2(2P)\chi_{c2}(2P).Comment: 24 pages, 9 figure

    Quark-diquark Systematics of Baryons: Spectral Integral Equations for Systems Composed by Light Quarks

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    For baryons composed by the light quarks (q=u,dq=u,d) we write spectral integral equation using the notion of two diquarks: (i) axial--vector state, D11D^{1}_{1}, with the spin SD=1S_D=1 and isospin ID=1I_D=1 and (ii) scalar one, D00D^{0}_{0}, with the spin SD=0S_D=0 and isospin ID=0I_D=0. We present spectral integral equations for the qD00qD^{0}_{0} and qD11qD^{1}_{1} states taking into account quark--diquark confinement interaction.Comment: 13 pages, 2 figure

    Rhinobatos annandalei, Bengal Guitarfish

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    The Bengal Guitarfish (Rhinobatos annandalei) is a small (to 95 cm total length) guitarfish that occurs in the northern Indian Ocean from the United Arab Emirates (UAE) to Bangladesh, including Sri Lanka. The western boundary of this species distribution is uncertain due to confusion with the Spotted Guitarfish (R. punctifer). It is demersal on the inner continental shelf at depths of 5–73 m. The species is mainly a bycatch of a range of industrial and artisanal gears including demersal trawls, longlines, and gillnets. The meat is consumed locally and traded internationally, and the skins are exported from Bangladesh to Myanmar to be made into accessories (e.g. handbags). There is a high level of fisheries resource use and increasing fishing pressure across the range of this species. Severe population reduction is inferred from actual levels of exploitation, as well as several historical accounts and contemporary datasets from the UAE, Iran, Pakistan, and India. Landings data of guitarfishes and rays from the UAE, Iran, Pakistan, India, and Bangladesh indicate landings declines of 69–93% consistent with population reductions of 80% over the past three generation lengths (27 years). These levels of declines are not species-specific but are informative for understanding the broader levels of guitarfish decline in the region. It is suspected that the Bengal Guitarfish has undergone a population reduction of >80% over the past three generation lengths (27 years) due to actual levels of exploitation, and it is assessed as Critically Endangered A2d

    Population Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis.

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    BACKGROUND: Artemisinin-based combination therapies (ACTs) are the mainstay of the current treatment of uncomplicated Plasmodium falciparum malaria, but ACT resistance is spreading across Southeast Asia. Dihydroartemisinin-piperaquine is one of the five ACTs currently recommended by the World Health Organization. Previous studies suggest that young children (<5 y) with malaria are under-dosed. This study utilised a population-based pharmacokinetic approach to optimise the antimalarial treatment regimen for piperaquine. METHODS AND FINDINGS: Published pharmacokinetic studies on piperaquine were identified through a systematic literature review of articles published between 1 January 1960 and 15 February 2013. Individual plasma piperaquine concentration-time data from 11 clinical studies (8,776 samples from 728 individuals) in adults and children with uncomplicated malaria and healthy volunteers were collated and standardised by the WorldWide Antimalarial Resistance Network. Data were pooled and analysed using nonlinear mixed-effects modelling. Piperaquine pharmacokinetics were described successfully by a three-compartment disposition model with flexible absorption. Body weight influenced clearance and volume parameters significantly, resulting in lower piperaquine exposures in small children (<25 kg) compared to larger children and adults (≥25 kg) after administration of the manufacturers' currently recommended dose regimens. Simulated median (interquartile range) day 7 plasma concentration was 29.4 (19.3-44.3) ng/ml in small children compared to 38.1 (25.8-56.3) ng/ml in larger children and adults, with the recommended dose regimen. The final model identified a mean (95% confidence interval) increase of 23.7% (15.8%-32.5%) in piperaquine bioavailability between each piperaquine dose occasion. The model also described an enzyme maturation function in very young children, resulting in 50% maturation at 0.575 (0.413-0.711) y of age. An evidence-based optimised dose regimen was constructed that would provide piperaquine exposures across all ages comparable to the exposure currently seen in a typical adult with standard treatment, without exceeding the concentration range observed with the manufacturers' recommended regimen. Limited data were available in infants and pregnant women with malaria as well as in healthy individuals. CONCLUSIONS: The derived population pharmacokinetic model was used to develop a revised dose regimen of dihydroartemisinin-piperaquine that is expected to provide equivalent piperaquine exposures safely in all patients, including in small children with malaria. Use of this dose regimen is expected to prolong the useful therapeutic life of dihydroartemisinin-piperaquine by increasing cure rates and thereby slowing resistance development. This work was part of the evidence that informed the World Health Organization technical guidelines development group in the development of the recently published treatment guidelines (2015)
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